[Results of the radiofibrinogen test using a simple measuring technic].
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Biomedical subjects
Publications and source records attributed to G Endert.
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Hemodynamic evaluation of coronary artery stenosis is indicated in patients with ischemic heart disease. For this purpose myocardial perfusion scans are performed. In our study myocardial scans were performed by selective injection of 60 to 80 muCi of (131)I-MAA in the right coronary artery and of 3 mCi of (99m)Tc-microspheres in the left coronary artery. Four views (RAO, LAO, AP, LLAT) were taken with an Anger-Camera and a computer-control-led color-coded display system (Picker Dyna-Came-ra 3C/12 and Kruppe Atlas Elektronik EPR 1100, medium energy collimator). Right and left coronary artery perfusion images were stored and two-colour image produced. Following computer processing (smoothing, normalization) the images were added and photographed in color. In comparision with scans and left-ventricular and coronary angiography the sensitivity of the nuclear medicine method was shown in cases with reduced perfusion. Therefore the perfusion scans seem to be useful in combination with angiography for the determination of therapy.
It is reported on 250 needle biopsies of the thyroid gland above all in scintigraphically cold nodes. In altogether 57% of the patients either a fully inconspicuous cell picture or degenerative findings not suspicious for malignity were present. In 28% of the cases a cyst of the thyroid gland was the result. Four tumours were cytologically established; a small carcinoma in a large nodular struma was not recognized by puncture. According to corresponding opinions the needle biopsy of the thyroid gland is a valuable supplementation of the ambulant diagnostics of the thyroid gland.
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On the basis of a casuistic contribution is referred to the rare, hitherto not clarified clinical picture of the idiopathic hypertrophic osteoarthropathy (pachydermo-periostosis, Touraine-Solente-Golé syndrome). In pronounced cases the diagnosis can easily be made, when pachydermia, drumstick-fingers with watch-glass nails and hyperostotic changes of the skeleton are present. Differential-diagnostic difficulties concerning the osteoarthropathie hypertrophiante pneumonique (P. Marie-Bamberger) are the result as in the present case in abortive forms of the syndrome.
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The primary retroperitoneal tumours-a rare, but histologically very extensive group of above all malignant tumours-only late appear with their symptoms. Though with the help of the modern radiological investigation methods the proof of a tumour is frequently successful, so in special cases a coordination to organs may make great difficulties also when the total diagnostic spectre is used. These problems shall be shown by the demonstration of a case report.
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A modified method for labeling erythrocytes with 99mTc-sodium pertechnetate for spleenic scintigraphy is described. In vitro investigations have shown that by omitting the customary process of washing and by simultaneous alteration of the erythrocytes during the tin incubation period, the duration of erythrocyte labeling can be considerably reduced. A yield of 96 of 98% can be achieved. The effect of the tin on the erythrocytes is further investigated. The effect of the incubation period and temperature, of the plasma in the erythrocyte suspension, of stirring and agitation, of the dispersion liquid and tin concentration were studied. The method proves satisfactory in 56 controlled spleenic scintigrams.
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Five cases are reported where under curative aspects the splenic region was irradiated during radiation therapy of lymphogranulomatosis. In the course of this treatment, a radiation load amounting to 3000 up to 4200 R focal dose occurred to the upper pole of the left kidney. A LESION OF THE LEft kidney was diagnosed not earlier than nine or twelve months afterwards in three of the patients. Two patients could be followed up as yet only four or five months. As for verification of the circumscribed radiogenic nephritis, renal scintigraphy proved the best technique to provide information. Short-term check-up examinations are necessary for the purposes of early recognition and efficient therapy of this complication, the prognosis of lymphogranulomatosis being on the whole relatively good.
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