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Biomedical subjects

G F Harris

Publications and source records attributed to G F Harris.

At least 19 recordsLinked to original sources

Walker-assisted gait in rehabilitation: a study of biomechanics and instrumentation.

While walkers are commonly prescribed to improve patient stability and ambulatory ability, quantitative study of the biomechanical and functional requirements for effective walker use is limited. To date no one has addressed the changes in upper extremity kinetics that occur with the use of a standard walker, which was the objective of this study. A strain gauge-based walker instrumentation system was developed for the six degree-of-freedom measurement of resultant subject hand loads. The walker dynamometer was integrated with an upper extremity biomechanical model. Preliminary system data were collected for seven healthy, right-handed young adults following informed consent. Bilateral upper extremity kinematic data were acquired with a six camera Vicon motion analysis system using a Micro-VAX workstation. Internal joint moments at the wrist, elbow, and shoulder were determined in the three clinical planes using the inverse dynamics method. The walker dynamometer system allowed characterization of upper extremity loading demands. Significantly differing upper extremity loading patterns were identified for three walker usage methods. Complete description of upper extremity kinetics and kinematics during walker-assisted gait may provide insight into walker design parameters and rehabilitative strategies.

Adult↗

Surgical rehabilitation of the planovalgus foot in cerebral palsy.

The objectives of this study were to quantitatively determine the effects of subtalar arthrodesis on the planovalgus foot using three-dimensional (3-D) gait analysis and plantar pressure measurements. Twelve children and adolescents with planovalgus foot deformity secondary to spastic cerebral palsy participated in this outcome study. The pediatric population were evaluated preoperatively and following subtalar fusion. Seventeen feet were operated for the correction of the planovalgus foot deformity. A Holter-type microprocessor-based portable in-shoe data acquisition system was used in this study to collect the multistep dynamic plantar pressure history, while a five-camera Vicon-based gait analysis system was used to track the lower extremity joint kinematics. The results obtained from the plantar pressure measurement showed significant increases in mean peak vertical plantar pressures postoperatively at the lateral midfoot and lateral metatarsal heads. Mean contact durations and mean pressure-time integrals were also significantly increased at these plantar locations following foot surgery. This redistribution in pressure metrics suggests the formation of new lateral plantar weight bearing areas. The 3-D gait analysis system, using standardized lower extremity measurements, was unable to reveal any significant changes in joint kinematics, particularly at the foot and ankle where the surgery was performed. This suggests the need for a more refined system to track the complex motion of the pediatric foot and ankle during gait.

Adolescent↗

Instantaneous postural stability characterization using time-frequency analysis.

Postural stability assessment is critical to a more accurate understanding of sway and balance control. The center of pressure (COP) metric has been shown to be a suitable output measure for time and frequency analysis. However, the center of pressure is a non-stationary signal. Standard time and frequency analysis methods may not be adequate for monitoring the dynamic changes in the center of pressure signal. In this study a time-frequency method, based on data-adaptive evolutionary spectral estimation, is applied to monitor the dynamic changes of the center of pressure in a non-stationary environment. Metrics including the instantaneous mean frequency (IMF), instantaneous spectral bandwidth (ISB), and instantaneous average power (IAP) are analyzed to characterize the center of pressure signal in both the anterior-posterior (AP) and the medial-lateral (ML) planes. Within the confines of this study, the IMF was found to be inversely proportional to IAP. The inverse proportionality factors were calculated in both eyes-open and eyes-closed trials during upright quiet standing. These findings suggest that the time-frequency analysis provides instantaneous metrics which describe the amplitude changes and frequency shift of the center of pressure under a variety of environmental conditions, thus providing a more reliable quantification of postural control.

Adult↗

Hindfoot coronal alignment: a modified radiographic method.

Accurate clinical evaluation of the alignment of the calcaneus relative to the tibia in the coronal plane is essential in the evaluation and treatment of hindfoot pathologic condition. Previously described radiographic views of the foot and ankle do not demonstrate the true coronal alignment of the calcaneus relative to the tibia. Some of these views impose on the patient an unnatural posture that itself changes hindfoot alignment, whereas other methods distort the coronal alignment by the angle of the x-ray beam. Our purpose was to develop a modified radiographic view and measurement method for determining an angular measurement of hindfoot coronal alignment based on a cadaver study of the radiographic characteristics of the calcaneus and motion analysis of standing subjects. The view was obtained by having the subject stand on a piece of cardboard to create a foot template. The template was then positioned so that each foot was x-rayed perpendicular to the cassette while still maintaining the natural base of support. A method using multiple ellipses was developed to determine more accurately the coronal axis of the posterior calcaneus. A study using cadavers was performed in which radio-opaque markers were placed on multiple bony landmarks on the calcaneus. The tibia was held fixed in a vertical position, and the foot was x-rayed using the above techniques in different degrees of rotation without changing the relation of the calcaneus to the tibia. The radiographs of the modified Cobey and our view were examined to verify which markers were visible at different angles of rotation and how the hindfoot alignment measurements changed with foot rotation. To define further the differences between the views, an analysis of postural stability was conducted while the subjects were standing with the feet in the positions for imaging both the Buck modification of the Cobey view and our hindfoot alignment view. The combined results of the cadaver, radiographic measurement, and postural stability segments of the study reveal that this coronal hindfoot alignment view and measurement method is reproducible, more closely measures "true" coronal hindfoot alignment, and is more clinically applicable because the alignment is measured while the patient is standing with a normal angle and base of stance. The modified radiographic measurement method relies on posterior calcaneal anatomic landmarks, is less affected by rotation of the foot and ankle, and is reproducible between observers.

Adult↗

A noninvasive, three-dimensional spinal motion analysis method.

STUDY DESIGN: A three-dimensional, noninvasive motion analysis method was developed by monitoring the orientation of the principal axes of each vertebra. OBJECTIVES: To develop a method of performing three-dimensional, noninvasive motion analysis of the spine using computed tomography data. SUMMARY OF BACKGROUND DATA: The concept of using principal axes of the moment of inertia tensor to measure the orientation and position of a rigid body has been applied to the wrist and subtalar joints, but has not yet been applied to the spine. METHODS: Scans were taken of two isolated vertebrae in various known positions. Centroids, area, moments, and product of inertia of each scan were determined using a commercial program. Custom software combined data using the parallel axis theorem to give three-dimensional data for each vertebra. Changes in the centroid and principal axes were used to calculate translation and rotation, respectively. RESULTS: The system accuracy was within 1.0 degree in rotation and 1.0 mm in translation. Some errors occurred in minor motions when a smaller number of scans were used. System resolution was 0.43 mm. CONCLUSIONS: A system has been developed capable of calculating three-dimensional spinal motion based on measurements of a series of computed tomography images. The system has an accuracy similar to that of current motion analysis methods, but future studies will be necessary to apply this system in vivo.

Cadaver↗

A comparison study of plantar foot pressure in a standardized shoe, total contact cast, and prefabricated pneumatic walking brace.

Total contact casting is the current recommended treatment for Wagner Stage 1 and 2 neuropathic plantar ulcers. The rationale for this treatment includes the equalization of plantar foot pressures and generalized unweighting of the foot through a total contact fit at the calf. Total contact casting requires meticulous technique and multiple cast applications to avoid complications before ulcer healing. An alternative to total contact casting is the use of a prefabricated brace designed to maintain a total contact fit. This study compares plantar foot pressure metrics in a standardized shoe (SS), total contact cast (TCC), and prefabricated pneumatic walking brace (PPWB). Five plantar foot sensors (Interlink Electronics, Santa Barbara, CA) were placed at the first, third, and fifth metatarsal heads, fifth metatarsal base, and midplantar heel of 10 healthy male subjects. Each subject walked at a constant speed over a distance of 280 meters in a SS, PPWB, and TCC. A custom-made portable microprocessor-based system, with demonstrated accuracy and reliability, was used to acquire the data. No significant differences in peak pressure or contact duration were found between the initial and repeat SS trials (P > 0.05). Peak pressures were reduced in the PPWB as compared to the SS for all sensor locations (P < 0.05). Similarly, peak pressures were reduced in the TCC compared to the SS for all sensor locations (P < 0.05) with the exception of the fifth metatarsal base (P = 0.45). Our results are summarized as follows: (1) the methods used in the current study were found to be reliable through a test-retest analysis; (2) the PPWB decreased peak plantar foot pressures to an equal or greater degree than the TCC in all tested locations of the forefoot, midfoot, and hindfoot; (3) compared to a SS, contact durations were increased in both the TCC and PPWB for most sensor locations; and (4) the relationship of peak pressure over time, the pressure-time integral, is lower in the brace compared to the shoe at the majority of sensor locations. The values are not significantly different between the cast and shoe. These findings suggest an unweighting of the plantar foot and equalization of plantar foot pressures with both the PPWB and TCC. Based on these findings, the PPWB may be useful in the treatment of neuropathic plantar ulcerations of the foot.

Braces↗

A Holter-type, microprocessor-based, rehabilitation instrument for acquisition and storage of plantar pressure data.

A Holter-type, microprocessor-based, portable, in-shoe, plantar pressure data acquisition system has been developed. The system allows continuous recording of pressure data between the sole of the foot and the shoe during the performance of daily living activities. Fourteen conductive polymer sensors acquire the plantar pressure history, which is then stored in the system memory. Pressures are sampled at a rate of 40 Hz from each of the 14 sensors for up to 8 hrs. The extended recording and processing capacity of the system developed in this study allows quantitative analysis of cumulative plantar pressure and temporal gait data necessary for characterization of event-related alterations in plantar pressures. The alterations that could be examined with the system include rehabilitative, therapeutic, surgical, and nonsurgical treatment. The system is fully portable and does not disrupt the natural gait pattern of the subject during ambulation. Peak plantar pressures, pressure-time integrals, and contact durations are determined for each of the insole sensors.

Equipment Design↗

A system for the analysis of foot and ankle kinematics during gait.

A five-camera Vicon (Oxford Metrics, Oxford, England) motion analysis system was used to acquire foot and ankle motion data. Static resolution and accuracy were computed as 0.86 +/- 0.13 mm and 98.9%, while dynamic resolution and accuracy were 0.1 +/- 0.89 and 99.4% (sagittal plane). Spectral analysis revealed high frequency noise and the need for a filter (6 Hz Butterworth low-pass) as used in similar clinical situations. A four-segment rigid body model of the foot and ankle was developed. The four rigid body foot model segments were 1) tibia and fibula, 2) calcaneus, talus, and navicular, 3) cuneiforms, cuboid, and metatarsals, and 4) hallux. The Euler method for describing relative foot and ankle segment orientation was utilized in order to maintain accuracy and ease of clinical application. Kinematic data from a single test subject are presented.

Ankle Joint↗

A Holter-type microprocessor-based rehabilitation instrument for acquisition and storage of plantar pressure data in children with cerebral palsy.

A multichannel, portable data acquisition system has been developed to measure discrete plantar pressures in the rehabilitation of children who have cerebral palsy and planovalgus foot deformity. The microprocessor-based system is designed to be lightweight (350 g with batteries) and portable (no umbilicus) in order to minimize encumbrances to gait patterns. It provides an improved method for obtaining accurate and reliable data during extended recording and rehabilitative periods that is not available from commercial systems. Twelve conductive polymer force (pressure) sensors are used to acquire pressure data, which are then stored in the system memory. Plantar pressures are sampled at a rate of 40 Hz from each of the 12 sensors for up to 2 h. The system consists of 16 analog amplifiers, a 12 b sampling analog-to-digital converter, an 8 b Dallas semiconductor microprocessor (DS5001FP-16, Dallas, TX), 4 MB of pseudo static RAM, and serial and parallel I/O interfaces. The interfaces are used to upload data into a PC for further processing, analysis, and display. During subject testing, sensors are located at predetermined anatomic areas under the calcaneus, medial and lateral midfoot, medial and lateral metatarsal heads, and hallux. Foot pressure data has been acquired from two pediatric subjects during multiple walking trials to illustrate system application in the normal and planovalgus foot. The system is considered to be appropriate for further clinical application and for characterization of event related alterations including rehabilitative, therapeutic, surgical, and nonsurgical treatment.

Cerebral Palsy↗

An optoelectric plantar "shear" sensing transducer: design, validation, and preliminary subject tests.

A prototype miniature plantar shear sensing transducer was developed, characterized, and tested in this study. Electro-optical components were chosen for the design because of the fast response time, low cost, small size, low power requirements, and adaptability to this application. The optoelectric circuit employed a 660 nm wavelength light source and photodiode solar cell. Signal amplification and sensitivity were adjusted to provide an output voltage proportional to light power. The sensor shell was designed to encapsulate the electro-optical sensing components while providing mechanical resistance to shear through a spring mechanism. A naval bronze was chosen for the shell due to its strength and nonreflective characteristics (alloy of copper and tin). Static and dynamic characteristics of the shear sensor were determined through a series of calibration tests. Mechanical crosstalk sensitivity ranged from 14.34 to 30.51 mV/N. This represented 1% full-scale/Newton sensitivity. Nonlinearity averaged 5.6% in the forward direction and 7.6% in the reverse direction. Overall sensor output hysteresis was 1.1 +/- 3.1% while the natural frequency of the sensor to an input shear transient was approximately 5 Hz. Temperature sensitivity was -7.0 mV/degree C or 3.5% full-scale/degree C. Testing of five adult subjects revealed peak anterior-posterior shear ranging from 6.7 kPa (posterior heel) to 51.4 kPa (great toe) and medial-lateral shear ranging from 5.4 kPa (great toe) to 43.5 kPa (first metatarsal head). Stress-time integral values ranged from 0.78 kPa-sec (posterior shear at the posterior heel) to 37.3 kPa-sec (medial shear at the posterior heel). Contact durations ranged from 0.28 sec (posterior shear at the posterior heel) to 1.25 sec (medial shear at the posterior heel). Further application of the sensor for plantar shear characterization in able-bodied subjects and those with pathology is suggested.

Adult↗

Evaluation of a rehabilitative pedorthic: plantar pressure alterations with scaphoid pad application.

Scaphoid or longitudinal arch pads are frequently prescribed pedorthics for foot and ankle rehabilitation. These pedorthics are reported to be effective in mechanically supporting the medial longitudinal arch while reducing plantar and medial soft tissue strain. The objective of this study was to measure alterations in ambulatory plantar pressure metrics in a group of adults secondary to scaphoid pad application. The biomechanical rationale of this study was that the geometry of foot contact would be altered secondary to foot inversion. Ten adult male subjects with biomechanically normal feet were evaluated during multiple trials. A Holter type microprocessor-based portable in-shoe plantar pressure data acquisition system was used to record the dynamic data. Pressures were recorded from eight discrete plantar locations at the hindfoot, midfoot, and forefoot regions of the insole. Statistically significant (p < or = 0.05) increases in peak pressures were seen laterally with scaphoid pad application, while significant decreases in peak pressures with pad usage occurred at the hallux and the calcaneal region of the foot. At the medial longitudinal arch, peak pressures increased from near 0 to 115.3 kPa, contact durations increased from near 0 to 438 ms, and pressure-time integrals increased from near 0 to 33.4 kPa.s.

Adult↗

Investigation of spectral content from discrete plantar areas during adult gait: an expansion of rehabilitation technology.

Evaluation of foot contact frequency components with the use of a standard force plate has been reported to be helpful in the clinical assessment of degenerative joint disease. Spectral analysis has also been used as a tool for the evaluation of prosthetic and orthotic designs. In this paper, we examine and employ a new method for determining spectral characteristics of discrete plantar foot surface areas. This method is used to characterize spectral frequency content of foot strike at discrete plantar locations in ten normal controls. Spectral data obtained from a standard force plate are also presented and compared to reports in the literature. Measurements at six discrete points under the foot were made with a custom-manufactured strain gage-based force dosimeter. In addition, measurements of ground reaction forces in the sagittal, coronal, and transverse planes were made using a high resonant frequency force plate during barefoot and shod walks for ten adult male control subjects. Spectral frequency components of all forces measured were determined through Fourier analysis. The hypothesis of the study was that discrete plantar frequencies would be essentially similar to those reported in earlier studies of foot contact with a ground reaction force plate. While Fourier transform of time domain force plate data revealed frequency contents that were contained primarily below 10 Hz, as has been previously reported, higher frequency components associated with impulsive loading at heel strike were also observed (75 Hz for barefoot walk and 60 Hz for shod). The anterior-posterior (AP) frequency spectrum of barefoot walking contained higher amplitude components than did shod walking, though both signals contained dominant frequencies of about 1 Hz. Medial-lateral (ML) frequency analyses were similar for both walking conditions with dominant components of about 4 Hz noted. Broader frequency spectrums were seen in the discrete force dosimeter data. Components were contained mostly below 12 Hz with some higher frequency content also noted. Discrete foot force dosimeter and force plate AP and ML spectral data during ambulation have not been previously reported.

Adult↗

Walking cadence effect on plantar pressures.

OBJECTIVE: Prior studies have examined the effect of cadence on ground reaction forces by use of a force plate. Force plate studies generally analyze isolated steps and do not provide insight into ongoing step-to-step variations or in-shoe plantar pressures. The objective of this study was to evaluate the effect of walking cadences on in-shoe plantar pressures over extended periods of continuous walking. DESIGN: Nonrandomized control trial. SETTING: Laboratory. PATIENTS OR OTHER PARTICIPANTS: Volunteer sample of 8 able-bodied subjects. INTERVENTIONS: In-shoe plantar pressures were studied during four minutes of continuous walking at controlled cadences of 70, 80, 90, 100, 110, and 120steps/min. For each cadence more than 200 steps were analyzed for each of the 8 subjects. MAIN OUTCOME MEASURES: Pressure-time integrals, foot-to-floor contact durations, and peak pressures at all 14 locations were processed for each step. Changes were calculated compared to values at 70steps/min. RESULTS: With increasing cadence, mean pressure-time integrals continuously decreased (45% at 120steps/min); mean foot-to-floor contact durations continuously decreased (64% at 120steps/min); and mean peak pressures increased (119% at 120steps/min). CONCLUSIONS: Our results show that as walking cadence increases, pressure-time integrals and foot-to-floor contact durations decrease, and peak plantar pressures increase. This is clinically relevant to all kinetic gait studies because our results suggest that normal values should be established for each cadence.

Adult↗

Comparison of two fixation methods of oblique lesser metatarsal osteotomies: a biomechanical study.

Two methods of internal fixation of oblique lesser metatarsal osteotomies were compared biomechanically using fresh-frozen human cadaver bones. Osteotomies were made obliquely through the metatarsal shafts and fixed with either crossed Kirschner wires or a single AO screw using the lag technique. The specimens were then fixed at their proximal end and loaded to failure using an axial torsion material testing system (MTS, Minneapolis, MN). Load displacement curves were obtained and the stiffness of the constructs were determined. Single-screw fixation was found to be significantly stiffer than the crossed wire configuration (P < .01). Single-screw fixation resulted in a stiffness of 211.2 +/- 111.7 N/cm (mean +/- SD), while stiffness of the crossed wire configuration averaged 56.9 +/- 25.1 N/cm.

Biomechanical Phenomena↗

Plantar pressures with total contact casting.

Total contact casting has been used to aid in the healing of plantar neurotrophic ulcerations. The efficacy of total contact casts in promoting ulcer healing is presumably due to a reduction in the load over high pressure areas with pressure redistribution over the entire surface of the foot. The purpose of this study was to quantify the effectiveness of total contact casting in reducing plantar pressures. A portable microprocessor-based data-acquisition system was used for recording plantar pressures. Plantar pressures were collected from six nondisabled individuals with and without total contact casting at cast-walking cadence. In our study, there was a decrease in plantar loading under the metatarsal heads (first, fourth, fifth), the great toe, and the heel. The average decrease was 32% under the fifth metatarsal, 63% under the fourth metatarsal, 69% under the first metatarsal, 65% under the great toe, and 45% under the heel. Our study quantitatively showed that total contact casting does reduce vertical plantar pressures in high load areas.

Adolescent↗

Biomechanical and reflex responses to joint perturbations during electrical stimulation of muscle: instrumentation and measurement techniques.

A test device is developed to measure ankle joint compliance and muscle activity when the ankle is subjected to perturbations in angular position (or torque) from bias positions achieved volitionally or via electrical stimulation. The ankle measurement system uses a pivoting footplate and is operable with the subject sitting or supine. A companion platform for the knee is developed that uses a rotary arm and attached leg brace and is operable with the subject's leg in the horizontal or vertical plane. The knee fixture's pivoting arm can slide to account for the cam-like movement of the knee during rotation. The devices use similar hardware and share common instrumentation and control. Precise torque or position perturbations are delivered by a computer-controlled torque motor to the ankle or knee. Angular displacement, torque, acceleration, knee fixture moment arm and electromyographic data are collected on analogue tape and simultaneously digitised and stored. A special stimulator/recording amplifier permits the recording of electromyographic signals from the stimulated muscle. Experimental data indicate that the ankle and knee devices, operated horizontally, are purely inertial systems. Sample ankle and knee joint responses to perturbations are presented.

Ankle Joint↗

Comparison of stability of proximal crescentic metatarsal osteotomy and proximal horizontal "V" osteotomy.

Proximal metatarsal osteotomies are often performed in patients with hallux valgus and significant metatarsus primus varus. The crescentic osteotomy is popular; however, some authors have reported malunion of the metatarsal shaft caused by dorsal angulation of the osteotomy in a significant number of cases. Recently, proximal transverse "V" osteotomies have been reported to have good results, with rapid healing and no dorsal malunions. We compared the stability of a transverse, proximal "V" osteotomy, using two 0.062-inch K-wires or a 3.5-mm cortical screw for fixation, with that of the proximal crescentic osteotomy, using a 3.5-mm cortical screw fixation. The three osteotomy/fixation techniques were performed on 30 fresh-frozen cadaver feet. The specimens were loaded to failure at the fixation site by applying a load through the plantar surface of the first metatarsal head. Force versus displacement curves were obtained to calculate the failure load and stiffness. Statistical differences among the three groups were determined by the nonparametric Mann-Whitney U-test and the standard t-test. The "V" osteotomy/screw group was more stable than either the "V" osteotomy/pin group or the crescentic osteotomy/screw group. Differences in failure strength between the "V"/screw group and the other two groups were significant at the P < .01 level and the differences in stiffness were significant at the P = .05 level. No statistical differences were found between the "V"/pins and the crescentic/screw groups.

Biomechanical Phenomena↗

Multistep measurement of plantar pressure alterations using metatarsal pads.

Metatarsal pads are frequently prescribed for nonoperative management of metatarsalgia due to various etiologies. When appropriately placed, they are effective in reducing pressures under the metatarsal heads on the plantar surface of the foot. Despite the positive clinical reports that have been cited, there are no quantitative studies documenting the load redistribution effects of these pads during multiple step usage within the shoe environment. The objective of this study was to assess changes in plantar pressure metrics resulting from pad use. Ten normal adult male subjects were tested during a series of 400-step trials. Pressures were recorded from eight discrete plantar locations at the hindfoot, midfoot, and forefoot regions of the insole. Significant increases in peak pressures, contact durations, and pressure-time integrals were noted at the metatarsal shaft region with pad use (P < or = .05). Statistically significant changes in metric values were not seen at the other plantar locations, although metatarsal pad use resulted in mild decreases in mean peak pressures at the first and second metatarsal heads and slight increases laterally. Contact durations decreased at all metatarsal head locations, while pressure-time integrals decreased at the first, second, third, and fourth metatarsal heads. A slight increase in pressure-time integrals was seen at the fifth metatarsal head. The redistribution of plantar pressures tended to relate not only to the dimensions of the metatarsal pads, but also to foot size, anatomic foot configuration, and pad location. Knowledge of these parameters, along with careful control of pad dimensions and placement, allows use of the metatarsal pad as an effective orthotic device for redistributing forefoot plantar pressures.

Adult↗