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Biomedical subjects

G Ferrey

Publications and source records attributed to G Ferrey.

At least 19 recordsLinked to original sources
PubMed1992

Antigen specificity and cross-reactivity of fifteen monoclonal antibodies against porcine pancreatic alpha-amylase II and its AB and C domains.

Highly productive hybridoma secreting mabs specific for porcine alpha-pancreatic amylase II were established. Fifteen clones were selected. The mabs produced (KD = 1.68-11.2 nM) were checked for cross-reactivity with six heterologous antigens, namely porcine pancreatic alpha-amylase I, barley amylase, human pancreatic alpha-amylase, Taka amylase and triose phosphate isomerase, using direct ELISA assay; mabs were classified within seven groups: in a few groups mabs cross-reacted with a single heterologous antigen either porcine pancreatic amylase I (6 mabs) or barley amylase (2 mabs) or human pancreatic amylase (3 mabs). Two other groups cross-reacted with two heterologous antigen either porcine I and human or porcine I and barley. Only one mab out of fifteen cross-reacted in direct ELISA binding to all amylases and triose phosphate isomerase. Using sandwich ELISA test only three mabs were found to bind porcine amylase II present at high concentration. Results consistent with direct porcine amylase binding were obtained from binding inhibition assays. Analysis by the additivity test allowed to find that 3 mabs, B10.10, B1.11, C6.4 recognize distinct epitopes while the epitopes for the other pairs tested are either overlapping or at least close to each other. Finally mabs binding specifically either to the AB or to the C domain fragment or to both fragments have been obtained.

Animals↗
PubMed1990

[Glossodynia].

Glossodynias are a build up of painful lingual syndromes with neither a detectable visible lesion, nor of a known organic origin. An obvious discordance between the subjective feelings and the weakness, even absence of an objective lesion support able to explain them, can be observed. Being often considered by physicians to be of a psychological origin, they are always the object of never-ending research for a detectable lesion which would explain their complications. Following consultations with 114 patients in the department of Stomatology, and in collaboration with our neuropsychiatrist colleagues in the same hospital, we took stock of this frequent application which bothers the buccal specialist, who does not know to consider it or how to treat it.

Diagnosis, Differential↗
PubMed1983

[Voluntary and reflex oblique ocular movements in cranial injuries].

In a population of 241 head injuries, some of which dated prior to 3 months and others after, the modalities of graphic responses to an oblique stimulation are described (optokinetic test and ocular calibration). In fact, the distribution of the various types of graphic responses differ statistically depending on the age of the injury. In injuries less than 3 months old a majority of oblique ocular responses were found to be of the intermediate type, while in those with injuries of more than 3 months ago, the oblique ocular responses of a rotary type predominated. However, above all the results of the video recording used to visualize the ocular responses, which until now have been presented graphically, will be discussed.

Adolescent↗
PubMed1977

A psychometric stury of 34 patients afflicted with spasmodic torticollis.

The clinical and psychometric comparison of two group of patients, one with spasmodic torticollis, the other with operated herniated disc, showed closely related psychological profiles. The most important perturbations are found in spasmodic torticollis and seem related to the disease's chronicity. In no case was a predominant hysteric structure found. The results of these investigations on the disorder's etiology are discussed.

Adult↗
PubMed1975

[Anxiety-trait, anxiety-state, real change, apparent change].

After reviewing the different techniques assessing state-axniety, the authors emphasize the difficulties to distinguish state from trait on the sole basis of factorial content. Results obtained on different samples (mental patients, surgical patients and normal subjects)through two new anxiety self-rating scales (trait and state) are presented. On the basis of these results, the authors show the usefulness of the score indicating the discrepancy between trait and state levels. It appear that the direction (positive or negative) of the difference between trait and state levels gives a better evaluation of the actual state than the state score alone. The results imply the utilization of both self-rating scales (trait and state) in order to obtain the optimal assessment of the state.

Anxiety↗