Methotrexate. Mechanism of action on DNA synthesis in psoriasis.
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Autoradiography↗
Biomedical subjects
G D Weinstein
Publications and source records attributed to G D Weinstein.
Androgenic regulation of nucleic acid and protein synthesis in the hamster flank organ and other tissues.
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Amino Acids↗
Syndrome of unilateral ectromelia, psoriasis and central nervous system anomalies.
A patient presenting with unilateral ectromelia, psoriasiform dermatosis and central nervous system abnormalities has been studied. Four similar cases have been reported in the literature. Autoradiographic studies of the turnover rate of epidermal cells in the patient's affected skin revealed markedly increased proliferative activity which is consistent with the diagnosis of psoriasis. Also consistent with this diagnosis was the response to a therapeutic trial of systemic methotrexate.
Abnormalities, Multiple↗
Methotrexate for psoriasis. A new therapeutic schedule.
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Administration, Oral↗
Autoradiographic analysis of cell proliferation kinetics in human genital tissues. I. Normal cervix and vagina.
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Autoradiography↗
Diagnosis of Lesch-Nyhan syndrome by direct study of skin specimens.
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Adenine↗
Localized epidermolytic hyperkeratosis. A form of keratoderma of the palms and soles.
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Adult↗
Fluorouracil: mechanism of action in human skin and actinic keratoses. I. Effect on DNA synthesis in vivo.
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Chemical Phenomena↗
Location of proliferating cells in human epidermis.
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Autoradiography↗
Cell proliferation in human basal cell carcinoma.
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Adult↗
Evaluation of possible chronic hepatotoxicity from methotrexate for psoriasis.
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Adult↗
Topical administration of Vitamin A acid for ichthyosiform dermatoses and psoriasis.
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Acids↗
Metabolism of progesterone-4-14C in vitro in human skin and vaginal mucosa.
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Abdomen↗
Cell proliferation kinetics in benign and malignant skin diseases in humans.
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Autoradiography↗
Ichthyosiform dermatoses. 3. Studies of transepidermal water loss.
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Adolescent↗
Kinetics of human epidermal cell proliferation: diurnal variation.
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Adult↗
In vitro interconversion of estrone and 17-beta-estradiol in human skin and vaginal mucosa.
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Carbon Isotopes↗
Abnormal cell proliferation in psoriasis.
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Adult↗