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Biomedical subjects

G Ditscherlein

Publications and source records attributed to G Ditscherlein.

At least 55 records · Page 3Linked to original sources
PubMed1976

[Clinical aspects of glomerulonephritis].

With the help of 260 bioptically ascertained cases of glomerulonephritis clinical characteristics for individual forms of glomerulonephritis are explained. Specific laboratory findings and functional tests are correlated to the bioptic findings and their valency for the individual groups of diagnosis discussed. As a result of the investigation 99% of all cases of disease may be recognized only by the examination of the urine, taking into consideration the interference of the individual symptoms.

Biopsy↗
PubMed1976

Comparison of the results of semi-thin sections with those of conventional paraffin histology and immunohistology in renal biopsy specimens.

One hundred renal biopsy specimens out of the routine material were investigated by the usual paraffin technique, by semi-thin sections and by the immunofluorescence technique. The findings were compared in regard of the diagnoses made by each technique. The results indicate that the paraffin technique is inadequate in a considerable proportion of the specimens, because very small glomerular lesions cannot be recognized. The semi-thin section technique enabled us to correct the light-microscopic diagnosis in 17 per cent, particularly in establishing membranous glomerulonephritis. In another 31 per cent the histologic diagnoses could be improved. The immunofluorescence technique provided evidence of active glomerulonephritis in 57 per cent (24 cases with immune complex nephritis and 3 cases with basement membrane antibody nephritis). We found a much closer correlation between results of the semi-thin section technique and immunohistology that between the paraffin technique and immunohistology.

Adolescent↗
PubMed1976

[Glomerulopathy in rheumatic patients due to penicillamine].

This paper describes four cases (where rheumatoid arthritis is the basic ailment of the patients involved) of immune complex nephritis and stage I membranous glomerulonephritis, respectively. Treatment was by means of penicillamine. Also discussed are light-microscopical, immunohistological, and electron-optical results.

Adult↗
PubMed1976

[Membranous glomerulonephritis and renal vein thrombosis (author's transl)].

A report on 3 autopsy cases is given, in 2 of them a combination of membranous glomerulonephritis (mGn) and bilateral renal vein thrombosis was detected, while the third case showed a combination of mGn and large pulmonary thrombembolism being in organisation. In semithin sections characteristic spikes were seen on the external surface of the glomerular basement membrane. An immunecomplex nephritis (type:transmembranous glomerulopathy) was observed in both kidneys examined by immunofluorescence technique. The pathogenetic correlations between mGn and renal vein thrombosis are unclear so far; the two main conceptions found in the literature are discussed. The knowledge of a combination between mGn and renal vein thrombosis has practical value. The findings of mGn in a renal biopsy specimen should the clinican cause to think of the possibility of renal vein thrombosis. On the other hand a renal vein thrombosis is an indication for the renal biopsy. A mGn can only be excluded by applying modern morphological methods, i.e. semithin section technique, immunohistology and/or electron microscopy.

Adult↗
PubMed1975

[Kidney biopsy in the differential diagnostic clarification of renal diseases in diabetic patients].

The diagnosis of arteriosclerosis is simple. The chronic pyelonephritis, however, is in most cases not clearly to be diagnosed, but only with a certain probability. To the glomerulosclerosis is applied that conspicuous findings allow of a doubtless diagnosis. But not in the least seldom there exist certain difficulties, above all in the initial stage and in the clear limitation to glomerulonephritis. In the majority of these cases the modern morphologic investigation methods lead to a clarification, but also the exact anamnestic and clinical data may be very useful for a probability diagnosis.

Arteriosclerosis↗