Search PubMed⌕ Search

Biomedical subjects

G E Dryden

Publications and source records attributed to G E Dryden.

18 recordsLinked to original sources
PubMed1986

Voluntary respiratory effects of butorphanol and fentanyl following barbiturate induction: a double-blind study.

Thirty-one healthy women undergoing outpatient gynecologic surgery were given either butorphanol or fentanyl following barbiturate induction, and various respiratory parameters were measured at intervals after administration of the study drugs. Both fentanyl and butorphanol caused comparable decrements in tidal volume and other respiratory parameters. However, seven of the 15 patients receiving fentanyl had significant respiratory depression that required assisted ventilation. One of the butorphanol patients experienced a 45-second self-limited respiratory depression. One of three butorphanol patients experiencing side effects required treatment for these effects, compared with seven of nine fentanyl patients who experienced adverse effects. It is concluded that butorphanol and fentanyl have comparable anesthetic effects, but butorphanol is safer in terms of respiratory and adverse effects.

Adolescent↗
PubMed1980

Performance of bacteria filters.

Several kinds and brands of bacteria filters are commercially available for use in anesthesia and respiratory therapy applications. Clinical experience of high airflow resistance, ruptured media, failure to retain visible dust particles, and lack of consistent performance statements or warranties by manufacturers about their bacteria filters prompted a study of the performance of 13 different filters. The filters were challenged by mineral oil droplets, Serratia marcescens and Excherichia coli bacteriophages T4 and T7, tobacco smoke, nebulized india ink, dioctylphthalate smoke (DOP), and water. Results showed that viable bacterial passed through some filters, many filters were unable to retain visible ink or tobacco smoke particles, and resistance to airflow was increased two-fold or more in many filters when the filters were laden with 10 ml of water. Conflicting data resulted from two different types of DOP testing machines. There was a wide variation in performance among the different brands of filters; variable results also were seen within a given brand. Five brands of filters met the federal DOP standards for HEPA filters, but the wide variation in DOP testing results with two different kinds of DOP machines indicates a need for better standards. The DOP 0.3-micron bubble test is the most readily available nontoxic test to rate filtration efficiency; however, the DOP efficiency rating cannot be used to equate equivalent performance against infectious organisms.

Anesthesiology↗