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Biomedical subjects

G Gambardella

Publications and source records attributed to G Gambardella.

At least 37 records · Page 2Linked to original sources

[Early stabilization in severe cervical vertebral and spinal cord injuries].

In the cervical vertebral-myelic trauma a high incidence of bronchopulmonary, metabolic, thromboembolic complications and bedsores is present. The authors, in agreement with the most recent literature (Tator, 1987), affirm that adoption of the precocious stabilization, allowing an equally precocious mobilization, considerably reduces the above-said complications. Thirty patients with vertebral-myelic lesions needing operation for stabilization have been followed. Twenty-one of these, presented irreversible myelic damages and nine cases had partially or completely reversible damages. Only in five cases severe bronchopulmonary affections and bedsores occurred. Thrombo-embolic complications did not occur. The authors conclude that the precocious mobilization allowed by the stabilization realized in acute state, permits a drastic decrease in the complications typical of this kind of affections.

Cervical Vertebrae↗

Computerized use of ICP data. Preliminary elements on the shunt patient.

An incorrect choice of valve may produce a delay in psychomotor development in shunted hydrocephalic children. The intracranial pressure was measured for 24 h in 20 subjects suffering from nontumoral hydrocephalus, obtaining a pressure/volume index with compliance and perfusion pressure data. Their data were entered into a computer and used to determine the correct valve to be chosen.

Cerebrospinal Fluid Shunts↗

[Experimental fetal hydrocephalus. Ventriculo-amniotic shunt].

When the original idea was conceived 8 years ago to develop a surgical technique for the treatment of fetal hydrocephalus, the pathway towards prenatal surgery for this affection was totally unexplored. The operation appeared to be feasible because of the possibility of a ventriculo-amniotic shunt. The most important steps in our experimental studies in the ewe were creation of a fetal hydrocephalus by injection of a suspension of kaolin powder into cisterna magna; the treatment of the hydrocephalus by a mini-ventriculo-amniotic shunt, by cutting the cardiac end of a low pressure Pudenz pediatric catheter. Lambs were delivered by Cesarean two weeks before end of gestation. Coronal sections of brains of control and treated lambs showed reduction in hydrocephalus in the latter. These findings were the basis for the application of the method to treatment of human fetal hydrocephalus.

Amnion↗

A model of the early stages of the human visual system: functional and topological transformations performed in the peripheral visual field.

A model of the early stages of the visual system is presented, with particular reference to the region of the visual field outside the fovea and to the class of retinal and lateral geniculate nucleus cells which are most active in the processing of patter information (X-cells). The main neuroanatomical and neurophysiological properties taken into account are: the linear increase of the receptive fields diameter with eccentricity, the constancy of the overlap factor and the topological transformation operated upon the retinal image by the retino-cortical connection. The type of filtering taking place between the retina and the visual cortex is analyzed and some simulations are presented. It is shown that such a filtering is of a bandpass space variant type, with center frequencies that decrease from the center (i.e. the fovea) toward the periphery of the visual field. This processing is "form invariant" under linear scaling of the input. Moreover, considering the properties of the retino-cortical connection, it is shown that the "cortical images" undergo simple shifts whenever the retinal images are scaled or rotated.

Humans↗