Search PubMed⌕ Search

Biomedical subjects

G Familiari

Publications and source records attributed to G Familiari.

69 records · Page 4Linked to original sources
PubMed1979

Ultrastructural characteristics of idiopathic spermatidic arrest.

Previous studies on some cases of idiopathic spermatidic arrest showed an anomaly in glucose metabolism, in particular decreased utilization of glycogen at stage 3 of spermatogenesis, when condensation of the spermatid head commences. Histological patterns seen on light microscopy confirmed the reduced utilization of glycogen at stage 3 of spermatogenesis. Electron microscopy revealed an arrest at stage 3 of spermiogenesis and, at the cytoplasm level of the Sertoli cell, a modification in the smooth endoplasmic reticulum characterized by the presence of dilated cisternae. From a morphological viewpoint, the equivalent of a biochemical modification which characterizes this maturation disorder in the germinal epithelium is hypothesized.

Humans↗
PubMed1978

Surface coat in steroid-secreting cells of the mouse ovary.

Steroid-secreting cells (luteal, thecal and interstitial cells) of the mouse ovary have been studied with the ruthenium red method to stain the "cell coat". The results showed that a typical cell coat covers the entire surface of the plasma membrane except where the cells are connected by specific cell junctions. Further, particularly heavy concentration of ruthenium-red-reacting material was demonstrated in pericapillary and intercellular spaces. The differences in the thickness of the cell coat and its topographical modifications among different groups of steroidogenic cells may be related not only to intercellular adhesion and interactions but also concerned with a function of control in which the cell permeability is modified in relation with phenomena of cell recognition.

Animals↗
PubMed1977

Myosin-like microfilaments in the human normal and pathological testis.

The immunofluorescent staining of the human normal testis shows that both peritubular and tubular cells bind antimyosin-like antibodies. The same cells are provided with a large amount of microfilaments within the cytoplasm. The thin microfilaments observed by electron microscopy in various cells of the human testis likely correspond to the sites of immunofluorescent staining. In pathological specimens there can be observed a decrease in peritubular smooth muscle cells associated with a decrease in cytoplasmic microfilaments and in the immunofluorescent staining of some cells.

Cytoplasm↗
PubMed1977

The contractile nature of the tubular-like cells of the parietal layer of the Bowman's capsule in male mice. An immunochemical and ultrastructural study.

The tubule-like cells (TLC) of the parietal layer of the Bowman's capsule of the renal corpuscle in normal male mice are provided with bundles of thin microfilaments (50-70 A). Moreover, the ultrastructural observations demonstrated that similar thin filaments (50-70 A) are located in the flattened cells of the parietal layer of the Bowman's capsule and in the tubular cells. All the above cells bind antimyosin-like antibodies. Considering the correspondence between the immunochemical and ultrastructural findings, it is suggested that the microfilaments located in TLC contain a 'myosin-like' protein.

Animals↗
PubMed1975

Contractile microfilaments in granulosa cells. An ultrastructural and immunochemical study.

Electron microscope observations demonstrated bundles of microfilaments measuring 40-70 A in diameter in the granulosa cells of normal developing follicles of rabbit ovary. The microfilaments appeared concentrated in the cortical areas of the cytoplasm and within large evaginations and microvilli. In addition the filaments were particularly abundant in the granulosa cells of corona radiata and free cells in the cavity. Immunofluorescent staining on frozen sections of rabbit ovary demonstrated that the granulosa cells of developing follicles bind antimyosin-like antibodies (AMA). Considering the correspondence between the immunochemical and ultrastructural fingings it is suggested that the microfilaments contain a "myosin-like" protein. It seems then reasonable to suggest that the ovarian follicles are not kinetically passive organs, but they contain contractile filaments for their specific functions.

Animals↗
PubMed1975

Microfilaments in granulosa cells of rabbit ovary: immunological and ultrastructural observations.

The present observations demonstrated that the granulosa cells of developing follicles in the rabbit ovary bind antimyosin-like antibodies (AMA). The same granulosa cells studied with the electron microscope showed bundles of microfilaments in the cortical areas of the cytoplasm and within microvilli and large cellular evaginations. The immunochemical and ultrastructural results suggest that the ovarian follicles are not passive organs, but, containing contractile granulosa cells, are capable of producing "in vivo" discrete movements.

Animals↗
PubMedDate not supplied

Gastric re-resection in emergency.

BACKGROUND/AIMS: We reviewed a consecutive series of patients with acute complications following gastric resection, in order to evaluate the role of gastric re-resection as the operation of choice in emergency. METHODOLOGY: Records of 90 patients with acute complications following gastric resection observed from January 1991 to January 1996 were retrospectively analyzed. RESULTS: Hemorrhagic events occurred in the vast majority of cases (87), either as acute complications after a long time since surgery (78 cases) or as early postoperative complications (9). Among late acute complications, three cases were related to bleeding cancer of the gastric stump. Anastomotic obstructions presenting as acute complications occurred in 3 cases. Emergency surgery was indicated in three cases of acute obstruction, in 1 case of bleeding cancer of the gastric stump, in 9 (12%) out of the 75 remaining late acute hemorrhagic complications and in 1 (11%) out of 9 early hemorrhagic complications. Completion gastrectomy was chosen in the one case of bleeding cancer of the gastric stump with indication for emergency surgery. Gastric re-resection was performed in 11 cases: 9 for hemorrhagic complications and 2 for obstructive acute complications. In two cases, one for hemorrhage and one for occlusion, other surgical procedures were carried out. CONCLUSIONS: Gastric re-resection can represent the most suitable operation in acute complications following gastric resection.

Adult↗