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Biomedical subjects

G Gandini

Publications and source records attributed to G Gandini.

At least 127 records · Page 7Linked to original sources
PubMed1987

[Magnetic resonance in the study of the adrenal glands].

Current usage of MR in the clinical study of adrenal pathology is assessed with a review of the advantages and limitations of this new imaging technique and a critical analysis of data deriving both from the literature and from personal experience. The possibility of a multiplanar study offered by MR permits a more accurate anatomical-topographical definition of the adrenal masses though it is not yet capable of the tissue characterisation that would diagnose the nature of the lesion, though it can differentiate between inert adenomas and metastases.

Adenoma↗
PubMed1987

[A case of giant lumbar neurinoma].

A rare case of a giant extradural neurinoma of the IV lumbar root with an anterior development and a soft neurological picture is reported. The Authors stress the important role of CT both in the neurinoma diagnosis and in the correct preoperative evaluation of its extension and its relationship with contiguous organs.

Female↗
PubMed1987

[Ultrasound and CT evaluation of non-lymphomatous splenic focal lesions].

Differential diagnosis problems are caused by the increased, at time occasional, detection of benign and malignant spleen focal lesions in routine superior abdomen ultrasound (US). The following pathologic conditions were reported in 29 patients with focal lesions (excepted systemic diseases): 6 plain cysts, 1 cystic lymphangioma, 3 echinococcus cysts, 3 abscesses, 7 hematomas and 9 metastases. US examination and clinical data together have permitted the differentiation of cysts from solid nodules but has limits in the characterisation of lesions and in the diagnosis of abscesses. Metastases did non present specific US or CT aspects and have been correctly characterized only with aid of anamnestical data and for the coexistence of hepatic lesions. CT has proven superior specificity, compared to US, only in the diagnosis of abscesses and should thus be utilized only in selected cases.

Abscess↗
PubMed1987

[Percutaneous transhepatic cholangioscopy with an 8.5 French endoscopic catheter. Technic and preliminary results].

The authors describe their preliminary personal experience in bile duct endoscopy with a very small diameter catheter (8.5 F) much less traumatic than traditional choledochoscope (15 F). The CE can be reutilized after sterilization; an angiographic guide wire up to 0.042" can be introduced in the operating channel. The CE was used in 3 patients with uncertain cholangiographic diagnosis. Instrument introduction is facilitated when simple technical manoeuvres are followed; there were no difficulties in report interpretation. An experienced interventional radiologist and an endoscopist are needed to handle the instrument. Cytologic sample, biopsy and gallstone lithotomy instruments will increase diagnostic and therapeutic possibilities of the system: for this a wider CE use in the immediate future to complete interventional radiology manoeuvres can be expected.

Bile Duct Diseases↗
PubMed1986

[Clinical evaluation of chemical cholelitholysis using methyl tertiary butyl ether in lithiasis of the bile ducts].

Personal experience is reported in the treatment of calculosis of the biliary ways using MTBE and injected through percutaneous biliary drainage catheters placed surgically or endoscopically in 11 patients in whom surgery appeared to be contraindicated or particularly dangerous. In 10 out of the 11 cases chemical cholelitholysis was successful and the technique is therefore proposed as a valid alternative to surgery in ductal cholelitholysis when sphincterotomy and endoscopic removal of the stones cannot cure the conditions.

Adult↗
PubMed1986

Methyl-TER-butyl ether (MTBE) and endoscopic sphincterotomy. A possible solution for dissolving gallstones.

MTBE was instilled in 6 cases of lithiasis (1 intrahepatic, 5 giant common bile duct stones following EPT). The nasobiliary route (3 cases) and a percutaneous biliary drain (3 cases) were used for this purpose. Complete stone dissolution was achieved in four cases. In the other two, volume reduction was sufficient to allow spontaneous elimination after EPT. A full clinical recovery was obtained in all cases. Further investigation is required in cases of intrahepatic and common bile duct stones when their removal by EPT is not enough to lead to clinical resolution. Follow-up is indispensable.

Aged↗
PubMed1986

[Interventional radiology in non-neoplastic diseases of the biliary tract. A report on 93 personal cases].

Most references in the literature on interventional radiology of the biliary tract refer to the treatment of cancer; only occasionally are benign conditions mentioned. An updated list of useful radiosurgical instruments on the market in Italy is presented. The operating technique from the preparation of the patient to the performance of percutaneous transhepatic cholangiography (PTC), biliary drainage, transhepatic bilioplasty, percutaneous extraction and chemical cholelitholisis of biliary calculi and drainage of biliary collections is then described. A personal series is then presented. It consists of 93 patients in whom one or more of the following conditions were diagnosed: exclusively intrahepatic calculosis (3 cases), calculosis of the common bile duct (23 percutaneous treatments), empyema of the gallbladder (6 cases), suppurating cholangitis (46 cases), sclerotic or inflammatory stenosis (16 cases), biliary collections (14 cases). Results are reported and commented on.

Adult↗
PubMed1986

[Transhepatic percutaneous drainage of the bile with anterior entry in the ducts of the left lobe. Personal experience in 28 cases].

In 28 selected cases (right hepatic lobe lobectomy or atrophy; prevalent dilatation of the left bile ducts; necessary double drainage in the obstruction of the right and left hepatic ducts confluence; etc.) the percutaneous transhepatic cholangiography and the biliary drainage were performed by a left-lobe subxiphoid approach, rather than the currently popular right-lobe approach. By means of this technique some treatments (biliary endoprosthesis insertion, gallstones removal or dissolution, bilioplasty) were executed; these treatments were impossible or very hard to realize by the right-lobe approach. No failures or complications occurred.

Catheterization↗
PubMed1985

Single-dose netilmicin therapy of complicated and uncomplicated lower urinary tract infections in children.

Thirty children (age 3 months to 10 years) with complicated and uncomplicated lower urinary tract infections were treated with a single intramuscular injection of netilmicin 4.5 mg/kg. The diagnosis of lower urinary tract infection was based on the absence of fever and the presence of normal values for erythrocyte sedimentation rate, C-reactive protein concentration and urinary excretion of N-acetyl-beta-D-glucosaminidase. Follow-up urine cultures in all children demonstrated a cure rate of 97% and reinfection and relapse rates each of 7% respectively. The subgroup (12 children) with radiological abnormalities of urinary tract showed a cure rate of 92%, and reinfection and relapse rates of 9% respectively. The rates of cure, reinfection and relapse in the complicated and uncomplicated urinary tract infections were not statistically different (p greater than 0.05). A pharmacokinetic study (performed in 5 children) demonstrated that netilmicin urinary concentrations were over the MIC's of the infecting organisms up to 96 hours after the single-dose injection. Netilmicin was well tolerated and no side effects appeared during treatment. Single-dose netilmicin therapy is an effective and safe regimen for complicated and uncomplicated urinary tract infections in children. The response to single-dose netilmicin therapy seems to be related to its prolonged urinary elimination.

Bacterial Infections↗
PubMed1985

[Percutaneous transhepatic treatment of massive intrahepatic calculosis secondary to stenosis of a biliary-digestive anastomosis].

The authors describe a successful technique for the percutaneous treatment of intrahepatic gallstones from a stenotic Rouxen-Y hepaticojejunostomy. A bilioplasty of the anastomosis with wash-out of the biliary tract has been achieved through two percutaneous external biliary drainage catheters, one inserted in the right biliary ducts and the other placed in the left biliary ducts by means of an anterior approach.

Aged↗
PubMed1985

[Sequential angio-urography (SAU) with photographic image subtraction].

Urography was performed in 250 patients: the technique of bolus injection of a large quantity of contrast medium was used in every case. By means of rapid seriography the early vascular phase was shown and reproduced, when necessary, with image subtraction. The abdominal aorta and the renal arteries were demonstrated in 97.6% of cases. Altogether, in 34.4% of cases the existence of pathological conditions non demonstrable by conventional urography was ascertained; in 12.4% of cases extrarenal pathology was diagnosed. This technique is suggested to be used sistematically, as an alternative to DSA, where digital equipments are not available.

Adolescent↗
PubMed1985

[Validity of the ABAC II system: applicability in the hospital laboratory and verification of breakpoint concentrations in the determination of antibiotic sensitivity].

Two different sensitivity testing methods were evaluated on 183 bacterial strains of Gram-negative clinical isolates in relation to 13 antimicrobial drugs. Comparison between both methods: conventional technique of disk diffusion (Kirby-Bauer) and the automated ABAC breakpoints system, has shown a good agreement of the results (91.1%) according to several investigators. The authors analyze the role of ABAC system and its achievement in routine work of a medium bacteriological hospital laboratory.

Anti-Bacterial Agents↗