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Biomedical subjects

G Ekelund

Publications and source records attributed to G Ekelund.

47 records · Page 3Linked to original sources

Antibiotic prophylaxis in colorectal surgery. doxycycline compared to a combination of benzylpenicillin and streptomycin. A preliminary report.

The aim of the study was to evaluate the effect of two different regimens of antibiotic prophylaxis in colorectal surgery. The study comprises 57 consecutive cases. The mechanical preoperative preparation was essentially the same in all cases and the operative technique was standardized as far as possible. Antibiotic prophylaxis was started immediately before surgery and continued for three days postoperatively. Thirty-six patients received doxycycline 200 mg i.v. per day and 21 patients were given benzylpenicillin 10 million I.U. 4 times a day and streptomycin 500 mg twice a day. No major infectious complications (e.g. septicaemia, abscessess) were seen in either group. There were three wound infections in the doxycycline group and four in the penicillin-streptomycin group.

Adolescent↗

Histopathological analysis of benign polyps in patients with carcinoma of the colon and rectum.

All benign polyps in a 10-year series of 960 patients with colorectal carcinoma from a defined population were analysed. All cases where histological specimens of the polyps were available were reclassified according to morphological type and grade of differentiation. The findings lend support to the assumption of a relationship between benign epithelial neoplasms and adenocarcinoma of the colon and rectum.

Adenoma↗

Crohn's disease confined to the appendix.

Crohn's disease confined to the appendix is a rare entity, less than 50 cases having been reported. The present study reports on another 12 cases representing 6 per cent of all 194 patients operated upon for Crohn's disease in a total, unselected series. The indications for surgery were appendicitis in eight patients, appendiceal abscess in two, suspected pyosalpinx in one, and an ovarian cyst in one. The appendices were in all cases strikingly enlarged. Giant-cell granulomas, without microabscesses were detected in all but one patient. Two patients had early septic postoperative complications. Fistulization from the cecum did not occur. The median observation time after operation was 13.8 years. Since none of the patients had further manifestations of the disease, it is concluded that patients with Crohn's disease confined to the appendix have a favorable prognosis.

Adolescent↗

Perianal Paget's disease.

A case of extramammary, perianal Paget's disease with underlying rectal carcinoma is presented. The importance of awareness of the condition is stressed and the diagnosis and treatment are commented upon.

Adenocarcinoma↗