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Biomedical subjects

G Duc

Publications and source records attributed to G Duc.

At least 109 records · Page 6Linked to original sources
PubMed1976

[The dyspnea syndrome of the newborn in Switzerland. Results of a cooperative study within the framework of the Swiss Neonatology Group].

The Swiss Neonatology Group was founded in 1972 to strengthen cooperation between obstetricians and pediatricians in this country. To this end a collaborative study was made of the incidence of respiratory distress syndrom in Switzerland during 1974. Almost every neonatal unit of the country participated, and the study thus covered the problem cases taken from approximately 90% of all Swiss newborns. 30% of the newborns hospitalized in neonatal units (or 2% of all Swiss newborns) developed a respiratory distress syndrome. 16% of these died. One third of all the cases of respiratory distress and two thirds of the deaths were due to hyaline membrane disease, which mainly occurred in prematures. The other cases of respiratory distress were divided between aspiration, transient respiratory distress and other pulmonary disorders. 31% of the newborns with respiratory distress syndrome underwent mechanical ventilation, more than half of these having hyaline membrane disease. The success already achieved by modern perinatology looks hopeful for the future.

Humans↗
PubMed1976

[Herpes simplex encephalitis in newborns. Treatment with 5-iodo-2'-deoxyuridin? (author's transl)].

Premature twins both affected with generalized herpes simplex infection including CNS involvement were treated with 5-Iodo-2'-deoxyuridin (IDU). Therapy was started 6 days and 5 days, respectively, after appearance of the first symptoms. Nevertheless both babies died, twin A at the age of 24 and twin B at the age of 28 days. Herpes virus was cultured from all organs in twin A. The literature shows a decrease in mortality in children treated with IDU for herpes simplex encephalitis. The percentage of survivors with ultimate severe CNS damage, however, is very high and remains in treated or untreated patients the same. The institution of IDU therapy in neonates with manifest HSV encephalitis is therefore not unequivocally justified.

Encephalitis↗
PubMed1976

Transcutaneous PO2 monitoring in routine management of infants and children with cardiorespiratory problems.

Results are reported concerning the clinical application of the transcutaneous PO2 method (tc PO2 method) according to Huch et al. for monitoring arterial PO2. Thirty long-term continuous tc PO2 recordings were made in 22 ventilated children and infants with cardiorespiratory problems in four different pediatric intensive care units (Zürich, Göttingen, Kassel, and Mainz). These recordings were compared with 132 arterial PO2 determinations made during the same period of time. There was a linear relationship and a close correspondence between arterial PO2 and tc PO2 (r = .94). The continuous recordings have shown that the variability of PO2 is much greater than assumed so far by single blood gas analysis. This fact restricts greatly the value of single samples. Continuous tc PO2 monitoring has proved to be a great help in optimal respirator setting.

Child↗