Biomedical subjects

G Grosdidier

Publications and source records attributed to G Grosdidier.

11 recordsLinked to original sources

PubMed1992

[Value of limited resections in the surgical treatment of lung cancers].

From 1969 to 1990, 88 limited lung resections were performed for the treatment of malignant lung tumours. These operations consisted of 73 typical resections (29 segmentectomies, 15 bisegmentectomies, 23 middle lobectomies, 6 lingulectomies) and 15 atypical resections. In 15 cases, they were completed by lymph node dissection. These operations were performed in patients with a mean age of 55.8 years (range: 24 to 76). The ventilatory functional status contraindicated wider resection in only 7 cases. The immediate postoperative mortality (7 cases, i.e. 8%) and the postoperative complications observed in 29.6% of cases were higher than those observed after wide resections, but do not constitute a specific argument in the indication for partial resection. Histological examination of the operative specimens revealed 80 primary lung cancers (42 squamous carcinomas, 28 adenocarcinomas, 8 anaplastic and unclassifiable tumours, 1 bronchiolo-alveolar tumour and 1 malignant carcinoid tumour). The primary nature of the tumour could not be definitely confirmed in the other 8 patients (history of head and neck neoplasm in 7 cases and bladder carcinoma in 1 case). The survival according to TNM stage, histological nature of the tumour, positivity of the resection margins and intraoperative tumour effraction was identical to that associated with lobectomies.

Adenocarcinoma↗

PubMed1992

[Resection of lung neoplasm in patients aged 70 years and over. Apropos of a series of 193 resections].

Lung cancer in the elderly is an active cancer. Due to the poor tolerance of radiotherapy and chemotherapy, and the ever increasing life expectancy of patients over the age of 70 years, surgery remains the treatment of choice for these lesions. We report a series of 193 patients over the age of 70 years, the high postoperative mortality of 19% during the first month was counterbalanced by a 5-year survival of more than 20%. The criteria of operability must be rigorous and based on objective elements, especially lung function and the patient's good psychological state.

Adenocarcinoma↗

PubMed1991

Anatomical basis of the anterior vertebral graft using a pediculated rib.

The rib is frequently used as a bone graft in the surgery of the anterior spine. The advantage of the rib is that it is easily used as a pediculated vascularized graft when it is transferred to the anterior vertebrae. The average length of the pedicle is over 5 cm for the ribs number 3 to 10. Their useful length of bone is 12 cm. With this technique fusion of 4 to 6 lumbar or thoracic vertebrae is possible.

Cadaver↗

PubMed1991

[Contribution of a 3% solution of boric acid in the treatment of deep wounds with loss of substance].

The correct application of antiseptics to major surgical wounds must comply with appropriate protocols. Compliance with the protocol established by the CHRU of Nancy was evaluated by means of a questionnaire assessing the understanding of the protocol by the nursing staff and by a survey in the wards in which it was applied. The defects observed cannot be explained by a lack of efficacy for superficial wounds and deep wounds, as a randomised study of 42 wounds demonstrated the superiority of the protocol in relation to the use of another product which is widely used in the wards. In contrast, for deep wounds with loss of substance, the proposed protocol does not always achieve therapeutic success. This finding has led the authors to propose the use of a 3% boric acid solution based on a case-control study which demonstrated a significantly superior efficacy. All of the epidemiological and clinical elements are summarised in order to demonstrate the solid basis for compliance with antiseptic protocols of surgical wounds which can only be beneficial in terms of therapeutic success, length of hospital stay and cost savings.

Anti-Infective Agents, Local↗

PubMed1991

[Pulmonary metastasis of a dermatofibrosarcoma].

Progressive and recurrent dermatofibrosarcoma, described by Darier and Ferrand in 1924, is a fibrous skin tumour with essentially local malignancy. The authors report a case with pulmonary metastasis, a rare event as only 13 cases of visceral metastases have been reported in the literature. The clinical course of this case was favourable (follow-up of 5 years), in contrast with the usually pejorative nature of metastatic disease (death after several months to one year following the discovery of the first metastasis).

Fibrosarcoma↗

PubMed1990

[Plastic surgery of the thoracic wall (malformations and tumors) using a sliding splint-stapler].

Chest wall instability, created surgically by correction of a chest deformity (funnel chest or, more rarely, pigeon chest) or by resection of a tumour of the chest wall, is serious as it can jeopardize the immediate vital prognosis because of paradoxical respiration and, in the long term, the functional and aesthetic prognosis due to progressive impaction of the unstable segment of the wall. The polyvalent and adaptable material which we have developed (sliding splint-staple) and which we also use in thoracic traumatology (thoracic flaps), has allowed us to perform audacious corrections for deformities or wide resections for tumours since 1980. We have used this material on 13 occasions for contention after sternochrondroplasty, with an excellent result in each case both in terms of the immediate stability and in terms of the aesthetic result. The sliding splint-staples, generally two, are placed in staggered positions behind the sternum (11 cases--funnel chest) or in front of the sternum (2 cases--pigeon chest). The material is left in place for at least one year. We have used this material on 8 occasions after various tumour resections: 3 times after subtotal resection of the sternochrondral breastplate and 5 times after lateral or anterolateral resection removing at least 2 ribs.

Adult↗

PubMed1979

Fatal peritonitis.

We analysed 117 cases of peritonitis in children. They were divided into two groups: -- Newborn and very young infants with peritonitis. -- Older children with peritonitis. The different causes in every group were studied, and it was attempted to find the particular criteria for each cause. The mortality in newborn and young infants is high, but resuscitation methods and appropriate surgical therapy are giving encouraging results. In older children the mortality from peritonitis is low and more or less resembles that in adults.

Adolescent↗

PubMed1979

[Rupture of the extensor apparatus of the knee; 45 cases].

The authors describe 45 cases of rupture of the extensor apparatus of the knee (excluding fracture of the patella). Some new ideas are put forward concerning the frequent cause by road accidents and the contribution of certain predisposing features which cause degenerative changes of the tendon. Operation was performed in all cases. The extensor apparatus was reconstructed by suture, cerclage or reinsertion, together with the use of procedures described by Mac Laughlin and Scuderi. The results are presented in detail. 90% are very good or good but complications during operation or in the post operative phase were frequent and occurred in 27% of the cases.

Accidents, Traffic↗

PubMed1978

[Anatomical and embryological study of a case of bladder exstrophy with duplication of the urethra].

An exceptional case of a double urethra associated with an extrophied bladder in a neonate boy is reported. This particular malformation allows an ideal procedure with the recovery of a good continence. After the anatomic study of the anomalies, the authors try to find an embryologic explanation. The usual theories of the development in the cloacal region are discussed. Only the embryologenesis as described by SOLERE can explain this malformation.

Bladder Exstrophy↗

PubMed1978

[Tracheo-bronchial malformation associated with an aberrant left pulmonary artery].

A new case of pulmonary artery sling in a three months old boy is reported. After the sudden death of the patient, a precise anatomic study of the malformation was realized. With a complete cartilaginous ring usual in this malformation, there is a right upper lobe bronchus arising from the trachea above the anomalous vessel. The other anomalies of the tracheobronchial tree are discussed.

Bronchi↗

PubMed1977

[Epidermoid cysts of the mandible (author's transl)].

The authors present three cases of epidermoid cyst of the mandible, one of which had undergone malignant change. These cysts are rare. They are most often situated at the angle of the jaw and present as a deep swelling of the cheek. The only treatment is excision, the authors advising the external approach which gave them the best results.

Aged↗