Biomedical subjects

G Grandi

Publications and source records attributed to G Grandi.

101 records · Page 6Linked to original sources

PubMedDate not supplied

Malignant mesothelioma of the pleura among seafarers.

BACKGROUND: A large amount of data indicates that seafarers are at risk for asbestos disease. OBJECTIVES: To trace the outlines of pleural mesothelioma among seafarers. METHODS: Pleural mesotheliomas diagnosed among seamen in the Trieste-Monfalcone area, Italy, in the period 1973-2003, were reviewed. RESULTS: The series comprised 50 men aged between 53 and 91 years (mean age 75.7 years). The diagnosis of mesothelioma was confirmed by necropsy in 38 cases. The patients had served in the Italian Navy (24 persons), in the merchant navy (17 persons), or in both (9 persons). The trades were various including engine room as well as deck personnel. Asbestos bodies were detected on routine lung sections in 55% of the necropsy cases. Asbestos bodies isolated from the lungs in three cases ranged between 2100 and 7000 bodies per gram of dried tissue. Latency periods ranged between 33 and 72 years (mean 56.1 years). CONCLUSIONS: When compared with shipyard workers, the seamen with mesothelioma show signs of less intense exposure to asbestos, and longer latency periods. Mesothelioma in seamen should be considered as an occupational disease.

Age Factors↗

PubMedDate not supplied

[Importance of oral rehydration in acute infantile diarrhea. Comparison of 2 rehydration solutions].

Oral rehydration therapy has gained worldwide acceptance as the standard treatment for acute diarrhoeal diseases in infants and children. Besides the high sodium glucose-electrolyte solution based on the WHO/UNICEF recommendations, many diverse formulations of oral rehydration solutions (ORS) have withstood the trial of prolonged clinical use, their main differences concerning the concentration of sodium, the choice of the glycidic component, the use of bicarbonate as buffer or its substitution with acetate or citrate. It was recently hypothesized that glucose polymers-containing ORS markedly improve the intestinal sodium/glucose cotransport by delivering glucose at its critical site on the luminal villous membrane and therefore diminish stool output and duration of the diarrhoea. To investigate this hypothesis, the efficacies of two marketed ORS (table I), one containing sucrose and maltodextrin (solution A) and the other containing glucose (solution B) were compared. The study group comprised 13 infants and toddlers, 1 to 18 months old, who presented with acute diarrhea; 5 were males and 8 females; 7 were randomly allocated to receive solution A (Group A), 6 solution B (Group B). There were no significant differences between the groups in age, sex, causation of diarrhea or severity of dehydration before receiving ORS. Both groups showed a satisfactory response to 24 hours of treatment with either ORS, but a significantly lower stool output (number and global weight of stools) and higher blood glucose and bicarbonate levels were detected in group A (table II).(ABSTRACT TRUNCATED AT 250 WORDS)

Diarrhea, Infantile↗

PubMedDate not supplied

[Bacterial meningitis. Study from 1970 to 1988 at the Regina Margherita Children's Hospital in Turin].

From 1970 to 1988, 330 cases of bacterial meningitis were diagnosed at the Children's Hospital Regina Margherita of Turin. Neisseria meningitidis was the most frequent cause of bacterial meningitis (45%); meningitis caused by Haemophilus influenzae increased from 4% in 1970-1983 to 19% in 1984-1988, and meningitis with pathogen unknown decreased from 28% in 1970-1983 to 7% in 1984-1988. The neonatal meningitis in 1984-1988 were caused by Streptococcus B in 90% of cases.

Adolescent↗

PubMedDate not supplied

[Basal cell epithelioma of the lip. Analysis of 42 cases].

Basal cell epithelioma of the lip. An analysis of 42 cases. The authors carried out a histopathological and epidemiological study of 42 basal cell epitheliomas of the lip. Both sexes were equally affected (male to female ratio 0.9:1) but the females were significantly older than the males (mean age: 70.7 years vs 62.3 years respectively). The incidence in the province of Trieste was 1.44%... for males and 1.46%... for females. More than 80% of the lesions (35 cases) consisted in solid forms, but there were also 4 cheratotic basal cell epitheliomas, 1 fibrosing epithelioma and 1 basosquamous epithelioma. In 2 of the males there was a recurrence a year after the surgical exeresis and in 6 cases another epithelioma was synchronous or metachronous to the lip epithelioma. Despite the fact that in 3 cases invasion of the muscular wall was noted and in another case the neoplasm had infiltrated and eroded the left nostril and the lower part of the septum, no patient died from the tumour nor were any metastasis observed.

Aged↗

PubMedDate not supplied