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Biomedical subjects

G Freni

Publications and source records attributed to G Freni.

18 recordsLinked to original sources

Integrated urban water modelling with uncertainty analysis.

In the last twenty years, the scientific world has paid particular care towards the problems that involve the environment. Accordingly, several researches were developed to describe phenomena that take place during both wet and dry periods and to increase the knowledge in this field. In particular, attention was addressed towards the problems linked with receiving water body pollution because of the impact of rain water in the urban environment. In order to obtain a good description of the problem, it is important to analyse both quantity and quality aspects connected with all the transformation phases that characterise the urban water cycle. Today, according to this point, integrated modelling approach is spreading, aiming to find solutions to improve the quality characteristics of the receiving water body. Because several models are connected together for analysing the fate of pollutants from the sources on the urban catchment to the final recipient, classical problems connected with the selection and calibration of parameters are amplified by the complexity of the modelling approach increasing the uncertainty and reducing the reliability connected with a model's application. For this reason, a parsimonious integrated modelling approach has been developed and its uncertainty has been evaluated adopting the well known GLUE framework. For the purpose of the study, the uncertainty analysis has been applied to a "semi-hypothetic" case study obtained connecting Fossolo catchment (Bologna-Italy) to the Oreto river near Palermo (Italy).

Cities↗

Feeding troubles following delayed primary repair of esophageal atresia.

Severe feeding troubles were recorded in five babies with long-gap esophageal atresia who underwent, between 1985 and 1990, a delayed primary anastomosis after spontaneous growth of their esophageal stumps. A comparison with 20 cases of direct esophageal anastomosis, operated on in the same period, was carried out by means of recorded esophagrams, pH monitoring and questionnaires charting the growth pattern and feeding habits of the patients. Bottle feeding, and, later on, the introduction of semi-solid foods was significantly retarded in the group of children with delayed primary anastomosis (labeled as group B) as well as height and weight parameters. Failure to complete feeds, dysphagia, vomiting, coughing, choking and recurrent respiratory symptoms were also significantly more common in this group than in the primary anastomosis group (labeled as group A) even in the absence of stricture. Variable degrees of disordered esophageal motility were present in all patients but pooling of the contrast medium, retrograde flow and delayed clearing of the esophagus were more frequent in group B. No patient was shown to have associated hiatal hernia. A 24 hour pH recording showed severe gastroesophageal reflux in 4 out of 13 cases of group A and in 3 out of 5 cases of group B. Clearing times were significantly delayed in all refluxing children. Our data suggest that the retarded start of oral feeding and swallowing coordination in patients with delayed primary anastomosis add further negative factors to their congenitally impaired esophageal motility, causing protracted dysphagia which represents a major problem for both family and hospital staff.

Anastomosis, Surgical↗

[Unusual case of ano-rectal malformation].

The authors present an unusual case of anorectal malformation: it's an intermediate from with a cutaneous fistulous tract. This case is similar to that described in 1982 by the Japan study group of anorectal anomalies.

Anus, Imperforate↗

[Ectopic bronchogenic cyst].

The authors report a case of ectopic bronchogenic cyst. They review the literature and don't find any other similar case. This case is well explained by the embryology.

Bronchogenic Cyst↗

[Omphalocele: 10-year-experience].

We review our experience of 32 cases of omphalocele treated in the last ten years. Improved neonatal intensive care unit, as well as other support care measures, allowed to extend even to the large defects the indication to radical primary repair. Our experience has supported that this is the method of choice in almost all cases. At present the surgical success depend on associated anomalies, cardiac especially (25% in our series), and on development of sepsis. Analysis of the results shows an overall mortality rate of 41% in the period 1973/1982, significantly decreased to 33% in the last five years.

Administration, Topical↗

[Ingestion of caustics in childhood: proposal for a therapeutic protocol].

Caustic ingestion is a traumatic event not rare in the infancy. The authors, after a brief discussion of their cases and after a revision of the literature, propose a therapeutic protocol for the treatment of caustic ingestion in the infancy. This protocol is based on the esophagoscopy in the first day and on the antibiotic and corticotherapy in the first two weeks. When there is an esophageal stenosis, the authors propose weekly esophageal dilatations.

Anti-Bacterial Agents↗