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Biomedical subjects

G Franco

Publications and source records attributed to G Franco.

At least 109 records · Page 6Linked to original sources
PubMed1983

[Proposal for evaluating the psychological effects of exposure to non-ionizing radiation in the work environment].

Because of the growing national and international spreading of devices producing non-ionizing radiations, the AA consider the possibility of a deep study on some of the most precious and interesting effects, though controversial at the same time, described in occupationally exposed subjects: the psychological ones. Such a study, however, presents considerable difficulties because of the great deal of personal, domestic and social factors responsible for the arising of such a symptomatology. Therefore the AA suggest the use of a set of tests particularly aiming at leaving out such factors in the genesis of the psychological troubles; this set must be previously administered to a carefully selected sample in order to verify its accuracy, reliability, sensitivity and specificity, so that it will be possible to extend afterwards the research to larger samples of population.

Adult↗
PubMed1982

Assessment of coronary heart disease risk among viscose rayon workers exposed to carbon disulfide at concentrations of about 30 mg/m3.

Total cholesterol, high-density lipoprotein cholesterol, triglycerides, blood pressure, and two coronary heart disease risk indices were assessed for a group of 70 male viscose rayon workers exposed to carbon disulfide (CS2) and individually matched for age, height, and weight with 70 male referents. Environmental CS2 levels were below 35 mg/m3 during 1972-1979. The study, undertaken to define some risk factors for coronary heart disease and to determine some parameters of lipid metabolism, found no differences between the group of CS2-exposed workers and the referents. Apart from a possible toxic effect directly induced by CS2 on the myocardium, the results suggest that CS2 exposure up to about 30 mg/m3 does not promote coronary atherosclerosis and hence does not increase coronary heart disease by this mechanism.

Adolescent↗
PubMed1980

[Diagnosis value of Doppler signal. From the finger pulp (author's transl)].

Receiving of Doppler signal from the pad is able to make complete the diagnosis of vascular acrosyndromes beside clinics, functional processes and above all capillaroscopy at the fingertip, conjunctiva and skin surface. There is not any signal in acrocyanosis, generalized sclerodermia, sharp's disease and chronical arteriopathy. There is a signal in P.A.N., dermatomyositis and L.E.D., likewise in primary form of Raynaud, in acroparestesias, in erythralgias... On the other and, in case of acrocyanosis mixed with Raynaud, the signal vanishes.

Adult↗
PubMed1979

[New therapeutic prospects in lead poisoning: alpha-mercaptopropionylglycine].

The action of alpha-mercaptopropionylglycine has been studied in 27 subjects occupationally exposed to lead. In addition to improved efficiency of liver function, the results show a tendency to normalization of the various porphyrinic metabolism parameters considered. A significant increase was observed in erythrocyte dehydratase ALA activity together with an equally significant diminution in urinary excretion of delta-aminoleuvlinic acid. Urinary coprorphyrin and erythrocyte protoporphyrin IX values were also down. The tendency of metabolic changes to normalize as a result of the toxic action of lead suggests the use of alpha-mercaptopropionylglycine in the treatment of lead poisoning.

Adult↗
PubMed1977

[Calculation of the systolic time as an index of thyroid performance].

Two methods for determining some features of cardiovascular behaviour in dysthyroidism are compared: time of appearance of the femoral sphygmic wave (as an expression of the cardiovascular response to thyroid hormones); systolic times, particularly tension time (as an expression of the contractile function of the myocardium only). Results in 52 euthyroid, hyperthyroid and hypothyroid subjects showed that systolic times (especially tension time) are more accurate and more discriminating in the assessment of thyroid performance. Measurement of this interval is thus proposed as an index for the appraisal of myocardial contractility in dysthyroidism, and as an additional means of evaluating thyroid performance.

Adolescent↗
PubMed1976

[Achilles reflexogram and hemodynamic parameters in the evaluation of thyroid function].

Among the numerous techniques designed to explore thyroid function, two which examine important peripheral aspects are considered: Achilles osteotendinous reflectivity (determination of contraction time and relaxation time of the gastrocnemius muscle) and the response of the cardiovascular system to thyroid hormones (determination of the time of onset of Korotkoff's sound and that of the brachial sphygmic wave). Comparison of the results obtained with these two techniques in a group of 60 euthyroid subjects, 17 hypothyroid and 25 hyperthyroid cases, shows that the techniques are comparable as regards precision, reproducibility, and sensitivity and are of indubitable importance for the assessment of thyroid function through the study of two of its peripheral aspects.

Achilles Tendon↗
PubMed1976

Systolic time intervals as a measure of left ventricular function in viscose rayon workers exposed to carbon disulfide.

In a group of viscose rayon workers exposed to carbon disulfide the systolic time intervals were calculated. They were determined from the simultaneous recording of an ECG, a phonocardiogram, and arterial pulse tracings. Results indicate a shortened left ventricular ejection time (lvet) and a prolonged isovolumetric contraction time (ICT), together with an increase in the ratio of ICT to LVET. These alterations, which occurred in the absence of any clinical signs or symptoms of heart disease, are interpreted as a consequence of an impaired left ventricular contractility, comparable to mild coronary dysfunction. Literature data support the hypothesis that the biochemical mechanisms involved in the effect of carbon disulfide on myocardial cells are (a) an interference with energy metabolism from the inadequate availability of thiamine and nicotinamide or a direct inhibition of cytochrome or (b) an interference with catecholamine metabolism and defective hormonal control of the energy utilization process. Impaired left ventricular function in rayon viscose workers exposed to carbon disulfide represents an early and highly sensitive sign of carbon disulfide intoxication, and the use of systolic time intervals as a noninvasive measure of myocardial performance may be a useful method for monitoring carbon disulfide exposed people.

Air Pollutants↗