DHAP treatment: results of 18 patients with refractory or recurrent non Hodgkin's lymphoma.
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Adolescent↗
Biomedical subjects
G Cimino
Publications and source records attributed to G Cimino.
Third-line chemotherapy with CAVP (CCNU, melphalan, etoposide and prednisone) in refractory Hodgkin's disease.
Thirty-one patients affected by recurrent Hodgkin's disease have been treated with an oral combination chemotherapy including lomustine (CCNU 90 mg/sqm, on day 1), melphalan (Alkeran, 7.5 mg/sqm on days 1-5), etoposide (VP-16, 100 mg/sqm on days 6-10) and prednisone (40 mg/sqm on days 1-10). MOPP and ABVD regimens administered sequentially or in alternating fashion had been employed as first choice treatment. The majority of patients had extranodal (80%) and a progressive disease resistant to previous chemotherapy (80%). Complete and partial remission were induced in 8 (26%) and 5 patients (16%), respectively, with an overall response rate of 42%. Median duration of complete remission was 10 months. Patients who did not respond to previous chemotherapies had a significantly lower complete response rate (16%). Myelosuppression was the most frequent complication, with one patient dying of a thrombocytopenic hemorrhage. The oral administration of drugs allowed good patients', compliance with treatment. CAVP is an effective regimen in the management of patients with refractory Hodgkin's disease and the results obtained are comparable with other third-line chemotherapies.
Adolescent↗
Prognosis and management of patients affected by multi pre-treated Hodgkin's disease.
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Antineoplastic Combined Chemotherapy Protocols↗
Gastric antral vascular ectasia (the watermelon stomach): a brief case report.
Herein, the endoscopic and histological features of a case of gastric antral vascular ectasia (watermelon stomach) occurring in a 76-year-old woman are described. The condition, first recognized by Jabbari et al in 1984, is a rare but important cause of severe gastrointestinal blood loss and chronic iron deficiency anemia. Differential diagnosis from portal hypertensive gastropathy, treatment and outcome of the watermelon stomach are discussed.
Aged↗