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Biomedical subjects

G Ghirardini

Publications and source records attributed to G Ghirardini.

At least 37 records · Page 2Linked to original sources

Long term treatment with nifedipine retard to suppress preterm labour.

Oral nifedipine retard treatment to suppress preterm labour was administered to 8 patients using a new scheme. Treatment started between 28 and 34 weeks of pregnancy and continued until 38-40 weeks. In all cases suppression of premature labour without hospitalization was achieved. No adverse maternal/fetal effects were observed.

Adult↗

The role of transvaginal sonography in chorionic villi sampling.

Vaginosonography has the potential of improving not only accurate diagnosis preceeding chorionic villus sampling but also the sampling procedure itself. The vaginosonographic diagnostic landmarks of early pregnancies are the contact area between the amnion and the chorion, the insertion of the umbilical cord, the yolk sac and the decidua-trophoblast complex. The occurrence of a "Swiss-cheese-pattern" in the latter structure is a strong hint for an unfavourable outcome of early pregnancy. Vaginosonographically guided puncture is a promising approach for chorionic villus biopsy. The punturing facilities are firmly attached to the high resolution vaginal ultrasound probe. Thus, precise ultrasound-guided puncture penetrating the vaginal skin and the uterine wall in the shortest possible distance has become possible.

Adolescent↗

Vaginal agenesis (mayer - rokitansky - küster - hauser syndrome): recent etiopathogenetical and anatomical views.

Congenital absence of uterus and vagina is a picture known as Mayer-Rokitansky-Küster-Hauser syndrome. Six cases are reported and particular attention is devoted to the anatomical pictures, which can be found in typical or atypical form. Discussion on the etiopathogenetical problems, supporting Hauser's hypothesis of an inhibition of the müllerian ducts development by MIF production, allows to consider it as the slightest form of female pseudoermaphroditism. Moreover the terms used to delineate this condition, like "müllerian aplasia", "müllerian ducts aplasia", "müllerian ducts agenesis" and "uterovaginal agenesis" may be misleading and the term of "müllerian dysgenesis syndrome" is proposed.

Fallopian Tubes↗