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Biomedical subjects

G G Youngson

Publications and source records attributed to G G Youngson.

At least 19 recordsLinked to original sources

Acute abdominal pain in children: a 25 year comparison.

In the years 1967 and 1992, 649 children were admitted to the Royal Aberdeen Children's Hospital (RACH) as an emergency, with abdominal pain. The aims of this study were to estimate the change in the incidence of appendicitis and patterns of surgical admission between these years. Although the proportion of the childhood population requiring admission showed a small increase over the 25 year period, the pattern of admission changed significantly. While the overall incidence of appendicitis and the number of appendicectomies has fallen, a paradoxical increase is seen in those over 10 years of age. An increase in non-specific abdominal pain was seen which was similar in both sexes. Over the period of study, the risk of proceeding to surgery has fallen by 36%.

Abdominal Pain

Acute pancreatitis in children: a 15-year review.

AIM: To review the aetiology, presentation, diagnosis, management, and sequelae of acute pancreatitis (AP) in children and to assess the relevance of prognostic criteria used to assess severity in adult AP. METHOD: A retrospective review (1978 through 1992) of childhood AP managed in three Scottish paediatric centres. RESULTS: Forty-nine cases of AP (34 male, 15 female) were reviewed (mean age, 7.1 years). The presenting features were abdominal pain and vomiting (80%), abdominal tenderness (73%), and parotid enlargement (22%); back pain was rare (8%). Ultrasound scan (US) findings were abnormal for 24 of 34 patients. Forty-one (82%) were managed conservatively. Six (12%) underwent early laparotomy; three (6%) underwent laparotomy after trauma. Five required subsequent definitive surgery. One patient died. Thirty-five (70%) suffered no sequelae, and five (10%) had further acute pancreatitis. Only half of the eight Imrie prognostic criteria had been recorded in these patients; only three were judged to have severe AP by the criteria. Other "clinically severe" cases were not identified. CONCLUSION: The most common causes of AP were mumps (39%) and trauma (14%); in 12, no cause was identified. US was the most useful imaging tool. The Imrie criteria were of doubtful value but warrant further prospective analysis and possible modification for children.

Acute Disease

Intralobar bronchopulmonary sequestration: antenatal diagnosis.

A child with the antenatal diagnosis of pulmonary cystic adenomatoid malformation underwent thoracotomy and an intralobar bronchopulmonary sequestration was found. Histological examination of the resected specimen showed cystic adenomatoid malformation within the sequestered segment.

Child, Preschool

Haemolytic uraemic syndrome in the defined population of northeast of Scotland.

Twenty seven cases of haemolytic-uraemic syndrome (HUS) were admitted to the Royal Aberdeen Children's Hospital between 1978 and 1989. All cases were from the defined childhood population of the Grampian region of Northeast of Scotland. Thirteen cases were admitted during the 2-year period 1987-1988 (Group 1). Of the 13 cases, 9 (Group 1 a) were admitted within the 11-month period between August 1987 and June 1988, and were from a small area (7 miles radius) within and around the City of Aberdeen. Their mean age was 7.1 years. Twelve cases of HUS were admitted between 1978 and 1986 and 2 cases were admitted in 1989 (total 14 cases; Group 2). Mean age was 3.0 years with no geographical clustering. The average annual incidence for group 2 was 1.25 per 100,000 children 0-16 years old.

Adolescent

Management of the impalpable testis: long-term results of the preperitoneal approach.

During a 12-year period 396 operations for undescended testes were carried out by one surgeon. In 90 boys the testis was impalpable, and exploration was performed using a muscle-splitting preperitoneal approach. Testicular volume and location were prospectively recorded at 3 months and 1 year, 94% were intrascrotal at 1 year and 84% were judged to have grown. At late follow-up 6 to 16 years (mean, 11 years) after ochidopexy, 81% of testes were in the scrotum and 57% were of normal volume. The value and advantages of this operative approach and its place in the management strategy of the impalpable testis are discussed.

Child

Endoscopic restoration of esophageal continuity.

Severe stricture formation after repair of esophageal atresia with tracheoesophageal fistula resulted in obliteration of the esophageal lumen. Patency of the esophagus was restored using endoscopic removal of the scar tissue. The stricture recurrence was subsequently controlled by Collis-Belsey reconstruction of the esophagogastric junction.

Esophageal Atresia

The epidemiology of radial head subluxation ('pulled elbow') in the Aberdeen city area.

The incidence of Radial Head Subluxation in young children in the Aberdeen City Area was ascertained by retrospective review to be 1.2% per year. One hundred and sixty-two cases were recorded, in children aged between 5 and 66 months. The epidemiological features of the condition are reviewed. Extrapolation of these figures to the population of England, Scotland and Wales would suggest an annual incidence of 50,000 cases. This is a condition treatable in general practice, provided of course that the patient is not taken direct to an Accident and Emergency Department.

Child, Preschool

Wound sepsis following Ramstedt pyloromyotomy.

Wound sepsis is common following pyloromyotomy in children and in a retrospective study of 178 cases the incidence of wound infection was 21 (11.8 per cent). On preliminary analysis, three variables were associated with wound sepsis: age, duration of projectile vomiting and surgical technique. Only surgical technique was found to be statistically significant on sequential multivariate analysis. Mass closure with polydioxanone was associated with a 1 per cent (one of 70) wound sepsis rate. Wound sepsis after pyloromyotomy is dependent on technique, and mass closure with polydioxanone is recommended. The routine use of tension sutures should be abandoned.

Female