Biomedical subjects
G G Nicholas
Publications and source records attributed to G G Nicholas.
Preservation of venous tissue.
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Long-term results of brachial thrombectomy following cardiac catheterization.
The late results of brachial thrombectomy following cardiac catheterization were evaluated in 20 patients. All patients had a radial pulse present and no symptoms or signs of ischemia of the hand at the time of discharge from the hospital. Late evaluation of these 20 patients revealed 8 in whom the long-term results were classified as failure of the thrombectomy. Four of these had intermittent claudication of the involved arm and hand. None had any tissue loss and four had no symptoms referable to the failed thrombectomy. The one patient who refused surgery had claudication of the affected arm. The mean period of followup was 20.8 months. The rate of failed thrombectomies was twice as high in females than in males. Prolonged time of cardiac catheterization (over 4 hours), delay in diagnosis of more than 24 hours, and omitting the use of systemic heparinization at the time of diagnosis are three factors that appear to increase the likelihood of late failures.
Evaluation of use of the rigid dressing in amputation of the lower extremity.
Twenty-seven arteriosclerotic amputees were evaluated to determine the value of the rigid dressing technique for amputation wound management. Results were compared with those for patients having conventional stump wound management. The two groups were similar in number, age and incidence of diabetes. All the patients treated with the rigid dressing had primary healing of the amputation wound, while 13 patients treated with the conventional dressing had primary healing. Long term rehabilitation to the use of a prosthesis was not improved by the application of a rigid dressing on the amputation wound. Our current preference is use of the rigid dressing applied in the operating room at the time of amputation. If the wound is satisfactory and the general condition of the patient is such that he can use a temporary pylon, it is attached to the cast at the first change, about two weeks after operation.
Protection against the effects of endotoxemia by glucocorticoids.
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Emergency treatment of neck injuries.
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Peritoneal lavage in diagnosis of intraperitoneal injury.
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Early alterations in mitochondrial membrane transport during endotoxemia.
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Traumatic superior messenteric artery-superior messenteric vein fistula.
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Recognizing renovascular hypertension.
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Glucocorticoid protection against endotoxin-induced cellular shock.
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Ruptured abdominal aortic aneurysm.
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Initial management of injury to the neck.
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Reconstructive surgery distal to the popliteal trifurcation. Effect on the history of arterial occlusive disease.
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Diagnosis of diverticulitis of the colon: role of the barium enema in defining pericolic inflammation.
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Shock-induced alterations of mitochondrial membrane transport: effects of endotoxin and lysosomal enzymes on calcium transport.
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Influence of cellular acidosis and altered cation concentrations on shock-induced mitochondrial damage.
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Friction rub in acute cholecystitis: an unusual finding.
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