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Biomedical subjects

G Fries

Publications and source records attributed to G Fries.

At least 55 records · Page 3Linked to original sources

[Perspectives of pedagogic approaches to rehabilitation in the psychosocial care of the elderly].

Rehabilitative pedagogics deal with the entirety of "educational", or "pedagogical", approaches and activities that seek to diminish the physical, mental and/or psychosocial handicaps faced by disabled people, or to develop alternatives enabling them to compensate for existing disabilities Specific difficulties are present in the care and treatment of older persons, which--despite a lack of empirical substantiation--have entailed a widespread assumption that there is only very limited benefit in rehabilitating older people. This view is critically discussed, and perspectives for "worthwhile" rehabilitative-educational approaches in the psychosocial and psychosomatic care of elderly people are presented.

Aged↗

Health implications of 2,3,7,8-tetrachlorodibenzodioxin (TCDD) contamination of residential soil.

Extrapolations from animal toxicity experiments (including carcinogenicity and reproductive effects) to possible human heath effects can be used to estimate a reasonable level of risk for 2,3,7,8-tetrachlorodibenzodioxin (2,3,7,8-TCDD). Extrapolations are derived from: (1) review of published studies, (2) a complex set of assumptions related to human exposure to contaminated soil, and (3) estimates of (a) a dose response curve, (b) appropriate margins of safety, and/or (c) applicable mechanisms of action. One ppb of 2,3,7,8-TCDD in soil is a reasonable level at which to begin consideration of action to limit human exposure for contaminated soil.

Animals↗

[Treatment of gonarthrosis].

In an open study in 89 out-patients the effect of superoxide dismutase (Orgotein) in gonarthrosis (n = 75), post-operative or post-traumatic irritation (n = 8) and chondropathy (n = 6) was investigated. Orgotein (4 mg) was give intra-articularly once weekly for several weeks. The overall rating showed efficacy of this new antiphlogistic compound in 81 out of 89 patients (91%). In eight patients the results of treatment were insufficient. In 65 (80%) out of the 81 successfully treated patients no relapse appeared. Six patients reported reappearance of slight complaints so that in 75 out of 81 successfully treated patients, even after repeated controls, a long lasting pain relief could be achieved. Only in three cases the tolerance of Orgotein was not assessed as "very good" ("good" in one case and "moderate" in two cases). The patients reacted--despite good tolerance of the first injections--after the 4th or 5th injections with irritation and swelling as well as effusion; these symptoms were reversible within 24 hours.

Adult↗

Herd health status of animals exposed to polybrominated biphenyls (PBB).

The health status of 16 herds of dairly cattle exposed to low levels of polybrominated bipenyl (PBB) was compared with that of 15 control herds. Milk production of the contaminated herds was not significantly changed in 1972, 1973, and 1974 and was not significantly different from that of control herds in the same years. Mortality of adult cows and calves, the percentages of cows culled from the herds because of old age and low production, disease, or sterility, and the general health conditions were similar in the two groups. Serum concentrations of calcium, glucose, and cholesterol in contaminated herds were significantly different from those of the control herds, but the relationship to PBB exposure needs further investigation.

Animal Feed↗

[The effect of prindolol on the blood-pressure profile of hypertensives (with special consideration of response to exercise and plasma-renin activity) (author's transl)].

Using microcatheter blood pressure telemetry, the pressure-lowering effect of prindolol (Visken), a beta-blocking drug, was tested at a dose of 10 mg three time daily by mouth in eight patients with essential hypertension (WHO stage II) and low to normal plasma-renin activities. After about ten days of treatment, the hypertensive reaction to everyday physical exercise (walking, climbing stairs, bicycle ergometry) was especially favourably affected. The average blood-pressure reduction at rest was 18.6/12.1 (systolic/diastolic), on stair climbing 41.5/17.2 mm Hg.

Adult↗