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Biomedical subjects

G Geserick

Publications and source records attributed to G Geserick.

At least 73 records · Page 4Linked to original sources
PubMed1979

[Quantitative determination of the alpha-feto-protein in the practice of perinatal medicine. 1st communication: the physiology of the alpha-feto-protein and its quantitative proof by means of electrophoresis in antibody containing gel according to Laurell (author's transl)].

The alpha-feto-protein (AFP) ist described on the basis of the available literature; its diagnostic use up to the present is outlined, and an immunological method of its quantitative determination is presented. The results obtained by quantitating the level of AFP in the cord serum of 50 mature newborns (-x = 9,9 mg/100 ml) are in good agreement with other reports.

Birth Weight↗
PubMed1977

[Relationship between haptoglobin types and group G streptococci (author's transl)].

A relationship was found between the haptoglobin types of human sera and the agglutinability of some strains of group G streptococci. Sera with the haptoglobin types Hp 2-2 and Hp 2-1 agglutinate these streptococci to high titers, from 1:200 up to more than 1:6400. On the other hand, the sera with haptoglobin type Hp 1-1 agglutinate not more than up to titers of 1:16 (mostly lower). Out of 102 strains of group G streptococci only 3 showed this characteristic phenomenon. This study was undertaken in order to elucidate whether the Hp 2-2 and Hp 2-1 proteins have antibody activity. Incubation of Hp 2-2 or Hp 2-1 sera with antihaptoglobin antisera or with anti-Hp 2-antiserum did not change the agglutinating activity but the haptoglobin was eliminated from the sera. Absorption of Hp 2-2 and Hp 2-1 sera with these group G streptococci lowered the titers significantly but the haptoglobins are detectable as in the non-absorbed sera. Sera with haptoglobin 1-1 contain an inhibitor. Mixing of Hp 2-2 and Hp 2-1 sera with high agglutinating titers with Hp 1-1 sera (low titers) was followed by a significant decrease of the titer.

Agglutination↗
PubMed1977

[The question of the validity of haptoglobin/G-streptococci relations in nonhuman sera].

The relationship between haptoglobin type and the agglutinability of some group G streptococci, which was observed in humans, could also be demonstrated in animal sera. In humans the haptoglobin type Hp 1-1 is correlated with a lacking or very low agglutinability. Sera of 10 rhesus monkeys showed Hp-type 1-1 and agglutinated the streptococci only to dilutions of the serum up to 1:4. The sera of 48 pigs contained an Hp 1-1 like type and a streptococcus agglutination titer of max. 1:10. Seven ahaptoglobinaemic sera gave the same values. Fifty examined sera of rabbits showed also an Hp 1-1 like pattern and did not agglutinate or in undiluted state only.

Agglutination Tests↗