The value of the EEG in the diagnosis of localized epilepsies in children.
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Adolescent↗
Biomedical subjects
G Dumermuth
Publications and source records attributed to G Dumermuth.
EEG data acquisition and preprocessing by microcomputer satellite system.
Recent development in computer technology allows already medium scale EEG data processing to be performed within the clinical neurophysiology department, if a fast minicomputer with adequate mass storage and graphical output facilities is used. Data acquisition, however, should be delegated to a microcomputer which also should take over as much preprocessing as possible. A system is presented, where one or several microcomputer-based satellite units perform analog-digital conversion, Fourier transformation (FFT), calculation of power spectra and crossproducts, as well as event related averaging or other preprocessing procedures. The units are connected to a fast central minicomputer, where a supervisor program loads the microprocessors with their programs, supervises their activity, receives preprocessed data and activates appropriate postprocessing programs to produce the final results.
Analog-Digital Conversion↗
The computation of EEG bispectra.
This paper presents a FORTRAN program for computation of bispectra of multichannel EEG on a PDP-11/55 computer. Input data are already digitized and file-structured. Output of power spectra, bicoherence and biphases is produced in synoptic form on a line printer.
Computers↗
Nonketotic hyperglycinemia treated with strychnine, a glycine receptor antagonist.
A 6 1/2-month-old boy suffering from nonketotic hyperglycinemia has been treated for at least 12 months with oral strychnine. The drug caused improvement of muscle tone, motoricity, vigilance and social behavior. Glycine is one of the putative neurotransmitters of postsynaptic inhibition, particularly at the spinal and reticular levels, strychnine its antagonist at the postsynaptic membrane. Strychnine improved the patient's motoricity presumably by blocking the excessive glycine-mediated inhibition of motoneurons. The beneficial effect of strychnine on vigilance and social behavior is more difficult to explain but may have been related to its antagonism of glycine inhibition of brainstem reticular neurons.
Amino Acid Metabolism, Inborn Errors↗
Studies on EEG activities in the beta band.
A report on first findings of quantitative investigations of beta activity in the frequency domain is presented. Spectral analysis techniques were applied in three parallel still ongoing clinical studies, i.e. (1) an exploration of beta activities in a broad clinical material, (2) a study of the possible use of quantitative beta assessment in antiepileptic drug therapy, and (3) an investigation of special patterns with harmonic components in the beta band. Several clearly distinguishable types of spectral shapes, different coherence characteristics, significant alterations by changes of drug composition and a rich variation of harmonic patterns indicate a large and fascinating new field for clinical EEG research.
Adolescent↗