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Biomedical subjects

G Gambarini

Publications and source records attributed to G Gambarini.

8 recordsLinked to original sources
PubMed1992

[A clinical study of the efficacy and tolerance of nimesulide compared to flurbiprofen and sodium diclofenac in the prevention and treatment of postoperative pain and inflammatory symptoms in dentistry].

The efficacy and tolerability of a new pharmaceutical formulation of a non-steroid anti-inflammatory drug, nimesulide were studied in a double blind study in comparison with flurbiprofen and diclofenac sodium, in 150 patients suffering from postsurgical pain-inflammatory symptoms. The three drugs, administered in a dose of one suppository twice a day for 10 days, showed marked anti-inflammatory, analgesic and antipyretic activity and produced a significant, progressive improvement in the typical symptoms of the inflammatory state. Nimesulide evidenced the greatest speed and duration of therapeutic action. Assessment on the efficacy and tolerability as expressed separately by the physician and the patients were positive in almost all cases of the three treatments.

Adolescent↗
PubMed1991

[Morphological characteristics of spreaders].

Different kinds of spreaders can be used in the lateral condensation technique. Selection of condensation instruments must not be empirical because the quality of the filling partly depends on the compatibility between the spreader and the prepared root canal. The shape of the instrument should allow for easy insertion to the proper length without any interference. On these bases the Authors evaluated and compared the morphology of some spreaders, and gave data and directions how to rationally use these instruments in clinical practice.

Dental Instruments↗
PubMedDate not supplied

An iron metabolism study in humans by means of stable tracers.

An investigation of iron metabolism in a female patient volunteer by administration of stable iron isotopes as tracers was performed. The applied methodology had already been tested in rabbits in comparison with radioactive tracer technique. The subject under study was given 58Fe solution intravenously and about 45 min later 57Fe solution orally. Ten blood samples were drawn at different times within 522 min from injection. Single iron isotopes content in plasma samples was determined by proton nuclear activation. A Compton suppressor system was utilized to improve the detector limits. The characteristic parameters of iron plasma clearance and of iron intestinal absorption were determined.

Activation Analysis↗
PubMedDate not supplied

Molybdenum metabolism studied by means of stable tracers.

An investigation on molybdenum metabolism by administration of molybdenum stable isotopes was performed. Fractional intestinal absorption was determined in animals by the double tracer technique. The investigated subjects were given an enriched solution of Mo-96 orally and, a few minutes later, an enriched solution of Mo-95 intravenously. Blood samples were drawn at different times following the tracer administration. The Mo-95 and Mo-96 contents in plasma samples were determined by proton nuclear activation. The described methodology offers a means for the study of molybdenum metabolism in humans without radiation risk.

Administration, Oral↗
PubMedDate not supplied

[Obesity and mental disorders in childhood].

The aim of the present study was to establish the prevalence and the type of psychiatric disturbances in a group of 42 obese children (18 boys aged from 6.8 to 13.8 years and 24 girls aged from 2.8 to 15.4 years; weight excess mean +/- 1SD 146.7 +/- 17.4%) and to evaluate the efficacy of a psychological approach of obesity in childhood. The children were in a normal caloric diet and they were encouraged to reach a "target weight" in a given period of time. 22 children were randomly assigned the "analyzed" group (auxological, alimentary and psychological evaluation) and 20 to the "control" group (auxological and alimentary assessment). The psychological evaluation was performed in 20 children (the parents of two children refused to give their consent) by the following tests: creative drawing test; draw a man test (Machover); draw a tree test (Koch); draw a family test (Co-man); Rorschach's test; TAT (Thematic Apperception Test) or, in the younger, the Düss's tales. The results of these psychological tests have been communicated to the patients and or parents. The children were followed for a period of 7 months. We found in 8 children (40%) personality disturbances (which were severe in two cases) and a psychological support was started. The observed main types of disturbances were depression and anxiety. Both were due to a missing harmony between their parents, to a difficult relationship either with their mother or with other children, and to the bad child's opinion of himself. In 4 subjects a psychological support associated with diet promoted a slow, progressive and continuous weight loss.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗