Search PubMed⌕ Search

Biomedical subjects

G Ghilardi

Publications and source records attributed to G Ghilardi.

At least 73 records · Page 4Linked to original sources
PubMed1989

[Primary mediastinal masses of benign nature. Clinical classification and criteria of therapy].

A consecutive series of 34 primary mediastinal masses of benign origin was operated on since 1970 through 1988. Many diagnostic techniques were performed, including traditional x-ray of the chest, scintigraphy, angiography; in the more recent years CT and NMR took the place of traditional tomography. In selected cases hormonal dosages were of value in clarifying the endocrine activity of the masses. The various diagnostic techniques performed are discussed as well as their effectiveness in the preoperative diagnosis of nature, benign or malignant, of the masses. This cannot be reached with precision without opening the thorax. The detail of the 34 cases is reported. In the light of the recent literature, the absolute need for surgical treatment of any mediastinal masses, even if asymptomatic, is debated. This aggressive surgical approach is the only effective way to establish the histological nature of the mass and, at the same time, to obtain the radical cure of the lesion.

Diagnosis, Differential↗
PubMed1989

[Loco-regional complications in the surgery of the subclavian artery].

Surgical treatment of subclavian artery atherosclerotic lesions has prophylactic significance in the evolution of cerebrovascular insufficiency. Local complications during interventions on subclavian artery are incidentally more significant than cerebral ischemic complications. Among local complications we reported 2 cases of phrenic nerve involvement and 1 case of thoracic duct lesion in a series of 86 operated patients. We never found cerebral ischemic complications in the surgery of subclavian artery atherosclerotic lesions.

Arteriosclerosis↗
PubMed1989

[Endodermal and coelomic mediastinal cysts].

Eight cases of mediastinal cysts of endodermic and celomatic origin were operated on at Istituto di Chirurgia Generale e Cardiovascolare, University of Milano: two were bronchogenic cysts, two enteric and four pericardial. Embryology, morphologic presentation, clinical feature and diagnostic aspects are discussed for each group of cysts. The most modern techniques, radiological or not, available for the preoperative diagnosis are illustrated and the indication to surgical treatment of these benign mediastinal lesions is discussed.

Adult↗
PubMed1989

[Influence of a prior iliofemoral reconstruction on the patency of the femoro-femoral bypass].

A series of 40 femoro-femoral by-pass grafts (FFBG) is presented; these operations were performed from 1978 to 1987 and the follow-up ranged between 6 and 36 months. The subjects were divided retrospectively into two groups, to evaluate the effect of prior iliofemoral reconstructive operations on the long-term patency of the FFBGs. Thirty-four patients (group A) had no previous surgery and 15 (group B) had 23 previous femoral surgical reconstructions. At operation, 34 recipient deep femoral arteries underwent adjunctive TEA (24 out of group A; 10 out of group B) as well as 9 donor limb deep femoral arteries (all out of group A). No donor limb steal phenomenon was recorded in both groups. FFBG occlusion occurred without any statistically significant differences in the groups (A 12%, B 20%) and only in one case a thigh amputation was needed (group B).

Aged↗
PubMed1989

[Postoperative hypertension and hypotension in carotid surgery].

Postoperative changes of blood pressure in carotid artery surgery is frequently observed. The Authors, on the base of a review of the literature and examining their own experience related to a consecutive series of 40 cases verify the incidence of this event. Different modality in the onset of postoperative hypertension and hypotension are evaluated. The risks of neurological complications due to the acute hemodynamic modifications are considered.

Aged↗
PubMed1989

[Mediastinal neoplasms of mesenchymal origin].

A series of 6 mediastinal tumors of mesenchymal origin is presented. This type of tumors is very heterogeneous in its histology, depending on the differentiation of the primary mesenchymal cell. Presenting symptoms are not diagnostic: nevertheless malignant neoplasms are often revealed by vague thoracic pain, while benign masses usually show the tendency to a slow non infiltrating growth accompanied by faint symptoms of mediastinal compression syndrome. Mesotheliomas and liposarcomas are the most frequent malignant neoplasms, while lipomas are the most represented among the benign ones. Preoperative diagnosis is often casual, based on plain X-ray examination of the chest: subsequent thoracic CAT is of utmost advantage, providing the exact definition of the limits of the mass and of its ability to invade visceral and vascular structures of the mediastinum. Lipomas are well identified by CAT because of their characteristic attenuation value. Surgical operation is mandatory, because benign neoplasms can be effectively cured and infiltrating masses correctly staged and identified by histological examination.

Adolescent↗
PubMed1989

[Role of conservative therapy and surgical treatment in disease caused by gastroesophageal reflux].

A series of 82 subjects affected with reflux esophagitis is presented. Gastroesophageal reflux and peptic esophagitis were discovered and staged by contrast meal and endoscopy with biopsy. All patients underwent medical therapy based on drugs affecting gastroesophageal motility and acidity of gastric content: this therapy was administered for three months, then was performed a control endoscopic examination. Endoscopic recovery of esophagitis allowed a long term maintenance therapy, endoscopically controlled every year. When esophagitis persisted, cycles of medical attack therapy, were repeated. surgical operation was performed in 15 cases in which either three cycles of medical therapy failed to improve esophageal lesions, or when endoscopy showed worsening esophagitis.

Adult↗
PubMed1989

[Thymomas non associated with myasthenia gravis. Nosologic aspects and therapeutic correlations].

A series of nine tumors of the thymus gland without myasthenia is presented. Five neoplasms were benign, while four malignant in their biological behaviour and histology. The classification of these neoplasms was possible according to the embryology of the anterosuperior mediastinum and thymus as well as to the macroscopic and histologic appearance of the masses. Based on pathologic considerations thymomas are divided into lymphoepithelial thymomas, carcinomas, primary Hodgkin's disease of the thymus and lymphosarcomas. The variable biological behaviour of these tumors is discussed and the possibilities of surgical treatment are expounded.

Adult↗
PubMed1989

Insulin secretion and glucose tolerance in non-insulin dependent diabetic patients after chronic nifedipine treatment.

The effect of nifedipine 40 mg.day-1 for 3 months on glucose tolerance, insulin and C-peptide secretion after an oral glucose tolerance test (OGTT), intra-venous glucose tolerance test (IVGTT) and glucagon stimulatory test, has been studied in 8 moderately hypertensive women suffering from non-insulin dependent diabetes mellitus (NIDDM). No significant variation in glucose metabolism was noted after nifedipine treatment, except for a slight improvement in insulin secretion after OGTT at the end of the study. There was an increase in cholesterol as a collateral effect.

Blood Glucose↗
PubMed1985

Digital subtraction angiography for preoperative diagnosis of carotid body tumor. Case report.

A case of carotid body tumor preoperatively diagnosed by digital subtraction angiography (DSA) is reported. For the first time to our knowledge, it demonstrates the effectiveness of DSA in the preoperative diagnosis of carotid body tumor. The advantages of this procedure vs. direct angiography are mainly its lower invasiveness and the absence of side- effects secondary to direct intra-arterial administration of contrast dye under general anesthesia.

Adult↗
PubMed1985

Gastrointestinal transit in hyperthyroid patients before and after propranolol treatment.

Mean mouth to cecum transit time determined by the hydrogen breath test after oral lactulose in a group of 10 hyperthyroid patients (nine with regular bowel habit and one with diarrhea) was significantly lower than that observed in 10 euthyroid controls [53 min (SD 15) versus 123 min (SD 12.2), p less than 0.01]. After 5 days of propranolol treatment the patients showed a significant reduction of the heart rate but no modification of transit time [51 min (SD 7.3)].

Adult↗