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Biomedical subjects

G Frija

Publications and source records attributed to G Frija.

At least 109 records · Page 6Linked to original sources

[Pericardial effusions (85 cases): radiological aspects (author's transl)].

A radiological study of 85 patients with acute pericarditis and effusion included a group of 35 cases observed before the introduction of ultrasonography and a second group of 50 patients in whom the presence of pericarditis had been confirmed by this investigation. The most important conclusions established were the following: --Absence of radiological signs in 55% of cases (group 1 : 46%, group 2 : 60%); normal heart size in 54% (group 1) and 78% (group 2), and increased size in 34% (group 1) and 20% (group 2). --Hilar manifestations (overlapping and obscuring of the left hilar region) in 26% of cases with a clear predominence of the left forms (14 out of 22). The cardiomegaly was not significant in 28% (group 1) and 14% (group 2). --The high frequency of pericarditis with a normal heart size has to be emphasized. The diagnostic value of hilar manifestations is also mentioned; the sign of left hilar overlapping is described in greater detail. --An overall comparison between the two groups shows, more particularly, the equal importance of left hilar manifestations for the radiological diagnosis of pericarditis. In a general way, it would appear that these hilar signs are the only elements which enable objective diagnosis of pericardial effusions on standard films.

Acute Disease↗

[Radiological signs of primary sarcoma of the kidney in adults : a report on 5 cases (author's transl)].

Primary sarcomas of the kidney are extremely uncommon and the results of their angiographic study are rarely reported. A study of five cases that were confirmed histologically demonstrates the absence of specific clinical and urographic findings. Arteriographic appearances are variable and not related to the histological type. The poorly vascularized forms are traditionally the most frequent (2 out of 5 cases) but are not fundamentally different from adenocarcinomas. The diagnosis can be suspected, however, when there is an infiltrating peripheral tumor extending well beyond the capsule. The hypovascularized pseudocystic forms raise the same arteriographic problems as the adenocarcinomas. Arteriography can diagnose malignancy, but the diagnosis of sarcoma is usually impossible before operation.

Adult↗

[Effort electrocardiography and coronary arteriography following a 1st myocardial infarction. Critical study of the effort test].

Sixty-five patients, convalescent from a first myocardial infarction (anterior in 24 cases; inferior in 41 cases), underwent an effort electrocardiogram on a treadmill and coronary arteriography. In the anterior infarcts, coronary arteriography showed single vessel disease (anterior descending artery) in 54% of cases and double or triple vessel disease in the others. The effort test was positive in only 25% of patients with an anterior infarct. The presence of stenotic lesions of the circumflex artery and/or right coronary artery was unsuspected in 63% of patients. In the inferior infarcts, there was a significant stenosis of the anterior descending artery in 51% of the cases. The effort test was positive in 54% of patients and in 77% of those the anterior descending artery showed a significant stenosis. The appearance (or increase) of ST elevation greater than or equal to 1 mm in the leads facing the infarcted zone was an indication of more severe deterioration in left ventricular function as shown by a more marked reduction in ejection fraction and a more extensive akinetic region. The co-existence of ST elevation in the leads facing the infarcted zone and of ST depression greater than or equal to 1 mm in the reciprocal leads always indicated that another major vessel was involved, but this was only found in 25% of cases in this series.

Angiography↗

[Arteriography in a case of single coronary artery with myocardial ischaemia (author's transl)].

Coronary arteriography is the only examination by which the diagnosis of single coronary artery may be made in vivo by demonstrating the presence of an entire coronary system arising from a common trunk. The discovery may be made under two distinct sets of circumstances: 1 degree Coronary ischaemia in a young subject. Arteriography confirms the diagnosis and the customary 2 degrees Coronary ischaemia in an older individual. Arteriography shows atherosclerotic lesions in a single coronary artery. The severity of the condition is related to the proximal character of the stenoses. The most logical therapeutic approach is aorto-coronary bypass if the quality of the distal network as seen at arteriography makes it possible.

Aged↗

[Multisite cervico-mediastinal venous samples for radioimmunologic determination of parathormone in primary hyperparathyroidism. Results in 24 surgically confirmed cases].

Multisite cervico-mediastinal venous blood samples were collected fort the estimation of parathormone before operation in twenty four patients subsequently confirmed at surgery to have primary hyperparathyroidism. The examination made it possible to lateralise a single (single adenoma: 18 cases) or predominant lesion (multiple adenomas or hyperplasia: 6 cases), in 15 of them (62%). In patients with a single adenoma, exact lateralisation was obtained in 12 out of 18 cases (9 had selective samples with 7 accurate lateralisations). This lengthy and costly examination is essentially of value in localisation and should be used essentially in patients with virtually definite primary hyperparathyroidism and in whom the responsible lesion has not been discovered at exploratory operation.

Blood Specimen Collection↗

Value and limits of arthrography in the study of pathological mediopatellar plicae of the knee; a comparison with arthroscopy.

The results from arthroscopy and arthrography were compared in a prospective study of the mediopatellar plicae in 100 knees with internal disorders. With reference to arthroscopy, the sensitivity and specificity of arthrography for the detection of mediopatellar plicae were, respectively, 83.6 and 88.8%. The arthrographic signs of pathological plicae were: a thick plica, thicker than the internal condylar cartilage (sensitivity: 72%; specificity: 84%) and an interposed plica (sensitivity: 85%; specificity: 81.8%). Statistically the arthrographic signs agreed with the arthroscopic signs. The two methods did not differ significantly in their contribution to the diagnosis of pathological plicae.

Adolescent↗

Quantitative assessment of average velocity in inferior vena cava by phase-display MR imaging: pulsed Doppler correlation.

A technique for measuring average velocity in the inferior vena cava (IVC) by using phase-display magnetic resonance (MR) imaging is described. Fifteen healthy subjects were imaged, and the velocities and spectra obtained by MR were compared with pulsed Doppler results. Distortions of the "zebra-striped" images obtained along the axis of the vessel were measured at the same level of the IVC as in pulsed Doppler. Measurements of average velocities in the IVC made by the two methods were very similar, and velocity curves obtained during the cardiac cycle were superimposable. Phase-display MR imaging has the potential to noninvasively assess blood flow in large vessels as accurately as pulsed Doppler.

Adult↗

A study of coronary artery bypass graft patency using MR imaging.

This is a prospective study comparing selective angiography and magnetic resonance (MR) imaging in the evaluation of the patency of coronary artery bypass grafts (CABGs). Twenty-eight patients with 52 grafts were studied (10 internal mammary artery grafts, 19 saphenous vein grafts including 2 sequential grafts, and 15 right coronary artery saphenous vein grafts). The mean interval between MR imaging and the surgical procedure was 13.2 months. Results obtained with angiography were as follows: 39 patent grafts; 4 patent but stenotic (greater than 50%); 9 occluded CABGs. Magnetic resonance imaging was performed with axial imaging, spin echo images, and electrocardiographic gating. Grafts that were normal on angiographic examination appeared without a signal on both the first and the second echoes in 38 of 39 cases. Grafts that were patent but presented significant stenosis as evidenced by angiography presented the same appearance. In one case, there was an aspect corresponding to a decreased blood flow (presence of a signal on the first echo that became stronger on the second echo). The CABG occlusion was determined in seven of nine cases. Occluded grafts twice presented a signal variation corresponding to an old thrombus formation. In two cases, only the origin of the graft was visible without any visualization of its distal portion. In three other cases, neither the proximal nor the distal portions of the graft were identified. Among six CABGs that could not be identified, three were patent. This study demonstrated that MR imaging makes it possible to correctly identify patent CABGs, but this modality has significant limitations because patent but stenotic CABGs may present in the same way as patent CABGs without stenosis. On the other hand, the correct identification of occluded grafts may be accurately performed using MR imaging.

Coronary Angiography↗

Estimation of gas and tissue lung volumes by MRI: functional approach of lung imaging.

PURPOSE: The purpose of this work was to assess the accuracy of MRI for the determination of lung gas and tissue volumes. METHOD: Fifteen healthy subjects underwent MRI of the thorax and pulmonary function tests [vital capacity (VC) and total lung capacity (TLC)] in the supine position. MR examinations were performed at inspiration and expiration. Lung volumes were measured by a previously validated technique on phantoms. Both individual and total lung volumes and capacities were calculated. MRI total vital capacity (VC(MRI)) was compared with spirometric vital capacity (VC(SP)). Capacities were correlated to lung volumes. Tissue volume (V(T)) was estimated as the difference between the total lung volume at full inspiration and the TLC. RESULTS: No significant difference was seen between VC(MRI) and VC(SP). Individual capacities were well correlated (r = 0.9) to static volume at full inspiration. The V(T) was estimated to be 836+/-393 ml. CONCLUSION: This preliminary study demonstrates that MRI can accurately estimate lung gas and tissue volumes. The proposed approach appears well suited for functional imaging of the lung.

Adult↗

Transcatheter embolization of multiple pulmonary artery aneurysms in Behçet's syndrome. Report of a case.

Transcatheter embolization of a pulmonary artery aneurysm in Behçet's disease has rarely been attempted. A report is presented of a case with four pulmonary aneurysms and massive hemoptysis. Transcatheter embolization was successfully performed in three of these aneurysms, with clinical improvement during a follow-up period of 11 months. Technical problems, hazards, and indications for embolization in these patients are discussed.

Adult↗

Normal laryngeal CT findings after supracricoid partial laryngectomy.

BACKGROUND AND PURPOSE: Supracricoid horizontal partial laryngectomy (SCPL) is increasingly used to treat endolaryngeal carcinoma. However, few radiologic reports of these procedures exist. Our purpose was to evaluate the normal CT appearance of the neolarynx after surgery. METHODS: SCPL includes cricohyoidopexy (CHP), cricohyoidoepiglottopexy (CHEP), and tracheocricohyoidoepiglottopexy (TCHEP). We examined CT scans obtained from 18 patients without local superficial recurrence who underwent SCPL: 10, CHEP; seven, CHP; and one, TCHEP. Three reference sections were used to analyze the main surgical reconstruction: an upper section through the hyoid bone, a lower section through the cricoid cartilage, and a middle section in between. The distance between the hyoid bone and cricoid cartilage was measured. RESULTS: The epiglottis and valleculae were visible in the upper section in seven of 10 patients who underwent CHEP; this finding allowed distinction between CHEP and CHP. The arytenoids were depicted in 13 of 18 cases and reflected neolaryngeal shortening. The lower section showed the empty cricoid lumen lined by a thin mucosa; the anterior arch of the cricoid was amputated at TCHEP. The middle section showed the neovestibule, the lateral boundaries of which were the hypertrophic neoaryepiglottic folds; the anterior limit was the epiglottis for CHEP or the base of the tongue for CHP. The average distance between the hyoid bone and cricoid cartilage was 11 mm. CONCLUSION: Normal CT anatomy of the larynx after SCPL is defined. Three key sections may accurately distinguish the various types of SCPL. CT is a valuable tool for depicting tumor recurrence, especially when the tumor is submucosal.

Aged↗

MR imaging of acute spinal cord injury: results of an experimental study in dogs.

A weight-drop model was used to induce 16 acute lesions of varying severity in the spinal cords of eight mongrel dogs. The subsequent 3- to 7-hr postinjury MR images (0.5 T) were assessed. T1-weighted images contributed little information. Injection of gadolinium tetra-azacyclododecane tetraacetic acid did not result in significant enhancement. T2-weighted sequences offered precise detection and delineation of the lesions, displaying fusiform hyperintense signal abnormalities that corresponded to both edema and hemorrhage. In low-impact injuries, abnormalities were small and centrally located, sparing the periphery of the spinal cord. In these cases hemorrhage was minimal and limited to the center of the lesion. In severe-impact injuries, MR showed widespread longitudinal extension with involvement of the periphery of the spinal cord. In the most severe injuries, a central heterogeneous signal component was frequently observed opposite the site of impact because of important hemorrhage within the cord. Overall, hyperintense areas correlated closely with lesion severity, as demonstrated by pathologic findings. T2-weighted MR images obtained at 0.5 T were found to be reliable in the evaluation of acute spinal cord trauma.

Animals↗

[Varices of the anterior mediastinum in a case of portal hypertension treated by omentopexy (author's transl)].

The authors report a case of portal hypertension due to cirrhosis of unknown aetiology, treated by omentopexy. They note the existence of a large varice of the anterior mediastinum responsible for the formation of two opacities of the left cardiophrenic angle. They discuss the nature and formation of these appearances in relation to the omentopexy and the portal hypertension.

Female↗