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Biomedical subjects

G G Snyder

Publications and source records attributed to G G Snyder.

27 records · Page 2Linked to original sources
PubMedDate not supplied

Cryosurgery: theory and application to head and neck neoplasia.

While surgery and radiation therapy remain the time-tested modalities for the treatment of cancer in the head and neck, recent experimental and clinical experience has documented the effectiveness of cryosurgery as an adjunct in the treatment of selected neoplasms in individual patients. A review is provided of the theory of freezing as a method of cell destruction, and experimental and clinical experience illustrate the principles and application of cryosurgery to head and neck tumors.

Cryosurgery↗
PubMedDate not supplied

Malignant fibrous histiocytoma of the larynx.

Fibrous histiocytoma is a rare mesenchymal tumor. The origin is believed to be a pleuri-potential cell, histiocytic in type, which can evolve into a facultative fibroblast under certain conditions. A case of a malignant fibrous histiocytoma in the subglottic larynx is reported. At present, the clinical behavior and degree of malignancy cannot be predicted. It appears that wide, local excision of the tumor with a margin of normal tissue is the treatment of choice. Regional block dissection of lymph nodes is not indicated unless clinically palpable nodes are present.

Adult↗
PubMedDate not supplied

Sebaceous cell carcinoma of the external auditory canal.

Sebaceous cell carcinoma is an extremely uncommon tumor; fewer than 100 cases have been reported, with most of these lesions arising in the meibomian glands in the tarsal plates. Other sites in the head and neck have been noted, but this is the first reported case originating in the external auditory canal.

Adenocarcinoma↗
PubMedDate not supplied

Hamartoma of the larynx: an unusual cause for stridor in an infant.

An extremely rare laryngeal hamartoma causing inspiratory stridor in a 6-week-old infant is reported and the histology discussed. The tumor is benign and responds to simple excision. No other cases have been found in the 20th century American literature.

Hamartoma↗
PubMedDate not supplied

Papillary cystadenoma lymphomatosum of the larynx.

Papillary cystadenoma lymphomatosum, or Warthin's tumor, is a benign lesion of the salivary glands occurring most frequently in the parotid region. Since the initial report of this lesion in 1910, numerous reports have appeared in the literature concerning the occurrence of Warthin's tumor in many extraparotid locations, including the larynx. The vast majority of those tumors arising in the larynx have been disproved because of the absence of one or more of the histologic characteristics of this lesion within the surgical specimen. This paper will review the histologic criteria of Warthin's tumor and the typical clinical occurrence. We will discuss a case of papillary cystadenoma lymphomatosum of the larynx that satisfies all the histologic criteria of this lesion. A review of the possible origins of this tumor will demonstrate that this case may lend support to the hypothesis that papillary cystadenoma lymphomatosum may be the end result of a delayed hypersensitivity reaction.

Adenolymphoma↗
PubMedDate not supplied

Selective section of the recurrent laryngeal nerve for the treatment of spastic dysphonia: an experimental study and preliminary clinical report.

The experimental and clinical results of the surgical treatment of patients with spastic dysphonia by selective section of the adductor branch of the recurrent laryngeal nerve are described. Experimental selective nerve section in dogs appears to retain cordal abduction during inspiration while producing a partial adductor paralysis. Selective section of the recurrent laryngeal nerve has been performed in four patients with 18- to 24-month follow-up. Speech results have been good with maintenance of partial vocal cord motion. No patient has experienced a return of spasticity. We theorize that selective nerve section may decrease the likelihood of the long-term failure that has been seen with complete nerve section by preventing medial fixation of the paralyzed vocal cord.

Animals↗
PubMedDate not supplied

A complication in the use of a Fogarty catheter for foreign body removal during bronchoscopic management.

The Fogarty catheter, developed originally for the removal of intravascular thrombi, has been used in recent years as an aid in bronchoscopic foreign body removal. Complications with the use of a Fogarty catheter are rare. We report the separation of the tip of a Fogarty catheter from the catheter body during rigid bronchoscopic management with resultant lodging of the catheter tip out of bronchoscopic range in the peripheral lower lobe of the lung. Use of a Fogarty catheter during bronchoscopic intervention is discussed as is the availability of different catheter models and their possible problems.

Bronchi↗
PubMedDate not supplied

Immunohistopathology of papillary cystadenoma lymphomatosum (Warthin's tumor).

A retrospective study of various benign salivary gland neoplasms was designed to study the frequency distribution and density of immunoglobulins (Igs) located within their various tissue compartments. Buffered-formalin fixed, paraffin embedded sections of Warthin's tumor, cystadenoma, oncocytoma, autoimmune thyroiditis, normal salivary gland, and reactive peripheral lymph node were obtained and processed via the peroxidase-antiperoxidase method following trypsinization to re-expose antigenic sites. The subepithelial and parafollicular zones of Warthin's tumor show an Ig density distribution (IgA greater than or equal to IgG) much greater than IgM, but the relative densities in the germinal center are (IgG = IgM) much greater than IgA. In contrast, the normal salivary gland displays almost exclusively IgA positive cells with only an occasional IgG or IgM positive cell. In general, the three salivary gland neoplasms considered all display a relatively similar frequency distribution with (IgA greater than or equal to IgG) much greater than IgM and much greater densities of all Igs than encountered in the normal salivary gland; however, the densities of IgA and IgG positive cells are greatest in Warthin's tumor. A similar frequency distribution of immunocytes in the parafollicular zone of autoimmune thyroiditis and Warthin's tumor is noted with an increased density of all Igs occurring in autoimmune thyroiditis. A significant increase in the density of IgA immunocytes is noted in the germinal centers of autoimmune thyroiditis. A comparison of Warthin's tumor with a reactive peripheral lymph node shows a marked increase in the density and frequency of IgA in the parafollicular zone in the former lesion, and significant elevations of IgG and IgM in the latter process both in the parafollicular zone and in the germinal centers. No data generated by this study support an autoimmune etiology of Warthin's tumor. Histopathologically, the oncocytoma appears to represent a pathologic entity distinctly different from papillary cystadenoma lymphomatosum. Our data tend to support the hypothesis that Warthin's tumor arises within ectopic salivary gland elements trapped within paraparotid or intraparotid lymph nodes during embryogenesis. The cystadenoma appears to represent a similar pathologic process arising in salivary gland elements independent of lymphoid tissue.

Adenolymphoma↗