Progressive linear lichen planus and metastatic carcinoma.
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Biomedical subjects
Publications and source records attributed to G F Sciallis.
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A case of angiolymphoid hyperplasia presenting as a pilar cyst is presented herein. The clinical appearance of the lesion is described and its relationship to the blood vessel in which it grew is noted. Previous reports have shown neither the appearance of such a solitary lesion nor its intravascular growth. A review of the literature is also presented.
We evaluated, dermatologically and ophthalmologically, 26 patients who had chronic blepharitis (meibomitis); we also investigated 26 age- and sex-matched controls. All of the blepharitic patients had an abnormality of sebaceous gland function ranging from seborrhea sicca to seborrheic dermatitis or acne rosacea, suggesting a generalized sebaceous gland dysfunction that included the meibomian glands. Sebaceous gland abnormalities most frequently involved the cool areas of the face or scalp. Stagnation of the meibomian glands presumably caused a defect in the tear lipid layer; this resulted in an unstable tear film that produced superficial punctate keratopathy. The break-up time was much lower in these patients than in controls. The break-up time returned to normal or super-normal levels when fresh meibomian secretions were expressed into the tear film. The superficial punctate keratopathy had the characteristics of those seen in conditions with a known unstable tear film and not of those experimentally produced by staphylococcus toxin.
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