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Biomedical subjects

G Grippaudo

Publications and source records attributed to G Grippaudo.

4 recordsLinked to original sources
PubMed1990

[Diaphanization. Testing method for endodontic technics].

It's a study about the principal clearing techniques, with a selection of materials and phases of execution. The purpose was to obtain transparency of mineralized structure together with preservation of pulpal contents. From this research a technique has been extracted and positively tested, with great results: a) tridimensional control of alterations pointed out in anatomy after canal preparation; b) measurement of pulpal debris size after instrumentation; c) identification of instruments dark zone; d) measurement of the empty-cleansing capacity of root canal system and the defence from eventual self-made errors, as a result of particular operating techniques, whose comparison is accessible by methodology.

Coloring Agents↗
PubMed1989

[Ultrastructural aspects of the submandibular gland].

The structure of normal human submandibular glands has been studied with the electron microscope. Secretory cells are arranged around a central lumen, and are surrounded by numerous myoepithelial cells, showing tapering process. Intercalated and striated ducts follow secretory units. Striated ducts' cells are characterized by extensive infoldings of the basal plasma membrane, among which numerous mitochondria are aligned. Furthermore, the Authors examine the submandibular gland's innervation.

Humans↗
PubMed1988

Study on tissue concentrations of antibiotics: bacampicillin in gingiva and maxillary bones.

21 patients, whose age ranged from 17 to 60 years and who had not been previously treated with antibiotics or other drugs, received bacampicillin as a perioperative prophylaxis for minor operations in the oral cavity. Four oral doses of bacampicillin were administered: each dose of 800 mg every 12 h, and the last dose was administered 2 h before surgery. To assess bacampicillin serum concentrations two blood samples were collected from each patient: the first sample was obtained 1 h before surgery and the second one during surgery. Together with the second blood sample, small quantities of gingiva and bone were obtained from each patient to also assess the antibiotic concentrations in these tissues (microbiological method). The results show that bacampicillin reaches high concentrations in both the blood and tissues studied by us, and that a direct correspondence exists between blood and gingival and bone tissue concentrations. Furthermore, it should be noted that no postoperative infections developed in our patients. These results lead to the conclusion that bacampicillin appears to be a suitable drug in the therapy of dental infections.

Adolescent↗