Search PubMed⌕ Search

Biomedical subjects

G Gross

Publications and source records attributed to G Gross.

At least 289 records · Page 16Linked to original sources

[Late schizophrenia (author's transl)].

The designation "late schizophrenia" is used with reference to M. Bleuler. Of 502 cases of schizophrenia admitted to the mental hospital of the university of Bonn from 1945-1959 and later catamnestically examined, 14% were taken ill after age 40. Including the deceased, the percentage increases to 17.1 (110 of 644 cases). The onset of disturbance could be ascertained with 50% occurring equally between age 40-44 and age 45-59. Late schizophrenia became manifest after age 50 in 24. 3% and in 3.1% after age 60. The average period of observation was 17.8 years, and 20.7 years including prodromes. In 42.8% prodromes and/or signs in advance could be traced. Females predominated (64.3%). Syntonic personalities were markedly more frequent (49.3%), psychopathic primary personalities less frequent than in other schizophrenias in the first half of life. With regard to premorbid intelligence or hereditability no differences could be found. Psychic-reactive actuation (31.9%) was not significantly more frequent than in the group as a whole (25%). Not even by social factors (social class of parental family, bachelorhood rate, childlessness, and late marriage) could late schizophrenia be reliably distinguished from other schizophrenias. The quota of initially dominating paranoid-hallucinatory (55.4%) and paranoid syndromes (23.2%) is markedly higher than in schizophrenia of the first half of life, depressive moods (47.1%) and coenaesthesias (64.3%) less frequent. The final prognosis is - especially for women - more favorable, the rate of full remissions amounting 30%; 35% showed remissions to slight pure residual symptoms. All types of schizophrenic courses also occur in late schizophrenia; monophasic types are significantly more frequent, the two most prognostically unfavorable types are significantly rarer than in the group as a whole. The rate of social reintegration is with 64.3% higher and that of permanent hospitalization 10% lower than in the group as a whole. In view of the identity of late schizophrenia with all other schizophrenias, the same principles have to be applied to therapy and rehabilitation.

Adult↗

A long-term follow-up study of schizophrenia: psychiatric course of illness and prognosis.

A systematic psychiatric follow-up study of 502 schizophrenics was carried out using the same well-defined criteria to evaluate the patients throughout the investigation. After an average course of disease of 22.4 years, 22.1% of the patients showed complete psychopathological remission, 43.2% had non-characteristic types of remission and 34.7% suffered from characteristic schizophrenic deficiency syndromes. At the time of the last follow-up investigation, 86.7% of the patients were living at home, while 13.3% were permanently hospitalized. Of the entire sample, 55.9% were found to be "socially recovered". Higher education, psychoreactive provocation, depressive traits, perception of delusions, catatonic agitation, non-characteristic thought disorders and symptoms of depersonalization at the onset of the illness tended to carry with them a favorable prognosis. On the other hand, low intelligence, abnormal primary personality, premorbid disturbances in social behavior, broken homes, prolonged prodromal stages, pneumoence-phalographically measurable atrophic or dysplastic changes in the brain ventricles as well as somatic and auditory hallucinations and predominance of hebephrenic symptoms at the onset of the illness tended to lead to an unfavorable prognosis. The principle of the basic reversibility of typical schizophrenic symptoms and the extensive irreversibility of the non-characteristic defect is important for the psychopathological and social long-term prognosis.

Adolescent↗