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Biomedical subjects

G Gell

Publications and source records attributed to G Gell.

At least 37 records · Page 2Linked to original sources

[Computer-assisted tumor documentation, after-care and medical correspondence in radiotherapy].

Without electronic data processing the recording and statistical evaluation of a great number of tumor patients is only hardly possible. A tumor register and follow-up program is described which has been established for radiotherapy during the development of a national tumor register organized at present. This tumor register also serves as a basis for letter-writing to physicians. The software can easily be adapted to the needs of every hospital because a commercial data bank system has been used. The data input and output is carried out over several terminals. The hardware and software system as well as the incorporation of the data bank into the national tumor register are described.

Aftercare↗

[Computer-assisted diagnosis of bone tumors and tumor-like skeletal diseases: critical evaluation of its clinical use].

Thirty-four patients with bone tumours and tumour-like abnormalities of the skeleton, of varying ages, were examined by a computer-aided diagnostic program; the accuracy, clinical usefulness and specific advantages and disadvantages of the program have been evaluated. This was done by two statistical methods, both with showed high accuracy and reliability of the system (97% and 88.2%). In addition to the diagnostic results, the growth rate of the lesion could be estimated. This indicates the biological behaviour of the tumour independently of the histological diagnosis.

Bone Neoplasms↗

[Free programmable image functions (windows) for computer tomography].

Software windows are a flexible and general method for defining arbitrary functions for the mapping of Hounsfield-numbers of CT-scans on to the grey levels of the display image. The method which is illustrated with the aid of a few examples has been implemented on an EMI viewing console.

Brain↗

Predicting lethal outcome after severe head injury -- a computer-assisted analysis of neurological symptoms and laboratory values.

A total number of 58 parameters (laboratory values, neurological symptoms, and vegetative parameters) were evaluated in 150 patients during the first seven days after severe head injury. The patients were divided into two groups, "survivors" and "non-survivors". Eight easily evaluable routine parameters with the most significant differences between the two groups of patients were used for statistical evaluation of a "no survival chance score". These highly indicative parameters are serum osmolarity and urea, blood glucose, total bilirubin, motor reaction to stimuli, body temperature, respiratory activity, and pupil reaction. A "low survival chance limit" was evaluated from each of these parameters by computer analysis. None of the patients in the series survived when three or more of these eight parameters had climbed beyond the limit. So far, the system is able to predict "no survival chances" in 50.8% of the non-survivors some six days prior to death; 80% of these predictions could be made by the fourth day after injury.

Adolescent↗

Calculation of cerebral tissue and cerebrospinal fluid space volumes from computer tomograms.

The volumes of the cerebral tissue, and internal and external cerebrospinal fluid spaces were calculated from the computer tomograms of 28 patients. On the basis of their different absorption coefficients, cerebral tissue and CSF space were outlines and their volumes calculated by computer. The ratio of cerebral tissue volume to CSF space volume was expressed as an index. This correlated well with an objective grading of severity of hydrocephalus. The index in patients without pathology was between 10.5 and 18.4. In cerebral atrophy the index was between 2.1 and 6.7 depending upon the severity. In occlusive hydrocephalus it was between 1.0 and 5.6. The changes in the volume of the CSF space after treatment can easily by demonstrated by appropriate changes in the index.

Adult↗

Azotaemia in severe head injury--central dysregulation or renal failure?

We have investigated serum urea, uric acid, and creatinin crealinine levels in 39 patients with craniocerebral trauma. The most impressive observation was a change in serum urea, which was found significantly increased up to 237 mg% on the seventh day (mean value) after severe injury, and turned out to be of great prognostic value. Patients with a serum urea above 100 mg% did not survive the acute stage. Uric acid and creatinine were only significantly increased in patients with lethal outcomes, the first being elevated by about 300% in the first week, the second remaining normal for four days increasing thereafter. It is concluded from these first data that a hypercatabolic state due to shock, central dysregulation, or both, is responsible for the dissociated behaviour of urea, uric acid and creatinine during the first four days, after which renal failure as a secondary change is shown by the rise in serum creatinine.

Brain↗

[Optimized cross-section determination for treatment planning in radiation therapy (author's transl)].

A true scale cross-section of the body is an indispensable condition for the accuracy of treatment planning in radiation therapy. To this end, ultrasonic or computed tomography may be used. Advantages and disadvantages of these methods are discussed. By summarization of cross-sections from all positions appropriate for treatment the most authentic body contours are obtained as an optimal basis for irradiation.

Anthropometry↗

[Renal osteopathy and bone mineralisation in patients treated with dihydrotachysterol during long term dialysis (author's transl)].

21 hypocalcemic patients on regular hemodialysis were treated for 2 months with 0.2 mg and for a further 2 months with 0.46 mg dihydrotachysterol daily. 8 normocalcemic patients served as a control group. Radiological and radiodensitometric investigations were undertaken in all patients at regular intervals. Slight signs of renal osteopathy with a predominant osteomalacic component could be established in the skeletal X-ray in 55% of all patients. Compared with a healthy collective, all dialysis patients showed a small but significant reduction of bone mineralisation radiodensitometrically before the beginning of treatment. During treatment with dihydrotachysterol, the patients showed a significant demineralisation of the skeleton. In four cases the characteristics of the osteopathy also increased in the skeletal radiography. During the same period of observation, none of the untreated patients showed any change of the bone mineralisation.

Absorptiometry, Photon↗

Experience with the AURA free-text documentation system.

AURA is a free-text system designed to facilitate automatic documentation of radiological reports, with the goal of making the information in the reports accessible for case location, feedback, and statistical evaluation without changing the regular routine of the radiologist. A simple interactive search language makes retrieval easy. Search criteria can be formulated in medical terms and do not require programming ability.

Information Systems↗