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Biomedical subjects

G Goeckenjan

Publications and source records attributed to G Goeckenjan.

52 records · Page 3Linked to original sources
PubMed1978

Problems of continuous Pa, O2 monitoring by means of indwelling intra-arterial electrodes.

Continuous monitoring of intra-arterial PO2 has many advantages in intensive care. However, there are some problems which have prevented the routine use of this method until now. A commercially available polarographic oxygen electrode was tested in vitro. Continuous PO2 monitoring was performed in vivo in 63 adult patients. The electrode is suitable for intensive care with regard to handling, dimensions, biocompatibility, mechanical stability, electrical safety, sensitivity, flow dependency, response time and costs. It should be improved with regard to the instability of the measuring properties and its non-linearity in hyperoxia. Serious complications of continuous PO2 monitoring were not observed. In view of the specific properties of the polarographic electrode and the contraindications of arterial cannulation, the continuous intra-arterial PO2 measurement has proved to be a valuable, safe and simple technique of monitoring, especially for short-term changes of arterial PO2.

Adolescent↗
PubMed1977

Relation of transcutaneous to arterial pO2 in hypoxaemia, normoxaemia and hyperoxaemia. Investigations in adults with normal circulation and in patients with circulatory insufficiency.

The transcutaneous oxygen tension was monitored continuously by a heated cutaneous polarographic electrode in 7 adult intensive care patients, 12 patients without circulatory insufficiency, and 5 healthy volunteers, Arterial pO2 values were varied from hypoxaemia to normoxaemia and hyperoxaemia by variations of the inspired oxygen concentration. In normal volunteers and in patients without circulatory failure, transcutaneous pO2 indicated on an average about 81-92% of the arterial pO2 in normoxaemia and hyperoxaemia with a correlation coefficient of 0.97. In hypoxaemia there was an over-proportional decrease of the transcutaneous pO2 to a mean value of 44% fo the arterial pO2. In one case the transcutaneous pO2 reproducibly dropped to zero at paO2 values of 41 respectively 38 mm Hg (5.5 respectively 5.1 kPa). In intensive care patients the transcutaneous pO2 values were considerably lower than the paO2 values. There was no constant transcutaneous to arterial pO2 ration in most of the intensive care patients at different pO2 levels. In adults without disturbance of peripheral perfusion paO2 can be predicted with satisfactory accuracy from transcutaneous pO2 values in normoxaemia and in hyperoxaemia. In hypoxaemia and in circulatory insufficiency, the transcutaneous pO2 is only an indicator of the trend of the arterial pO2. Under these conditions it does not allow a quantitative estimate of paO2 changes.

Adult↗
PubMed1976

[Continuous monitoring of pO2 by means of intravascular indwelling oxygen electrodes (author's transl)].

Two intravascular oxygen electrodes (of the International Biophysics Corporation and Roche) were tested in vitro and in long-term monitoring of arterial oxygen partial pressure in 19 patients. There were no complications. Both electrodes proved suitable for use for monitoring in an intensive-care situation. But both could still be improved by having greater stability and a shorter response time. Some of the indications for continuous monitoring of pO2 are mentioned: incipient respiratory failure, shock-lung, pulmonary oedema, and artificial ventilation. Haemorrhagic diatheses and arterial occlusive disease are contra-indications to its use.

Arteries↗