Biomedical subjects
Publications and source records attributed to G Gilardi.
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The authors considered sulprostone effects, PGE2 synthetic derivative, on the hematic loss during laparomyomectomy. This drug is been used by intravenous way during the operation in 84 patients affected with uterine myomatosis. The effectiveness and tolerance of the drug is thus evident in the reduction of the hematic intraoperative loss.
The authors report a case of a 46-year-old woman who was checked by integrated ultrasound examination, i.e. transabdominal and transvaginal, and by abdominopelvic CAT. The examinations, ascertained the presence of a probably malignant, voluminous, ovarian, multilobate abdominopelvic neoplasia. On opening the belly, it was found that the tumefaction was a voluminous, pedunculate uterine myofibroma in clusters starting from the rear isthmian wall while the adnexa were normal. The histological examination confirmed that it was a "fibromyoma in hyaline and cystic degeneration". The authors conclude that although the image diagnostics has reached an extremely high level of precision, it is not yet possible to make an absolutely certain diagnosis, either on the organ from which a pelvic neoplasia originates or on its biological nature.
Endometrial cancer staging is obtained by the analysis of the surgical-pathological parameters. Therefore, surgery represents the first approach to this neoplasia. Surgical-pathological data analysis informs us of the main prognostic factors and the spread of the disease. On the basis of these findings, the risk of recurrence can be estimated and adjuvant treatments can be planned. A protocol for staging and treatment of endometrial carcinoma has been designed by the authors. After surgery, adjuvant therapy (chemotherapy or radiotherapy or the two modalities combined) is suggested by analysis of the prognostic factors. The aim of the protocol is to increase the relapse-free survival and to improve the quality of life of endometrial cancer patients.