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Biomedical subjects

G Frostell

Publications and source records attributed to G Frostell.

At least 55 records · Page 3Linked to original sources
PubMed1975

Variation in pH of plaque after a mouth rinse with a saturated solution of mannitol.

Plaque pH changes were studied in a group of 18 persons after a mouth rinse for 30 seconds with a 50 per cent (w/v) solution of sucrose. One week later the experiment was repeated on the same group of persons, but then with a saturated solution of mannitol instead of sucrose. Dental plaque material was collected from 15 different areas equally distributed among all the teeth. The changes in H-ion concentration in plaque were studied 2, 5, 10, 20, and 30 minutes after the rinse. Saturated mannitol caused an insignificant pH-increase at 2 minutes after which the pH-values remained unchanged. The sucrose (50 per cent) markedly lowered the pH-value, with the lowest value at 5 minutes, after which it slowly rose. The differences were highly significant at all intervals.

Dental Plaque↗
PubMed1975

Degradation of maltose and starch by human saliva and by supernatants of dental plaque material.

The pH-decrease in dental plaque in vivo after mouth rinses with solutions of sucrose and maltose has been compared. No statistically significant differences were found between the results obtained with these two disaccharides. Pooled samples of parotid saliva, centrifuged whole saliva and dental plaque supernatants were separated with the isoelectric focusing technique. The results suggest that maltose is hydrolysed in parotid saliva by the salivary alpha-amylase and in dental plaque by enzymes from sources other than the salivary glands, probably microorganisms. No bacterial alpha-amylases, separated from salivary alpha-amylase, were found in whole saliva specimens or in dental plaque supernatants. Quantitative determinations of "maltase" and amylase activities in parotid saliva, centrifuged whole saliva and dental plaque supernatants from 10 subjects were carried out. The highest enzyme activity of "maltase" was found in the samples of dental plaque and the highest amylase activity in parotid saliva specimens.

Amylases↗