After a short introduction regarding the physiopathology of secondary spleen cysts, the authors describe a personally observed case of voluminous hemorrhagic pseudocyst. They underline the rarity of the orientation towards radical surgery, having in mind the post-splenectomy risks determined by deficiency of important spleen functions. The authors, with respect to this, underline the importance of reimplanting splenic tissue fragment into omentum, promoting to use, in selected cases, this treatment that needs, however, further clinical findings.

Adolescent↗

PubMedDate not supplied

Rapid and transient lymphocytopenia after i.v. administration of high doses of human recombinant erythropoietin.

The effect of administration of human recombinant erythropoietin on leukocytic cells has been evaluated. In humans the administration of 20,000 U i.v. of rHuEPO caused a rapid and transitory leukopenia that seemed to be caused by a preferential reduction of lymphocytes (2715 +/- 513 mm3 t 0; 1898 +/- 506 t 60', p < 0.002). Pretreatment with imidazole-2-hydroxybenzoate, a drug capable of inhibiting the synthesis of prostaglandins, caused a less marked and later reduction of lymphocytes (2242 +/- 477 t 0; 1560 +/- 318 t 180 minutes, p < 0.001). A less marked and later lymphocytopenia was also shown in subjects affected by chronic renal insufficiency (2907 +/- 726 t 0; 1944 +/- 512 t 180 minutes, p < 0.005).

Erythropoietin↗

PubMedDate not supplied

A case of recurrent dermatofibrosarcoma protuberans.

The authors report a case of DFSP with one true and one successive false recurrence. The characteristics of this tumour are reviewed together with the current trends of therapy.

Adult↗