Biomedical subjects

G Delogu

Publications and source records attributed to G Delogu.

61 records · Page 4Linked to original sources

PubMedDate not supplied

[Complex extravascular dislocation of a guidewire during catheterization of the subclavian vein].

A case is presented in which a guidewire, during subclavian catheterization in a 63 years old patient, became knotted outside the vein, behind the clavear head of the sternocleidomastoid muscle. The wire was easily removed by surgical approach and the post operative course was uneventful. The causes of this complication are discussed and a few main points are emphasized when the Seldinger technique is employed for subclavian vein catheterization.

Catheterization, Central Venous↗

PubMedDate not supplied

[Naloxone in ethanol overdose after alcoholization of hepatic metastasis].

The authors report a case of ethanol-induced coma treated successfully with naloxone, in a subject undergoing liver metastasis alcoholization. A dose of ethanol 95 degrees (150 ml) was injected intraoperatively into the hepatic tumor with ultrasound monitoring, in a 55-year old woman which underwent mastectomy two years ago for breast cancer. At the end of operation that went on for 128 minutes, the patient maintained during surgery with standard NLA II anaesthesia did not awake. Toxicologic testing of blood showed an alcohol concentration of 1.9 g/l. Intra-venous naloxone 2 mg was given in boluses of 0.4 mg, through a time of 30 minutes. The patient became progressively responsive with complete recovery 20 minutes later. Since fentanyl doses administered during general anaesthesia were very low, the authors believe that the postoperative coma was due to ethanol overdose. They suggest naloxone as effective treatment to reverse the depressant effects of ethanol following ultrasonically guided alcohol injection therapy.

Adenocarcinoma, Mucinous↗

PubMedDate not supplied

[Thoracoscopic bilateral sympathectomy in Raynaud's syndrome. Anesthesiology problems].

The objective of this paper was to examine the major anaesthetic problems during transthoracic endoscopic sympathectomy without artificial pneumothorax and to present our experience of 16 cases suffering from Raynaud's disease. For the perioperative management we used a double lumen endo-bronchial tube and balanced anaesthesia (intravenous agents plus isoflurane). Arterial pressure, heart rate, ECG, end-tidal carbon dioxide concentration, SatO2, blood gases and peak inspiratory pressures were monitored. The results showed that no significant changes in these parameters occurred during surgery. Since hypoxaemia is the main problem of the thoracoscopic sympathectomy the A.A. emphasize the necessity to ensure a correct ventilation as well as a haemodynamic stability throughout the procedure. The combination of balanced anaesthesia and double lumen endobronchial intubation seems an advisable method when no artificial pnx is instituted. A close monitoring of the circulatory and respiratory systems is imperative.

Adolescent↗

PubMedDate not supplied

[Effects on ventilation secondary to laparoscopic and laparotomic cholecystectomy].

OBJECTIVE: Evaluation of respiratory function after 24 hours from intervention related to two different surgical techniques of cholecistectomy. PATIENTS AND METHODS: Thirty patients submitted to cholecystectomy, nine by laparotomy and twenty-one by video-laparoscopy. The ventilatory parameters considered are as follows: CV, FCV, VEF1, FEF25-75%; and moreover also some variables of acid-base balance: pH, paCO2 e paO. RESULTS: In all cases was evidenced a decrease of respiratory activity. This phenomenon was more evident in the laparotomy group (CV = 37, 35, FCV = 41, 47, VEF1 = 40, FEF25-75% = 36.62% related to preoperative values versus 71.20, 80.88, 79.29, 77.91% in the videolaparoscopic group. No significative differences were registered between the two groups as to postoperative paO2, which was moderately lower in all patients, while no variation was observed for pH and paCO2. CONCLUSIONS: Data collected confirm that after laparoscopic cholecystectomy the ventilatory respiratory capacity is better conserved, that clinically means lower incidence of postoperatory pulmonary complications.

Adult↗

PubMedDate not supplied

["Killing" of pseudomonas aeruginosa isolated from patients with critical post-operative complications. Effect of various antibiotics].

We undertook this study to estimate phagocytic killing by neutrophils (PMNs) of Pseudomonas aeruginosa pre-exposed to sub-inhibitory concentration of Amikacin and Imipenem. In particular, we have isolated bacteria from endotracheal aspirates of post-operative patients mechanically ventilated admitted to an ICU with respiratory failure. PMNs were obtained both from these patients (Group A, n. 6) as well as from subjects submitted to surgery with uncomplicated post-operative period (Group B, n. 8). From specimens tested, 6 strains of Pseudomonas aeruginosa were isolated. Results showed that the rate of killing of bacteria treated with Amikacin was no different from that of untreated bacteria, whichever the source of PMNs, either from Group A or Group B patients. On the other hand, the microbicidal effect on P. aeruginosa exposed to Imipenem was significantly enhanced when PMNs were obtained from Group B patients. In the mixture bacteria, Imipenem and PMNs obtained from Group A the rate of killing was low, similar to the controls without antibiotics. Such a finding suggests a possible impairment of PMNs due to the critical disease and in some way responsible for the host adverse interaction between granulocytes, antibiotics and pathogens. The underlying mechanisms remain to be clarified and further studies are required to understand the possible clinical implications.

Aged↗

PubMedDate not supplied

The treatment of cranio-facial pain by electroacupuncture and laser irradiation.

Craniofacial neuralgias represent an interesting medical challenge, especially regarding the complex therapeutical aspects. Our study was performed treating more than 700 patients, applying steel inox needles variable in diameters and length for about 20 minutes, with a total application number ranging between 10 and 20. Results have been defined referring to a 4-grades response scale: excellent, good, fairly good and insufficient. It is important to emphasise that the best results have been achieved with patients who chose the acupuncture as the first therapeutic approach, while patients who underwent other previous medical and/or surgical treatment have had a worse response. The authors assert that acupuncture and infrared laser reflex therapy represent a harmless and effective treatment of such a diffuse and invalidating disease.

Acupuncture Points↗

PubMedDate not supplied

[Use of the eutectic ointment EMLA (Eutectic Mixture of Local Anesthetics) in the surgical treatment of inguinal hernia under local anesthesia].

The use of EMLA eutectic cream is very effective and well tolerated in superficial anaesthesia. It is particularly indicated in surgical treatment of inguinal hernia by local anaesthesia, to achieve the analgesia of superficial layers. This allows to reduce the total dose of anaesthetics administrated by infiltration, reducing the risk of overdose, eliminating the pain due to injection, and is very agreeable for the patients.

Adult↗