[Experimental research on homotransplants of kidney. II. Technical data on the subject of bilateral renal transplants in bloc].
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Biomedical subjects
Publications and source records attributed to G Gibertini.
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An experimental model of pulmonary hypertension was obtained in the dog implanting the left main pulmonary artery in the descending thoracic aorta. The main histological lesions consisted in an increased muscularity of the pulmonary artery itself and of its lobar branches.
An experimental model of acute pulmonary edema was obtained in the rat, with over-infusion of normal saline and of plasma: histology demonstrated essential differences between edema from crystalloids, developed in the interstitial space, and that from colloids, affecting the alveoli.
The authors describe two cases of pseudomyxoma peritonei, one of which with a lengthy clinical course and the other with a rapidly fatal outcome. The clinical picture in pseudomyxoma peritonei is associated with a variety of benign or malignant mucus-secreting tumours, mainly originating in the appendix or ovaries. Survival is generally long owing to the lack of visceral invasion or metastases. An accurate prognostic assessment can only be achieved on the basis of identification of the primary tumours and its degree of malignancy.
In course of acute bacterial peritonitis in rats, the authors observed an active role of the macrophages of the spleen, well explaining the important defensive function of this organ against infection.
The authors report a surgical technique for high approach to the common femoral artery, just below the inguinal ligament, which can be useful in cases of difficult dissection of the femoral region or those with diffuse fibrosis or multiple scars. It is also useful when there is a concomitant inguinal hernia to repair.
During acute experimental peritonitis in the rat, the main histological lesions in the liver are represented by venous stasis in the central lobular vein and in the sinusoids; by glycogen mobilization and intracytoplasmic accumulation of triglycerides in the hepatocytes; by activation and hypertrophy of Kupffer's cells.
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Emergency laparoscopy was successfully used in 106 multiple-trauma and often unconscious patients with blunt abdominal traumas. In 40 cases a negative result avoided any subsequent exploratory laparotomy; two false negative were registered, while a diagnosis of retroperitoneal hematoma was possible in 6 cases.
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