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Biomedical subjects

G G Marsh

Publications and source records attributed to G G Marsh.

16 recordsLinked to original sources
PubMed1987

Unilateral neglect and constructional apraxia in a right-handed artist with a left posterior lesion.

A rapidly growing tumor in the left posterior parietal lobe of a right-handed, 72 year old artist resulted in bilateral neglect and constructional apraxia that were greater on the right side of his painting than on the left. These changes indicate that a left posterior parietal lesion alters visuospatial perception and constructional ability on both sides of a painting with the contralateral hemispace more impaired than the ipsilateral hemispace. Primitivization of emotional expressions on human faces also occurred.

Aged↗
PubMed1980

Disability and intellectual function in multiple sclerosis patients.

Forty-eight multiple sclerosis patients were rated on the Kurtzke Disability Status Examination and tested on the Wechsler Adult Intelligence Scale. Their disability status scores, ranging from 1 to 9, with a mean of 3.98, correlated significantly only with duration of illness (r = .33, significant at the.05 level). Severity of disability was not significantly correlated with age of patient, age at onset of multiple sclerosis symptoms, Verbal IQ, Performance IQ, or Full Scale IQ. Wechsler Adult Intelligence Scale mean subtest scores ranged from average to bright normal. Scores on Performance subtests with a large motor component were lower than on Verbal subtests measuring verbal overlearned information, abstract reasoning, and vocabulary.

Adolescent↗
PubMed1978

Neuropsychological syndrome in a patient with episodic howling and violent motor behaviour.

A patient with atypical temporal lobe seizures involving violent behavior was found to exhibit the neuropsychological syndrome described by Luria (1966, 1976) as pathognomonic of lesions in the depths of the left temporal lobe. This syndrome, mainly an audioverbal memory defect with relatively intact phonemic hearing, was evident in spite of an intact intellect.

Adult↗
PubMed1973

Does levodopa alter depression and psychopathology in Parkinsonism patients?

Twenty-seven Parkinsonism patients and 31 controls, matched for age and verbal IQ, were tested on an objectively scored personality test (Minnesota Multiphasic Personality Inventory) at the beginning of the patients' levodopa therapy and three months later. Patients, but not the controls, were retested after 15 months of levodopa treatment. The patients, all of whom were intact intellectually, obtained MMPI scores indicating moderate depression before beginning levodopa treatment. There was no test evidence to indicate that levodopa significantly increased or decreased the amount of depression in the patients after three or 15 months of levodopa. The patient group, however, significantly increased their Index of Psychopathology (Ip) score after 15 months of levodopa but not after three months.

Adult↗
PubMed1971

Levodopa's awakening effect on patients with Parkinsonism.

The effects of levodopa on tests measuring auditory and visual perception, auditory, and visual short-term memory, verbal learning, and on attention and concentration were studied in 29 patients with Parkinsonism. Thirty-two control subjects matched with the Parkinsonism patients on age, educational level, and verbal IQ were administered the same tests to control for practice effects. Significant improvement occurred for the Parkinsonism patients in verbal learning (an intermediate memory test) and in auditory perception. These improvements were unrelated to changes in anticholinergic medications, increases in alertness or concentration, lessening of depression, or improved motor ability or control. There was no test evidence of levodopa improving visual perception, short-term auditory or visual memory, alertness or concentration. Thus, there is no objective test evidence for levodopa producing a generalized awakening or an alerting effect in Parkinsonism patients who are intellectually alert and well-orientated. Interpretation of the test findings suggests a specific awakening effect, that of improvement in intermediate memory but not in short-term memory. Overall, the Parkinsonism group scored below the control group on all tests, suggesting that cognitive impairment accompanies Parkinson's disease even in patients who are intellectually intact and well oriented.

Adult↗