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Biomedical subjects

G Caselli

Publications and source records attributed to G Caselli.

At least 73 records · Page 4Linked to original sources
PubMed1980

Wenckebach second-degree A-V block in top-ranking athletes: an old problem revisited.

The occurrence of Wenckebach second-degree (Mobitz I) A-V block in apparently normal persons still provides a puzzle for the cardiologist, as the benign nature of this event has been recently questioned. This problem becomes more intriguing when Wenckebach A-V block is encountered in asymptomatic top-ranking athletes, because of medico-legal implications. We report 10 cases of highly-trained athletes, including three with mitral valve prolapse (MVP) features, with a spontaneous or induced Wenckebach second-degree A-V block. Previous ECGs of six subjects, dating from a maximum of 6 years to a minimum of 18 months, were available. Deterioration of A-V conduction has never been documented and all six cases have remained asymptomatic for the whole follow-up period. Athletes have been submitted to a protocol study consisting of ECG recording at rest, during, and after vagal and sympathetic reflex maneuvers, drug administration (isoproterenol and atropine), submaximal and maximal exercise. Nine subjects have been considered to have "normal" responses of the A-V node to provocative tests, since conduction disturbances were improved or normalized by reflex sympathetic stimulations and were completely normalized by autonomic drug administration and exercise. One athlete showed "abnormal" responses to tests. In order to give a conclusive prognostic and medico-legal assessment, we advised him to submit to an invasive electrophysiological investigation. Wenckebach second-degree A-V block in athletes may be a more common finding than so far described, especially when a systematic search is made. In our opinion, this event can still be considered a vagally-induced benign feature of athlete's heart, provided that an immediate improvement of A-V conduction is obtained in response to reflex sympathetic maneuvers, and that a complete normalization after sympathomimetic and vagolytic drug administration and physical exercise is observed. The clinical histories of our athletes and the observed complete disappearance of conduction disturbances after detraining, strongly support this opinion. Wenckebach second-degree A-V block in asymptomatic athletes with MVP features probably does not affect the prognosis if similar favorable responses to the aforesaid tests are observed.

Adolescent↗
PubMedDate not supplied

[Multivariate methods in the analysis of the relationships between mortality and socioeconomic, environmental, and individual behavioral variables].

This study is concerned with the relationships between geographic factors and mortality from external causes, such as environmental pollution, nutrition, and socioeconomic factors. It is based on Italian data on the mortality of adult males aged 25 years and over. The results show that "degenerative diseases, from middle age onwards, are typical sicknesses of the more highly industrialised and richer areas, [particularly] where economic development has not been accompanied by action to preserve the environment from pollution. Diseases which medical and therapeutic progress have rendered almost harmless continue to strike the populations of the poorer areas, where adequate hygienic and sanitary structures are lacking." (summary in ENG, ITA)

Adult↗
PubMedDate not supplied

Mortality in Italy: contours of a century of evolution.

The authors construct contour maps of Italian male and female mortality rates for ages 0-79 for the years 1870-1979 using life table data from published sources. The maps "display persistent global and prominent local patterns of mortality, simultaneously over age, by period, and for cohorts." Previously documented aspects of the evolution of Italian mortality are highlighted graphically, and new areas for study are indicated. (summary in FRE, ITA)

Cohort Studies↗
PubMedDate not supplied

[An adjustment to the age structure of the Italian population in the 1971 census].

"Having verified, in the 1971 [Italian] census, the presence of certain anomalous data for cohorts born in 1900, 1911, 1920, 1924, 1930, 1936, 1940, 1948, 1950 and 1960, we assessed the size of the error and estimated the new population total which emerged both by age and year of birth. The method used [is similar] to more classical methods to correct biases in age structure in previous censuses and in those countries where the data available are somewhat lacking. The adjusted values, referring to Italy as a whole, are contained in the text...." (SUMMARY IN ENG AND FRE)

Age Distribution↗
PubMedDate not supplied

Estimation of the number of persons at advanced ages from the number of deaths at each age in the given year and adjacent years.

"In this article the rate of increase of the population at each age is estimated from the rate of increase in the number of deaths, and in this way a close approximation of the number of older persons at each age is derived from the accurately recorded number of deaths in three consecutive years centered on the year in question. The method is illustrated by applying it to Sweden, England and Wales, and Italy." (SUMMARY IN FRE AND ITA)

Age Distribution↗
PubMedDate not supplied

A new insight into morbidity and mortality transition in Italy.

"Average life expectancy in Italy more than doubled over the last 100 years, rising from 36 years in 1887 for both sexes to 72 and 79 years for men and women, respectively, by 1986.... The aim of the present study is to interpret this trend in the light of the mortality dynamic by age and...the health transition which began in Italy at the close of the last century. By reconstructing the annual data necessary for this purpose it will be possible to pin-point how and when changes took place in the cause-specific mortality structure and what impact these changes had in either accelerating or curbing improvements in life expectancy." (SUMMARY IN FRE AND ITA)

Cause of Death↗
PubMedDate not supplied

The geography of adult mortality: results from the fuzzy clumping method.

"This study analyses provincial differences in adult mortality (separately for men and women, aged 30-64 years) in Italy between 1984 [and] 1987.... By applying the fuzzy clumping method to mortality rates by cause...groups of provinces can be identified where mortality profiles (irrespective of the intensity) are not only similar for all or only for some of the mortality causes considered, but also specify the grade of similarity common to the provinces in the same group. This method, whereby any single province can belong to several groups, provides an image of the geography of mortality where homogeneous groups are not separated by fixed boundaries but may actually have provinces in common." (SUMMARY IN ITA)

Cause of Death↗