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Biomedical subjects

G Giusti

Publications and source records attributed to G Giusti.

At least 109 records · Page 6Linked to original sources
PubMed1975

Activation energy, relative substrate specificity and optimum pH of guanase from humanrat, mouse and guinea pig sera and tissues.

Some properties of serum and tissue guanase from man, rat, mouse and guinea pig have been studied. Serum guanase differs from tissue guanase in activation energy in the human species and in guinea pig. The mouse and rat brain enzyme differs from the liver and kidney enzyme. The guanase of each species differs from the enzyme of the other species in one or more properties.

Acute Disease↗
PubMed1975

Hemostatic abnormalities in chronic aggressive hepatitis and liver cirrhosis.

Hemostatic defects of chronic aggressive hepatitis (CAH), 25 cases, and of liver cirrhosis, 20 cases, were investigated. The following assays were performed: liver function tests, thromboelastogram, prothrombin time (PT), partial thromboplastin time (PTT), factors I, II, V, X, XIII, euglobulin lysis time, fibrinogen degradation products (FDP), platelet count, morphology and agglutinability. High incidence of hemostatic defects was present in both groups. Thromboelastogram, PTT, prothrombin and qualitative platelet abnormalities were most common. On the whole, severity of hemostatic alterations in cirrhosis was more pronounced than that found in CAH, FDPs were increased in more than 50% of the CAH cases and only in a few cirrhotic patients. Bleeding occurred more frequently in cirrhosis (55%) than in CAH (4%) and, within the cirrhotic patients' group, it was associated with a more severe thrombocytopenia.

Adult↗
PubMed1975

Differential diagnosis between benign and malignant biliary tract obstruction: discriminative usefulness of some clinical and laboratory data.

The data of 26 patients with obstructive jaundice caused by biliary tract stones were compared to those of patients with malignant obstructive jaundice in order to evaluate the diagnostic effectiveness of some laboratory tests in the differential diagnosis between these two conditions. The Fisher's discriminant analysis was employed. The combined evaluation of serum albumin and haptoglobin appeared to have the most satisfactory discriminative effectiveness, yielding a 54% rate of correct diagnosis, with a safety margin of 95%.

Alanine Transaminase↗