[Present problems in school health].
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Biomedical subjects
Publications and source records attributed to G Grossmann.
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After a literature survey about problems of the infectious hospitalism in obstetrical departments it is reported about own examinations in nine clinics. The results of the general hygienic and microbiological studies are discussed, conclusions are being drawn.
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Rats were injected with paraquat, 35 mg/kg, and killed 8 or 12 hours later. Electron microscopic studies of the lungs revealed degenerative changes in alveolar epithelium and alveolar capillary endothelium after 8 hours. After 12 hours, the alveolar lining layer was contaminated with cellular debris from disintegrating alveolar epithelium. This contamination is probably responsible for the inactivation of lung surfactant that can be demonstrated in early stages of experimental paraquat poisoning.
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The authors studied the effects of liquid starter cultures on the survival of pathogenic germs. It was found that the foreign bacteria tested differed in growth limitation which is obviously dependent on acidity and the amount of lactic acid produced by fermentation. Since the pathogenic bacteria differ in the ability to survive, it is imperative to observe strict hygienic measures in preparing starter cultures and to use absolutely sterile monocultures for raw sausage ageing.
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Light and electron microscopic studies of lungs from fullterm newborn rabbits, 0-24 hours after birth, revealed a patchy alveolar air expansion during the first few hours of extra-uterine life. Fairly uniform aeration of alveoli was noted 6-24 hours after birth but minor "unexpanded" areas were still present after 24 hours. In the fetal pulmonary fluid as well as in the alveolar lining layer formed after the onset of breathing there are multiple large phospholipid complexes, and a discontinuous multilamellar surface film can be demonstrated in some alveoli from 2 hours after birth. Apparently, the neonatal adaptation of the rabbit lung is a protracted process, not even complete at the age of 24 hours.
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