A preliminary study of vector control with polystyrene beads in Recife, Brazil.
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Animals↗
Biomedical subjects
G Dreyer
Publications and source records attributed to G Dreyer.
Detection by ultrasound of living adult Wuchereria bancrofti in the female breast.
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Adolescent↗
[Transplacental passage of Wuchereria bancrofti microfilariae in newborns of microfilaremic mothers].
The occurrence of circulating Wuchereria bancrofti microfilariae was investigated in 304 pregnant women from the "Unidade Mista Pof. Barros Lima" and "Hospital das Clínicas/UFPE". The filtration technique was employed to detect microfilaraemia during pregnancy, and 13 women were found to be positive (4.2%). The investigation of microfilariae in the cord blood of their children was negative (6/13), and also in venous blood samples collected up to 72 hours after birth and with 6 months of life. Milk samples from these mothers also had no microfilariae. The authors suggest that the occurrence of placentary lesions may be a possible factor involved in the transplacental transfer of microfilariae, and that in utero exposure to microfilariae and/or filarial antigens may influence the response to a filarial infection acquired later, thus being important a clinical and laboratorial follow-up of children exposed previously to filarial antigens during early periods of human development.
Adolescent↗
[Evaluation of the indirect immunofluorescence test for the diagnosis of bancroftian filariasis using microfilariae W. bancrofti as the antigen, in Recife-PE, Brazil].
The authors analysed the indirect immunofluorescence assay, for the diagnosis of bancroftian filariasis using papain treated W. bancrofti microfilariae as antigen, widely used in Recife-Brazil. Sera from 50 patients with several clinical forms of the disease including asymptomatic carriers, tropical pulmonary eosinophilia, elephantiasis, filarial fever and chyluria were analysed. For the control group, 50 individuals were selected, living at least 5 years in endemic area, with neither previous DEC treatment nor clinical-laboratory evidences of the disease, called normals endemic. The sensitivity and specificity were analysed taking into account different cut off values. It was not possible to differentiate infected individuals from the control group. It was not even possible to establish any correlation with IMF titers among different clinical presentation of the disease. Crossed reactions with various intestinal helminths were considered, but no relationship was found.
Adolescent↗
[Clinical manifestations of lymphatic bancroftian filariasis].
A review of clinical manifestations of bancroftian filariasis, based on the literature and in the authors' experience, suggests a general classification in to six groups: 1) Normal endemics; 2) Individuals bearing microfilaremia; 3) Acute manifestations; 4) Chronic manifestations; 5) Tropical Pulmonary Eosinophilia; 6) Controversial forms. An overview on diagnostic procedures and the immunologic relationship between host and parasite was made in each group. Final considerations about treatment was also considered.
Animals↗
[The importance of Strongyloides stercoralis revisited].
Strongyloidiasis is a worldwide parasitic disease and of great importance in Brasil. Among the diverse species of Strongyloides, only the following are of importance to man: S. stercoralis, S. fulleborni and S. fullerboni-like. Eventhough S. stercoralis is an intestinal helminth, strongyloidiasis is a systemic infection that can affect, beside the gastrointestinal tract, lungs, CNS, liver and biliary tract, pancreas, genitourinary tract and skin. The great majority of cases are asymptomatic, having a chronic and benign course. Among the symptomatic subjects, the gastrointestinal and pulmonary symptoms prevail. For unknown reasons, strongyloides infection may result in severe, disseminated disease. Immunosuppressive, therapy was identified as an important risk factor for disseminated illness. Diagnosing strongyloidiasis may be difficult, and eventhough the parasitological stool examination is the most used diagnostic test, sometimes larvae cannot be identified. Immunodiagnosis is not yet assessible for routine usage and is still a subject of research. Thiabendazole remains the drug of choice for treatment of strongyloidiasis, but other drugs, such as ivermectin, have been used. The purpose of this paper was to review the important aspects of the S. stercoralis infection in man.
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[Tropical filarial pulmonary eosinophilia and its differential diagnosis].
The authors present a comprehensive review of Tropical Pulmonary Eosinophilia (TPE) of filarial etiology and describe its differential diagnosis with similar syndromes. Epidemiological, clinical, diagnostic, therapeutic and phisiopathological aspects are considered, with an emphasis on new advances in our knowledge of lymphatic filariasis and their implication for improved understanding of TPE and similar syndromes. A TPE-like syndrome, which is caused by intestinal helminth infections, occurs in filariasis-endemic and non-endemic areas alike. The authors suggest guidelines for interpreting epidemiological, clinical, laboratory, radiologic (including ultrasonographic) and therapeutical data and properly diagnosing TPE syndromes. This guidelines also should be useful for physicians in areas where filariasis is not endemic but to which patients from endemic area (e.g., Greater Recife-PE, Maceió-AL and Belém-PA) frequent migrate.
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