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Biomedical subjects

G Garcia

Publications and source records attributed to G Garcia.

136 records · Page 8Linked to original sources
PubMedDate not supplied

Central nervous system myelin deficit in rats exposed to 2,4-dichlorophenoxyacetic acid throughout lactation.

Our results show that 2,4-dichlorophenoxyacetic acid (2,4-D) exposure through mother's milk during the period of rapid myelination (from the 15th to the 25th postnatal days) results in a myelin deficit in the pup's brain and demonstrates the vulnerability of the developing central nervous system (CNS) to 2,4-D. After 100 mg/kg 2,4-D administration to dams, brains of male and female rats show a significant diminution of myelin markers such as monohexosylceramide as well as phospholipids and free fatty acids (FFA) and an increase of cholesteryl esters. Histological studies revealed myelin deficit in some brain regions after 2,4-D treatment. These data indicate that 2,4-D, through the mother's milk, alters the myelination process during a specific postnatal period.

2,4-Dichlorophenoxyacetic Acid↗
PubMedDate not supplied

Post-laparoscopic cholecystectomy bile leak secondary to an accessory duct of Luschka.

Intraperitoneal bile collection following laparoscopic cholecystectomy has been reported to occur in 0.2-2% of cases and appears to be slightly higher than when the open technique is used. When the injuries of the common bile duct, technical problems with the cystic duct, diathermic injuries to the biliary tree, and iatrogenic interruption of congenital anomalous of the biliary tree are excluded, the iatrogenic transaction of the cholecystohepatic ducts commonly known as the 'Ducts of Luschka' should be considered as the cause of the biliary leak. This article reports a case of bile leakage due to an unrecognized division of a large duct of Luschka within the gall bladder fossa during laparoscopic cholecystectomy and reviews clinical diagnosis, radiological confirmation, and the appropriate treatment for this uncommon complication of laparoscopic cholecystectomy.

Adult↗
PubMedDate not supplied

Masculinity and femininity in nursing.

The concept of the "ideal nurse" was rated by 186 undergraduate and graduate nursing students on the 24-item Personal Attributes Questionnaire. PAQ contains independent subscales that measure masculinity and femininity as well as a bipolar subscale in which masculinity and femininity represent opposite endpoints on a single continuum. The ideal nurse was rated as being highly masculine, highly feminine, and midway between masculine and feminine endpoints on the bipolar subscale. Compared to undergraduate females, graduate and male nursing students rated the ideal nurse as being more masculine. Implications of these findings in the field of nursing are discussed.

Adolescent↗
PubMedDate not supplied

Comparative in vitro microradiographic effects of resin-modified and autopolymerizing glass ionomers on demineralization of primary and permanent enamel.

The purpose of this study was to compare in vitro effects of resin-modified and autopolymerizing glass ionomer restorative materials on demineralization of primary and permanent human enamel. Thirty primary and permanent enamel specimens measuring approximately 3 x 4 x 4 mm were sectioned and plano-paralleled before random placement of materials: Photac-Fil, a resin-modified glass ionomer; Ketac-Fil, an autopolymerizing glass ionomer; and Tytin, a silver amalgam. After incubation for twenty-four hours, the samples were pH cycled for eight hours at pH 5.0 and sixteen hours at pH 7.2 for a total of two weeks, all at 37 degrees C. The specimens were then subjected to an artificial caries challenge at pH 5.0 for 196 hours. The specimens were embeded in Epon 812 and incubated at 55 degrees C for thirty-six hours. Microsections were produced from each sample and subjected to microradiography and quantitative microdensitometry. Data on lesion depth and mineral content were analyzed by Two Way ANOVA and Student Newman-Keuls Pairwise Multiple Comparison tests. There were significant differences in lesion depth and mineral content between groups (p < 0.05) and between permanent and primary enamel. This study demonstrates that Photac-Fil and Ketac-Fil prevent in vitro demineralization at varying levels in primary and permanent enamel.

Absorptiometry, Photon↗
PubMedDate not supplied

Effect of a commercial competitive exclusion culture (Preempt) on mortality and horizontal transmission of Salmonella gallinarum in broiler chickens.

A commercial competitive exclusion (CE) culture (PREEMPT) was evaluated for its ability to decrease mortality during the first 10-12 days posthatch resulting from the causative agent of fowl typhoid, Salmonella gallinarum. In the first experiment, chicks provided the CE culture on day of hatch and challenged with 10(5) S. gallinarum on day 3 had a significant decrease in mortality compared with non-CE-treated S. gallinarum-challenged chicks in all four replicates. Mortality for control chicks when averaged across all four replicates was 74% compared with 7.5% for the CE-treated chicks. A second experiment was performed that was designed to measure the efficacy of the CE culture in decreasing the horizontal transmission of this pathogen from infected to uninfected chicks when commingled. Day-of-hatch chicks that were directly infected (seeders) with 10(5) S. gallinarum and provided no CE culture averaged 86% S. gallinarum organ positive and 80% mortality during the first 12 days posthatch across four replicates. Untreated contact (not directly infected) chicks that were commingled with the seeder chicks averaged 84% S. gallinarum organ positive and 54% mortality, and the commingled CE-treated contact chicks (provided CE culture on day of hatch) average 35% S. gallinarum organ positive and 9% mortality during the same time period. These results are of importance to the poultry industry in geographic areas where poultry production is adversely affected by fowl typhoid and indicate that treating newly hatched chicks with this commercial CE culture may be a novel way of decreasing economic losses associated with this highly pathogenic organism.

Animals↗