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Biomedical subjects

G Gjurić

Publications and source records attributed to G Gjurić.

At least 19 recordsLinked to original sources
PubMed1994

Thyroid diseases in a school population with thyromegaly.

A survey of 5462 schoolchildren was conducted for signs of thyroid disease in the seaside region of Sibenik, Croatia. In this region, salt is regularly iodised with 0.01% potassium iodide. Thyromegaly was found in 152 children (2.8%). The most common disorder was simple goitre, which was established in 126 of these, 12 boys and 114 girls (combined prevalence of 2.3%, and of 0.45% in boys and 4.07% in girls). Juvenile autoimmune thyroiditis was found in 19 of the children (prevalence 0.35%), with a female:male sex ratio of 8:1. Diagnosis was confirmed in all cases by fine needle biopsy. Thyroglobulin antibodies were detected in all 19 of the patients with juvenile autoimmune thyroiditis, but microsomal antibodies in only eight. Three patients had decreased concentrations of thyroxine and raised concentrations of thyroid stimulating hormone (TSH), one of these also with clinical hypothyroidism. Raised concentrations of TSH but with normal triiodothyronine and thyroxine were seen in two patients. Graves' disease was diagnosed in four children, three girls and one boy (combined 0.07%). Thyroid nodules were identified in three children (0.055%; two benign adenomas and one cyst). Only seven of the 152 patients with thyromegaly (three with hyperthyroidism and four with simple goitre) had previously sought medical advice, which points to the need for careful thyroid examination of apparently healthy children even in regions where the regular iodide intake is assumed to be sufficient.

Adolescent↗
PubMed1994

Ureaplasma urealyticum osteomyelitis in a very low birth weight infant.

We are reporting on a very low birth weight male infant with osteomyelitis of the right femur during blood stream infection with Ureaplasma urealyticum. After previously recognized pulmonary and central nervous system infections, our case description link U. urealyticum to bone disease, widening the spectrum of pathologic conditions in neonates due to this agents.

Humans↗
PubMed1993

Ureaplasma urealyticum infection in newborns: three case reports.

We report three newborns with different manifestations of Ureaplasma urealyticum infection; a term newborn with acute neonatal pneumonia and two very low birth weight infants with bronchopulmonary dysplasia and osteomyelitis of the femur, respectively. The association of U. urealyticum with acute and chronic respiratory disease in term and preterm newborns has recently been reported. Our two cases are similar to other case reports from the literature, but we were unable to find any previous reports of osteomyelitis due to U. urealyticum in the premature babies. Isolation of U. urealyticum in pure culture from the blood was considered to be related to local infection in all three patients. All patients were cured by erythromycin.

Bronchopulmonary Dysplasia↗
PubMed1990

Screening of newborns for congenital hypothyroidism in Croatia--organization and first results.

In 1985 a newborn screening programme for the detection of congenital hypothyreosis was introduced in Croatia in addition to the already existing one for phenylketonuria. The paper delineates the organization of the screening programme, the method used, and the first results. Clinical manifestations, somatic and mental development, as well as laboratory findings of the first eleven children with congenial hypothyroidism detected by the screening programme and followed-up regularly are presented in more detail.

Congenital Hypothyroidism↗
PubMed1989

[Primum non nocere--what does it mean in medicine today?].

The study analyzes bioethical principle of Primum non nocere and its importance and value in modern medicine. The criterion of maleficence for a patient, is defined in its real and ethical, individual, general and time contexts. The relation of ethical postulates of non-maleficence and beneficence and their correlation have been studied. The attention has been drawn to the inadequacy of isolated criterion of causing damage (non nocere) to secure benefit for a patient. The study expresses the necessity and obligation of medicine to estimate scientifically old and new perceptions and applies them to a patient, consonant with bioethical principles.

Ethics, Medical↗
PubMed1982

Plasma renin activity and plasma aldosterone concentration in infants with various potassium intakes.

Plasma renin activity (PRA) and aldosterone concentration (PA) were measured in 20 healthy infants from 1 to 12 months of age during normal (3.03 mmol/kg/d) and high (5.20 mmol/kg/d) potassium intake. PRA did not change between regimes. PA rose significantly from 618 pg/ml during normal to 1136 pg/ml during high potassium intake. It is concluded that the potassium intake should be taken into consideration when studying plasma aldosterone in infancy.

Aldosterone↗
PubMed1979

Plasma renin activity and plasma aldosterone concentration in infants with various sodium intakes.

Plasma renin activity (PRA) and plasma aldosterone concentration (PA) were measured in 20 healthy infants 2-12 months of age, after taking a commercial modified cow's milk formula with 8.2 mmol/l sodium for at least five days, and after at least five days on a home-made, undiluted acidified cow's milk formula with 12.6 mmol/l sodium. The mean sodium intakes were 1.20 and 1.87 mmol/kg of body weight per day respectively. The arithmetic means for the corresponding PRA were 6.16 and 1.08 ng/ml . h (difference not significant) and the corresponding arithmetic means for PA were 603 and 355 pg/ml, the difference being highly significant (P less than 0.01). It is concluded that one has to consider the sodium intake in the milk formula when studying plasma aldosterone in infancy.

Aldosterone↗
PubMedDate not supplied

Haplotype distribution and mutations at the PAH locus in Croatia.

Restriction fragment length polymorphism (RFLP) haplotypes and mutations at the phenylalanine hydroxylase (PAH) locus have been studied in 25 unrelated families from Croatia. The results of RFLP analysis demonstrated that 80% of the mutant alleles were associated with three haplotypes (1, 2 and 4). Eight mutations were detected on the background of six mutant haplotypes, comprising 68% of phenylketonuria (PKU) alleles in Croatia. The mutation in codon 408 was most frequent, as was the haplotype 2 allele with which it was associated. These data are in accordance with formerly published population genetic analyses at the PAH locus, and with studies revealing the molecular basis of the phenotypic heterogeneity of PKU. The codon 281 mutation was more frequent in Croatia than previously observed in other populations.

Alleles↗
PubMedDate not supplied

[Peace!].

Explore the source record for details and available documents.

Croatia↗
PubMedDate not supplied

[The status of care of abused and neglected children in Zagreb at the end of the 20th century].

In this paper, the data on some medical, social and legal aspects of abuse and/or neglect of children in Zagreb are presented which, at least, partially illustrate this societies' care of mistreated children at the end of the 20th century. We reviewed questionnaires that were administered to 44 health institutions involved in the childrens' health control and/or treatment and to 14 social work services and analyzed cases of child mistreatment reported to the Zagreb Public Prosecution Office and final court judgements for 1987 to 1988. We conclude that all these institutions encounter cases of child abuse and/or neglect but that medical institutions identify only 10% of cases detected by social work services and that judicial system sentences with imprisonment about 30% of abusers. Underdetection of child mistreatment in Zagreb, in addition to poor coordination of services, are the possible reasons for insufficient concern for these children. Up to now, only mass media and scientific publications have spoken more loudly about this problem. The authors emphasize the need and obligation of all those professionals concerned with children and of the entire community to undertake relevant measures to protect abused and/or neglected children.

Child↗
PubMedDate not supplied

[Child abuse and neglect. I].

In this review, published in two parts, the medical social and legal aspects of child abuse and neglect are assessed. The aim of this paper was to get all the physicians involved in the care of children more thoroughly acquainted with the extent, manifestations and management of abused and/or neglected children. The necessity of an organized multidisciplinary approach to this serious medical and social problem is also stressed.

Child↗
PubMedDate not supplied

[Child abuse and neglect. II].

In this review, published in two parts, the medical social and legal aspects of child abuse and neglect are assessed. The aim of this paper was to get all the physicians involved in the care of children more thoroughly acquainted with the extent, manifestations and management of abused and or neglected children. The necessity of an organised multidisciplinary approach to this serious medical and social problem iz also stressed.

Child↗
PubMedDate not supplied

[Infant health care].

This paper presents some aspects of the infant health care in Croatia in the last decade of the 20th century. Neonatal and postneonatal declining of mortality, shift of the infant mortality into the first month of life and causes of mortality in the first and later months to the end of the first year of life are shown. The structure of health care on primary and secondary level is presented. Stressed are the problems of delivery without professional help, care of the newborn after hospital discharge, sine-medical mortality of infants and infants death from accidents and injuries. The author urges for further development of health care system for infants and infants death from accidents and injuries. The author urges for further development of health care system for infants to ensure their survival and better quality of life.

Child Health Services↗