An equation for computing expected birth measurements (including birthweight) for the Turkish population (based on pregnancy characteristics).
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Adolescent↗
Biomedical subjects
G Erdem
Publications and source records attributed to G Erdem.
Blood ammonia levels in premature and full-term infants.
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Ammonia↗
A case report of hyaline membrane disease with rare complications.
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Adult↗
The use of IgM-enriched intravenous immunoglobulin for the treatment of neonatal sepsis in preterm infants.
The value of IgM-enriched immunoglobulin therapy in 44 preterm infants with neonatal sepsis was evaluated in a prospective randomized study. All infants received antibiotic therapy and fresh plasma and/or whole blood transfusions. Twenty randomly-chosen infants were allocated to receive 5 ml/kg/d of IgM-enriched immunoglobulin intravenously for three days. Although the mortality rate in preterm infants whose gestational ages were 31-34 weeks in the immunotherapy group was slightly lower than in the control group, the general mortality rate from sepsis in the control group (9/24) and in the immunotherapy group (6/20) showed no statistically significant difference (37.5% vs 30.0%, p < 0.05).
Anti-Bacterial Agents↗
Plasma chromium levels in small-for-gestational-age newborn infants.
Plasma chromium (Cr) levels were determined in 24 preterms and 18 full-term newborn infants. There was no statistically significant differences in plasma Cr levels between the preterm and full-term infants. Plasma Cr levels were similar in small-for-gestational-age infants and in infants with hypoglycemia compared with healthy infants.
Birth Weight↗
Systemic lupus erythematosus presenting with thrombocytopenia. Report of a child with positive anticardiolipin antibodies.
We report a case of systemic lupus erythematosus initially presenting with thrombocytopenia and diagnosed as immune thrombocytopenic purpura. The patient subsequently developed lymphadenopathy, arthritis and cardiac involvement along with anticardiolipin antibodies. We would like to emphasize the fact that these autoantibodies have a role in the pathogenesis of thrombocyte destruction, and that patients with immune thrombocytopenic purpura should be followed for signs of systemic lupus erythematosus.
Antibodies, Anticardiolipin↗
Multiple intracranial tuberculomas in a child.
Intracranial tuberculomas continue to be a serious complication of central nervous system tuberculosis. Tuberculomas are conglomerates of tubercles resulting from hematogenous spread of infection. Modern neuroimaging studies such as magnetic resonance imaging and molecular biologic techniques such as polymerase chain reaction are helpful in the diagnosis of central nervous system tuberculosis and tuberculomas. We report a boy with multiple intracranial tuberculomas diagnosed and treated with the aids of magnetic resonance and polymerase chain reaction techniques.
Adolescent↗
Diagnosis of childhood tuberculosis by polymerase chain reaction.
The polymerase chain reaction (PCR) using oligonucleotides based on the repetitive sequence (IS6110) of Mycobacterium tuberculosis as a primer was evaluated for detection of M.tuberculosis in clinical samples. We tested 55 clinical specimens from patients suspected of having tuberculosis and 71 specimens from control subjects. PCR was more sensitive than culture (positivity rate was 14.5% and 36.3%, respectively, in suspected patients). This approach to the diagnosis of tuberculosis is a valid diagnostic alternative to classical procedures.
Adolescent↗
Relationship between maternal and neonatal iron stores.
In this study, hemoglobin (Hb), mean corpuscular volume (MCV) and serum ferritin (SF) levels were measured in 76 neonates and their mothers at delivery. Infants were grouped according to their gestational ages. Group I (< 34 weeks), group II (34-37 weeks) and group III (> 37 weeks) consisted of 15, 33 and 28 infants, respectively. Blood studies were repeated at two months of age in 50 neonates (26 from group II and 24 from group III). Among the three groups of infants, SF levels were lowest in group I, and among mothers, Group III had the lowest levels. There were positive correlations between maternal and neonatal SF levels in groups II and III. There was no difference between the SF levels of neonates born to mothers with depleted or adequate iron stores. Anemia with a normal SF level was present in 14.4 percent, subclinic iron deficiency (normal Hb and low SF level) in 11 percent and iron deficiency anemia (low Hb and low SF levels) in 7.8 percent of the mothers. At two months of age 38.4 percent of preterm and 16.6 percent of term infants had Hb concentrations less than 10 g/dl. Only one of these infants had a low SF level. There was a negative correlation between maternal SF levels and the Hb concentration of term infants at two months of age.
Erythrocyte Indices↗
Hepatic mucormycosis in a child with fulminant hepatic failure.
Mucormycosis is an uncommon, opportunistic infection in children. We present a case of fulminant hepatic failure with hepatic mucormycosis. Although the suggested defects and pathogenic mechanisms in infections related to hepatic failure and mucormycosis are similar, few cases with both mucormycosis and liver failure have been reported.
Autopsy↗
Tumor necrosis factor-alpha and interleukin-1 beta levels in children with bacterial, tuberculous and aseptic meningitis.
Cerebrospinal fluid levels of tumor necrosis factor-alpha and interleukin-1 beta in 78 children with nonbacterial, bacterial and tuberculous meningitis, and in 34 control subjects were analyzed in order to evaluate the involvement of these cytokines in the pathogenesis of acute bacterial meningitis and their discriminative value between different etiologies of meningitis. Tumor necrosis factor-alpha and interleukin-1 beta levels were significantly higher in bacterial and tuberculous meningitis than in aseptic meningitis and in control subjects (p < 0.0001). There was no difference in the levels of tumor necrosis factor-alpha and interleukin-1 beta between nonbacterial meningitis and control groups. The finding that both tumor necrosis factor-alpha and interleukin-1 beta are increased in the cerebrospinal fluid of patients with bacterial and tuberculous meningitis whereas normal levels of these two cytokines have been found in patients with nonbacterial meningitis signifies that these cytokines may be used to differentiate between bacterial and nonbacterial meningitis.
Acute Disease↗
Serum malondialdehyde concentration as a measure of oxygen free radical damage in preterm infants.
Lipid peroxidation was measured in 35 preterm infants by determining serum malondialdehyde (MDA) levels during the fist week of life. Serum concentrations of MDA were measured at one hour, 24 hours, 48 hours and one week of age. There were no correlations between gestational age, birth weight, and serum malondialdehyde levels at one, 24, or 48 hours, or on day seven. Serum MDA levels were higher in infants requiring mechanical ventilation compared to those breathing spontaneously, but the difference was not statistically significant. There were no correlations between MDA levels and corresponding fraction of inspired oxygen (FiO2) levels and arterial oxygen tension. No significant difference in serum MDA concentration was seen in relation to intravenous feeding with lipid emulsions. Serum MDA concentrations of infants with sepsis were not different at hours one, 24 and 48, but were significantly higher on day seven, when compared with infants without sepsis. MDA levels in the first and second serum samples were significantly higher in infants who were born after spontaneous vaginal delivery, compared to those born by cesarean section.
Age Factors↗