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Biomedical subjects

G Guillard

Publications and source records attributed to G Guillard.

At least 19 recordsLinked to original sources
PubMed1994

[Reoperation by thoracic approach after surgery for gastroesophageal reflux].

Eleven patients underwent left transthoracic reoperation for recurrence of hiatus hernia after previous surgical treatment. A left thoracic approach was chosen because of three cases of major obesity, three patients with multiple previous laparotomies, three recurrences of para-esophageal hernia, three associated dyskinetic disorders of lower esophagus. Ten patients underwent a Belsey Mark IV procedure with three myotomies of lower esophagus and one pyloroplasty. One patient underwent a Collis-Belsey procedure. Operative mortality was zero. Every patient had been followed up with a mean of 31 months. Ten patients have a good result. One patient had a massive recurrence of gastroesophageal reflux after Belsey Mark IV which led to a duodenal diversion 18 months later. Although the abdominal approach allows easier dissection of lower esophagus and complementary procedures to the lower esophagus. Results are as good as those of the abdominal approach.

Adult↗
PubMed1992

[Kidney procurement after rapid cooling in situ through a double intra-aortic balloon].

We report a series of 12 kidneys harvested from 8 brain-dead patients with unstable haemodynamic condition after in situ renal cooling using the double balloon technique. Material and technique are described. The outcome of the renal grafts is known at 3 and 12 months: 92 percent of the renal grafts were functioning at 3 months and 87 percent at 12 months. The mean serum creatinine level of the recipients with functioning graft was 135 mumol/l at 3 months and 113 mumol/l at 12 months. These results suggest that the in situ renal cooling technique makes it possible to obtain kidneys under unstable haemodynamic conditions.

Catheterization↗
PubMed1990

Pancreatic carcinoma developing in chronic pancreatitis: a report of four cases.

Although chronic pancreatitis microscopically surrounding pancreatic carcinoma is common, cancer developing in chronic pancreatitis has rarely been shown. We present four such cases seen between 1983 and 1988. All were male, mean age 56.7 years, and all had had previous surgery for complications of chronic pancreatitis (two a pancreatectomy, two a bypass). Chronic pancreatitis was caused by alcohol in three cases, and calcification was present in three. The delay between chronic pancreatitis and pancreatic carcinoma was 2 to 10 years, and in all, pancreatic carcinoma was at an advanced state, with post-surgical survival of 1.5 to 6 months. CA 19.9 level was very high in the three cases in which it was measured. That pancreatic carcinoma is more frequent in populations with chronic pancreatitis, occurring later in life than pancreatic carcinoma that has no coexisting chronic pancreatitis (sixth decade vs. fifth), often with intermediate histology, argues for chronic pancreatitis degenerating into pancreatic carcinoma rather than for a common toxic etiology. Pancreatic carcinoma occurs particularly in calcified chronic pancreatitis, and diagnosis is frequently quite late, due to the non-specificity of symptoms vs. chronic pancreatitis. Delay of appearance is variable, and previous surgery and histological examination excludes obvious coexisting pancreatic carcinoma. Aggressive surgery appears justified if needed for chronic pancreatitis, and chronic pancreatitis should be carefully followed, probably by serial CA 19.9 determinations and guided percutaneous fine needle biopsies when elevated, or when new symptoms are present in chronic pancreatitis.

Adenocarcinoma↗