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Biomedical subjects

G De Virgiliis

Publications and source records attributed to G De Virgiliis.

At least 19 recordsLinked to original sources

Junctional pattern in the squamous metaplasia of the female trigone. A freeze-fracture study.

The junctional pattern of squamous metaplasia in the female trigone was studied by the freeze-fracture technique. Desmosomes were observed in all epithelial layers and varied in complexity from the basal to the superficial layers. Gap junctions were observed in the lower and upper epithelial layers. Tight junctions were detected occasionally in the superficial layer only, which appeared as maculae and did not form zonulae occludens. These data support previous suggestions that the squamous metaplastic epithelium is not waterproof and may interfere with the contraction-expansion mechanism of the bladder.

Adult↗

The morphology of early trophoblast after dioxin poisoning in the Seveso area.

The placental morphology in 22 cases of induced abortion performed one to three months after the Seveso disaster is described. In 15 cases no gross histological or ultrastructural alterations were observed. In seven cases there were many prominent microprecipitates beneath the trophoblastic basement membrane at various distances from the fetal capillaries. Intermediate patterns between simple dense bodies, already well known, and complex pluri-stratified giant structures not previously reported have been described. Combined ultrastructural and x-ray investigations (EDAX analysis) have recorded calcium- and iron-related emissions from these structures. The significance of these findings and their possible relationship to dioxin poisoning has been discussed.

Abortion, Therapeutic↗