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Biomedical subjects

G Edelson

Publications and source records attributed to G Edelson.

13 recordsLinked to original sources
PubMed1999

[Relapse of sarcoidosis after alternative medical treatment].

Reference to alternative medicine frequently appears in newspaper headlines, advertisements and in articles in medical journals. The practice of alternative medicine has increased, even as the number of critical articles warning of deleterious effects have also increased. Public demand is strong and growing, but there are no clear rules as to what is not permissible, particularly when treatment is not by qualified physicians. There are still no clear indications and contraindications for complementary (not alternative) medicine in patients with organic injuries and life-threatening conditions. However, it is obvious that in these patients complementary medicine should not be substituted for conventional therapy. We present a 32-year-old man with sarcoidosis who discontinued conventional therapy on his own initiative and began alternative medicine (homeopathy) with subsequent deterioration in his condition. He was hospitalized for a relapse of his sarcoidosis which required large doses of corticosteroids.

Adrenal Cortex Hormones↗
PubMed1997

[Infection by Vibrio vulnificus after a prick from from the spine of a Tilapia].

Vibrio vulnificus is a Gram-negative bacterium living in warm salty water that produces a spectrum of human disease which may progress to devastating, sometimes fatal infections in susceptible individuals. Such infections have rarely been reported in Israel. However, over the past few months we have been seeing a sharp increase in V. vulnificus infections with a common history of injury to extremities by the sharp spines of Tilapia zillii, ("amnon" or St. Peter's fish). Clinical suspicion and prompt intervention prevent the untoward consequences of misdiagnosis or delay.

Adult↗
PubMed1993

Pyknodysostosis: imaging and laboratory observations.

Pyknodysostosis is a rare form of sclerosing bone dysplasia with autosomal recessive inheritance. Affected members of two families were assessed as follows: three patients underwent densitometry measurements and bone scans; four patients underwent magnetic resonance imaging (MRI) and an immunological investigation, as well as a detailed endocrinological and biochemical laboratory review. Densitometry measurements revealed values of up to 291% of age-matched normal controls; this increased bone density was mainly in the trabecular bone and not in the cortical bone. The MRI showed the cortex to be of normal thickness, whereas the increase in trabecular bone limited the space within the medullary canal. Bone scans and single photon emission computerized tomography in three patients showed an increased uptake of [99mTc]methylene diphosphonate of up to 538% of age-matched controls, which reflected the increased bone density. Monocyte function tests demonstrated a normal phagocytic capacity, but their killing activity was impaired. Interleukin-1 secretion was also impaired, which may point to the pathogenesis of the disease, in view of its function as an osteoclast activator and its role in bone resorption.

Adolescent↗
PubMed1993

Suprascapular nerve palsy in a young athlete.

Palsy of the suprascapular nerve may be easily overlooked in the differential diagnosis of the painful shoulder. Although the diagnosis is well documented in the literature, opinion is still divided regarding its etiology and treatment. This case report offers an example of successful nonoperative management of a suprascapular nerve palsy which followed an acute episode of muscular stress in a young male athlete.

Acute Disease↗
PubMed1991

Possible congenital hemolytic anemia in prehistoric coastal inhabitants of Israel.

The spread of thalassemia among prehistoric populations of the Mediterranean Basin has been linked to the increased risk to early agriculturalists posed by the Plasmodium falciparum parasite. The diagnosis of the disease in human skeletal remains, however, has usually been based on a single pathological criterion, porotic hyperostosis. This paper reports on what we believe to be the earliest case of thalassemia yet identified in the prehistoric record. Our diagnosis of the disease in an individual from the submerged Prepottery Neolithic B village of Atlit-Yam off the Israeli coast is based on a pathological humerus demonstrating a pattern of deformation characteristic of clinical thalassemia. The implications of these findings for our understanding of human societies undergoing the transition from foraging to agriculture in the Near East are discussed.

Anemia, Hemolytic, Congenital↗
PubMedDate not supplied

Variations in the retroversion of the humeral head.

It is generally accepted that the humeral head in adults is retroverted between 25 degrees and 35 degrees. To assess the validity of this belief, 336 dry bone specimens of humeral heads were measured. The specimens were taken from various ethnic groups: white Americans, black Americans, New Mexican Indians, northern Chinese, Alaskan Eskimos, and Negev Desert bedouins. There was significant variation in retroversion angle between specimens from different ethnic groups and even wider variation between specimens within particular groups--a finding contrary to popular belief. Retroversion angle in the specimens ranged from -8 degrees to +74 degrees. In addition, 50 fetal skeletons of white and black Americans were studied. The mean humeral head retroversion angle in the fetal skeletons was 78 degrees, much greater than that in adults. It was evident that the large retroversion angle in the very young decreases with growth and that it does so to a varying extent among different ethnic groups and individuals. It is of clinical importance to understand the variations in humeral head retroversion among individuals undergoing operation and the ways in which this parameter might be manipulated to surgical advantage.

Adult↗
PubMedDate not supplied

Internal impingement in the shoulder.

Current wisdom holds that the acromion is a major factor in the development of rotator cuff impingement. From the examination of a large number of skeletal specimens (1232 shoulders), we conclude that this view may require some modification. It appears that internal impingement between the glenoid and the humeral head may also be a significant mechanism in the development of rotator cuff pathosis. We present here the evidence for this internal impingement, which is expressed in characteristic telltale patterns impressed into the bones on both sides of the joint. If this thesis is correct, the rationale for some acromioplasty operations may be called into question, currently the most popular procedure in shoulder surgery.

Acromion↗
PubMedDate not supplied

The development of humeral head retroversion.

Humeral head retroversion is important in a variety of clinical situations, but it is not known when retroversion actually develops to adult values. In utero and at birth, the humeral head is known to be in marked retroversion. It derotates sometime thereafter to assume the more standard value with which orthopedic surgeons are familiar. By studying a unique collection of children's bones (180 humeri), I have been able to determine that the greater part of this process takes place, on average, by the age of 8 years (SD +/- 2.12 years); from then on, however, the development continues more slowly until the final adult dimensions are reached, as heralded by the appearance of the radial groove at approximately 16 years of age. This process, along with its timing, appears to be similar, but opposite in direction to, the derotation process that is known to take place in the hip. It has not previously been documented in the shoulder.

Adolescent↗
PubMedDate not supplied

Bony changes at the lateral epicondyle of possible significance in tennis elbow syndrome.

Examination of a large number (1232) of elbows from skeletal specimens revealed that 16% displayed a characteristic pattern of bone formation exactly underlying the area of exquisite point tenderness at the lateral humeral epicondyle found in clinical cases of tennis elbow. These changes are usually not seen on standard roentgenograms and can be missed, even at the time of surgery, because this area is not commonly exposed in standard tennis elbow approaches. In a group of clinical cases of tennis elbow (20 patients), similar bony changes could be demonstrated in the majority (60%) of patients with chronic tennis elbow symptoms by the use of specialized x-ray techniques-most notably, coronal reconstructions with computed axial tomography. Ten cadaver specimens were also dissected to delineate the muscular and capsulotendinous insertions in this area. We call attention to these bony changes in the supposition that they may be involved in the development and persistence of symptoms in tennis elbow.

Adult↗