[Incidents and accidents in fluorescence angiography].
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Biomedical subjects
Publications and source records attributed to G Coscas.
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Two cases of choriocapillaris occlusion in Moschowitz's disease were examined. The first case was seen at the acute stage with severe findings including retinal detachment, yellowish spots, dye leakage in the subretinal space. Pathology examination revealed multiples choriocapillaris occlusions and foci of pigmentary epithelial necrosis. The second case was seen at the sequelar stage, with numerous Elschnig's spots well documented by angiography. Relationship between angiographic and pathologic findings are discussed, and emphasize the various kinds of blood retinal barrier rupture at the level of pigmentary epithelium.
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In five young adults, mild vitreous hemorrhage occurred from the area of retinal loops near or on the optic nerve. In all cases, the hemorrhage cleared without further complications. This vascular congenital malformation may be associated with secondary complications more frequently than has previously been reported.
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The evolution of a case of acute occlusion of the choriocapillaris, with retinal detachment, during a toxemia of pregnancy is reported. The evolution of the angiographic findings are studied. At the acute stage, some spots of leakage appeared in the area of choroïdal filling defect. The healing results in Elschnig's spots, which take up an area much smaller than the initial non perfusion. The various stages of ischaemic involvement of retinal pigmentary epithelium and their angiographic aspects are discussed.
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Ocular electrophysiology investigations are essential for detecting retinal complications of prolonged treatment with synthetic antimalarial agents. The techniques employed and the principal lesions discovered by the examination are described. The analysis of lesions found in 29 out of 120 cases examined showed that only simple close surveillance was necessary in 17 cases, a reduction in daily dosage in 11 cases, and interruption of treatment in one case only. The modalities of ocular electrophysiology surveillance during prolonged treatment with antimalarial agents are outlined.
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