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Biomedical subjects

G Gillespie

Publications and source records attributed to G Gillespie.

At least 127 records · Page 7Linked to original sources
PubMed1975

Prophylactic oral antimicrobial agents in elective colonic surgery. A controlled trial.

A controlled trial has been carried out in 50 patients undergoing elective colonic surgery to assess the efficacy of prophylactic oral metronidazole specifically directed against anaerobic colonic microflora in combination with kanamycin to reduce the aerobic flora. A control group received dietary and mechanical preparation alone. A significant reduction of both aerobic and anaerobic colonic microflora was achieved in the group receiving prophylactic antimicrobial agents, and this was reflected in a significant reduction in postoperative wound infections. 1 control patient died from Bacteroides septicaemia. No toxic or other side-effects from this prophylactic regimen occurred in this trial.

Administration, Oral↗
PubMed1975

Results of surgery for Crohn's disease in the Glasgow region, 1961-70.

During the period 1961-70, 283 patients in the Glasgow region have been studied with regard to the outcome of 418 surgical procedures performed for Crohn's disease. Resection was followed by an overall recurrence rate of 33 per cent, but in disease confined to the large bowel the rate was 18 per cent. Exploratory operations and bypass procedures were followed by a recurrence rate of 70 per cent. Evidence is provided that recurrence following bypass procedures for small bowel disease and ileocolitis occurs at a later stage than after exploratory operations alone. By the end of the study 77 per cent of patients in this series had required one or more resections.

Crohn Disease↗
PubMed1975

Epidemiological aspects of Crohn's disease in Clydesdale 1961-1970.

A retrospective study of Crohn's disease has been carried out in Clydesdale covering the decade 1961-1970. Three hundred and fifty-seven patients had acceptable evidence of either acute ileitis or of chronic granulomatous bowel disease. Of those fulfilling the criteria for inclusion in the study of chronic disease, 95% had accurate pathological and/or operative documentation of the lesions. Overall, females outnumbered males by 1-6:1 but colonic disease alone tended to affect females, particularly those over the age of 50. The annual incidence of all forms of the chronic disease in both sexes has increased during the decade, but diagnosis of colonic disease alone increased two-fold in the latter half of the study.

Acute Disease↗
PubMed1974

Arterial surgery in intermittent claudication.

The results of a survey of 302 operations in 277 patients during 1959-70 are presented, and an additional 69 operations during 1971 are included in the mortality figures. Operative mortality (1968-71) was 0.9% in 113 aortoiliac operations and nil in 96 femoropopliteal operations.Immediate patency rates on dismissal from hospital exceeded 95%, and the five-year patency rate for aortoiliac operations was just over 70% and for femoropopliteal operations 60%.

Adult↗