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Biomedical subjects

G Guiraudon

Publications and source records attributed to G Guiraudon.

At least 55 records · Page 3Linked to original sources

[Prophylactic intra-aortic balloon pumping in the surgery of the left main coronary artery].

92 significant stenoses of the left main stem artery (LCA) underwent revascularisation procedures by aorto-coronary venous bypass grafting. Three groups of patients were identified. Group I comprised 11 stenoses of the LCA associated with lesions of at least three other coronary vessels and a subtotal stenosis of the LCA. These patients underwent systematic prophylactic intra-aortic balloon counter-pulsation (IACP) when they were taken off cardiopulmonary bypass. Group II comprised 47 patients with stenosis of the LCA and at least three coronary vessels. IACP was required in 6 cases in whom difficulty was experienced at the end of cardiopulmonary bypass, or after haemodynamic decompensation. Group II comprised 33 stenoses of the LCA which were isolated or associated with lesions of 1 or 2 vessels. The operative risk increased with the severity of the coronary lesions associated with LCA stenosis. 6 p. 100 deaths occurred in Group III, compared to 21 p. 100 in Group II (p = 0.06). the use of IACP before the onset of possible haemodynamic decompensation improved the operative prognosis of stenosis of the LCA associated with lesions of at least three coronary vessels. Mortality in Group I was 0 p. 100, compared to 21 p. 100 in Group II (p = 0.09). Prophylactic IABP also seemed to decrease the number of perioperative infarctions: Group I, 16 p. 100, Group II, 36 p. 100, but p > 0.01. analysis of global mortality (12 cases) showed that 50 p. 100 patients (6 cases) had ejection fractions of less than 0.50. In agreement with other authors, we found that systematic IABP improved the operative prognosis in stenosis of the LCA. However, we do not advocate its use in every case. A selection of high risk patients seems a reasonable objective. The severity of the coronary lesions associated with LCA stenosis is statistically a good criteria of selection. The incidence of left ventricular hypokinesis with an ejection fraction less than 0.50 in the deceased patients, is a factor in favouring the use of prophylactic IACP in left ventricular dysfunction.

Arterial Occlusive Diseases↗

[Results of open heart mitral commissurotomy in 85 patients].

Open heart mitral commissurotomy was performed in 85 patients between January 1973 and January 1976. This series comprised 38 patients with pure mitral stenosis and 47 patients with associated mitral and aortic or tricuspid lesions. Mitral commissurotomy, always complete, was associated with correction of mitral incompetence, either preexisting or peroperative, in 19 cases; in 44 cases with correction of an aortic lesion and in 10 cases with correction of a tricuspid lesion. The surgical mortality was 2.3 p. 100 (2 deaths); one post-operative myocardial infarction and one spontaneously regressive post-operative jaudice was observed. No cases of post-operative systemic embolism was observed. A short apical systolic murmur was detected in 12 cases. The results of this series together with those already published suggest that the indications of this operation should be widened and that it should be employed whenever the best immediate anatomical result and long-term prognosis are desired.

Adolescent↗

[Coronary endarterectomy associated with coronary artery bypass in severe coronary artery disease. 50 cases].

The surgical indications of coronary endarterectomy were defined from a study of 50 cases in which endarterectomy was associated with aorto-coronary bypass surgery. This total represented 6 p. 100 of all the aorto-coronary bypass operations performed in the same period. Coronary endarterectomy was performed "on principal" for the right coronary artery, and "of necessity" for the left anterior descending artery. The special techniques of endarterectomy on the left anterior descending artery are described. Endarterectomy does not increase the operative risk and enables revascularisation of vessels unsuitable for bypass surgery. 85 p. 100 patients are asymptomatic with an average follow up period of 2 years after endarterectomy and aorto-coronary bypass graft of the right coronary artery.

Adult↗

The surgical management of ventricular tachycardia.

A better understanding of the mechanisms of chronic ventricular arrhythmias has led to the development of new surgical techniques for their management with promising results. Simple ventriculotomy is particularly useful in idiopathic ventricular tachycardia (19 cases). Ventricular tachycardia complicating myocardial infarction may be a special indication for an encircling subendocardial ventriculotomy (12 cases).

Chronic Disease↗

Encircling endocardial ventriculotomy: a new surgical treatment for life-threatening ventricular tachycardias resistant to medical treatment following myocardial infarction.

Ventricular tachycardias occurring after myocardial infarction (MI) and resistant to medical treatment were successfully treated in 5 patients by encircling endocardial ventriculotomy. All patients had a history of MI. The delay between MI and ventricular tachycardias ranged from 1 month to 8 years. A reentrant mechanism was demonstrated by laboratory studies. Under cardiopulmonary bypass, the left ventricle was entered through the thin fribrous scar. Encircling endocardial ventriculotomy was carried out from the inside of the ventricle, through the whole thickness of the normal myocardium, and along the border of the endocardial fibrosis, which delineated the area of diseased myocardium. The ventriculotomy was placed in the free wall or in the septum or in both of these locations. It was repaired and the left ventricle was closed. Drug therapy was discontinued after operation. No ventricular tachycardias recurred during a follow-up period of 6 to 24 months. The effectiveness of encircling endocardial ventriculotomy is explained by the exclusion of the entire diseased area, especially the border zone and the septum. This technique is useful in any location of MI.

Cardiopulmonary Bypass↗

[Recurrent ventricular tachycardia and parchment right ventricle in the adult. Anatomical and clinical report of 2 cases].

Two patients, aged 52 and 55 years, were admitted to hospital for attacks of recurrent ventricular tachycardia for which preventive treatment was difficult. The crises were of one type, with left-sided delay. The findings on clinical examination, electrocardiography, haemodynamic and arteriographic investigation and at post-mortem were those of the parchment right ventricle syndrome of the adult. Electrophysiological investigation in the 2 cases indicated that a re-entry mechanism underlay the attacks of tachycardia. Late activation of the pulmonary infundibulum was responsible for a post-excitation potential on the surface and intra-cavitary leads. Mapping carried out during ventricular tachycardia in one case demonstrated the pathway for re-entry at the level of the pulmonary infundibulum.

Electrophysiology↗

[Mitral valve insufficiency due to ballooning. A surgical series of 70 cases].

The authors report 70 cases of mitral regurgitation due to ballooning. For the surgeon this is the most frequent cause of degenerative mitral regurgitation in patients around 60-years-old. The aetiology still remains unknown. There are two opposing theories--the congenital and the acquired. The appearances at operation are characteristic--a localised or diffuse ballooning of one or both cusps with elongation of the chordae attached to the ballooned portion. Two histological features are noted--myxomatous degeneration of the cusp and the absence of any inflammatory process. Ballooning may be asymptomatic and bening for a long time before evolving progressively or suddenly into important mitral regurgitation. The pre-operative diagnosis is aided by left ventricular angiography and echocardiography. Surgical treatment, guided by the findings at operation, usually involves mitral valve replacement or, less frequently, mitral valve repair.

Adult↗

[Aneurysm of Valsalva's sinus, apropos of 7 surgical cases[].

The authors describe 7 cases of rupture of the Valsalva sinus. Until rupture the aneurysm is silent. Aortic insufficiency and left to right shunt are major components of this syndrome. Surgical treatment under extra-corporal circulation needs aortotomy and an approach of the ruptured extremity to close the defect and maintaining the integrity of the valvular structures.

Adolescent↗

[Pseudoaneuysms of the heart after myocardial infarct. Apropos of 5 operated cases].

The authors base themselves on 5 personal cases and a review of the literature to summarise the clinical and paraclinical features of false aneurysms of the heart. The clinical features differ from those of true aneurysms only slightly. It is only arteriography, which shows up the collar and the slow evacuation of the cavity, which makes the real distinction and argues in favour of operation. The results of surgical treatment have been satisfactory, especially considering the natural outcome, which is always death from rupture.

Aged↗

[Angina pectoris and muscular bridges on the anterior interventricular artery. Apropos of 3 operated cases].

A relationship between ischaemia of the myocardium and a muscular bridge over the anterios descending artery has now been demonstrated. The authors report three cases in which the severity of the clinical features was sufficient to justify surgical division of the muscular bridge without touching the underlying artery. Progress remained satisfactory after a follow-up period of 1.5 to 3 years. The opportunity is taken to discuss the role of the muscle bridge in causing pathology in the coronary arterial system.

Adult↗